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Tsutomu Takeuchi

Tsutomu Takeuchi

D-Index & Metrics

Medicine

D-Index
105
Citations
54436
World Ranking
6680
National Ranking
155

Overview

Tsutomu Takeuchi is affiliated with Keio University in Japan and has a research focus primarily within the field of Medicine, with notable contributions to Rheumatology. Their scholarly work is concentrated on autoimmune and inflammatory disorders, particularly rheumatoid arthritis and systemic lupus erythematosus.

The scientist's publication record includes research addressing fundamental and clinical aspects of autoimmune diseases, with a strong emphasis on treatment strategies and therapeutic advancements.

Recent prominent papers include:

  • EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update (2020, Annals of the Rheumatic Diseases)
  • EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update (2022, Annals of the Rheumatic Diseases)
  • Translating IL-6 biology into effective treatments (2020, Nature Reviews Rheumatology)
  • Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a consensus statement (2020, Annals of the Rheumatic Diseases)
  • Efficacy and Safety of Upadacitinib Monotherapy in Methotrexate-Naive Patients With Moderately-to-Severely Active Rheumatoid Arthritis (SELECT-EARLY): A Multicenter, Multi-Country, Randomized, Double-Blind, Active Comparator-Controlled Trial (2020, Arthritis & Rheumatology)

Frequent collaborators in research include:

  • Yoshiya Tanaka
  • Yuko Kaneko
  • Katsuya Suzuki
  • Jun Kikuchi
  • Masayoshi Harigai

Tsutomu Takeuchi's research is often disseminated through several key academic journals, notably:

  • Annals of the Rheumatic Diseases
  • Modern Rheumatology
  • Lara D. Veeken
  • Arthritis Research & Therapy
  • Arthritis & Rheumatology

Their work spans several subfields of study including:

  • Rheumatology
  • Genetics
  • Immunology
  • Hematology
  • Pathology and Forensic Medicine

Main topics covered by their research encompass:

  • Rheumatoid Arthritis Research and Therapies
  • Systemic Lupus Erythematosus Research
  • Chronic Lymphocytic Leukemia Research
  • Autoimmune and Inflammatory Disorders Research
  • Lymphoma Diagnosis and Treatment
  • Monoclonal and Polyclonal Antibodies Research
  • Vasculitis and related conditions

Best Publications

  • EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

    Josef S Smolen;Robert Landewé;Ferdinand C Breedveld;Maya Buch;Maya Buch

  • Innate production of T H 2 cytokines by adipose tissue-associated c-Kit + Sca-1 + lymphoid cells

    Kazuyo Moro;Taketo Yamada;Masanobu Tanabe;Tsutomu Takeuchi

  • Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force

    Josef S Smolen;Ferdinand C Breedveld;Gerd R Burmester;Vivian Bykerk

  • Treatment of rheumatoid arthritis with humanized anti–interleukin-6 receptor antibody: A multicenter, double-blind, placebo-controlled trial

    Norihiro Nishimoto;Kazuyuki Yoshizaki;Nobuyuki Miyasaka;Kazuhiko Yamamoto

  • Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

    Norihiro Nishimoto;Jun Hashimoto;Nobuyuki Miyasaka;Kazuhiko Yamamoto

  • PI3K-mediated negative feedback regulation of IL-12 production in DCs

    Taro Fukao;Masanobu Tanabe;Yasuo Terauchi;Takayuki Ota

  • Translating IL-6 biology into effective treatments.

    Ernest Hs Choy;Fabrizio De Benedetti;Tsutomu Takeuchi;Misato Hashizume

  • Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy

    Norihiro Nishimoto;Nobuyuki Miyasaka;Kazuhiko Yamamoto;Shinichi Kawai

  • Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis

    Tsutomu Takeuchi;Y. Tatsuki;Y. Nogami;N. Ishiguro

  • An Evolutionarily Conserved Mechanism for MicroRNA-223 Expression Revealed by MicroRNA Gene Profiling

    Taro Fukao;Yoko Fukuda;Kotaro Kiga;Jafar Sharif

  • Lymphoproliferative disorders in rheumatoid arthritis: clinicopathological analysis of 76 cases in relation to methotrexate medication.

    Yoshihiko Hoshida;Jing Xian Xu;Shigeki Fujita;Itsuko Nakamichi

  • Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study

    Norihiro Nishimoto;Nobuyuki Miyasaka;Kazuhiko Yamamoto;Shinichi Kawai

  • Baricitinib, Methotrexate, or Combination in Patients With Rheumatoid Arthritis and No or Limited Prior Disease-Modifying Antirheumatic Drug Treatment

    Roy Fleischmann;Michael Schiff;Désirée van der Heijde;Cesar Ramos-Remus

  • Immunogenicity of Biologics in Chronic Inflammatory Diseases: A Systematic Review

    Vibeke Strand;Alejandro Balsa;Jamal Al-Saleh;Leonor Barile-Fabris

  • Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells

    Masashi Ohtani;Shigenori Nagai;Shuhei Kondo;Shinta Mizuno

  • Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still's disease.

    Masanori Kawashima;Masahiro Yamamura;Madoka Taniai;Hiroshi Yamauchi

  • Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study

    Y Tanaka;T Takeuchi;T Mimori;K Saito

  • Effect of Filgotinib vs Placebo on Clinical Response in Patients with Moderate to Severe Rheumatoid Arthritis Refractory to Disease-Modifying Antirheumatic Drug Therapy: The FINCH 2 Randomized Clinical Trial

    Mark C. Genovese;Kenneth Kalunian;Jacques Eric Gottenberg;Neelufar Mozaffarian

  • Serum indicators for the diagnosis of pneumocystis pneumonia

    Sadatomo Tasaka;Naoki Hasegawa;Seiki Kobayashi;Wakako Yamada

  • Combination therapy with corticosteroids, cyclosporin A, and intravenous pulse cyclophosphamide for acute/subacute interstitial pneumonia in patients with dermatomyositis.

    Hideto Kameda;Hayato Nagasawa;Hiroe Ogawa;Naoya Sekiguchi

Frequent Co-Authors

Yoshiya Tanaka
Yoshiya Tanaka University of Occupational and Environmental Health Japan
Hisashi Yamanaka
Hisashi Yamanaka International University of Health and Welfare
Nobuyuki Miyasaka
Nobuyuki Miyasaka Tokyo Medical and Dental University
Naoki Ishiguro
Naoki Ishiguro Nagoya University
Kazuo Tsubota
Kazuo Tsubota Keio University
Takao Koike
Takao Koike Hokkaido University
Masataka Kuwana
Masataka Kuwana Nippon Medical School
Tatsuya Atsumi
Tatsuya Atsumi Hokkaido University
Josef S. Smolen
Josef S. Smolen Medical University of Vienna

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