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Overview

Hisashi Yamanaka is affiliated with the International University of Health and Welfare in Japan. Their research primarily focuses on medicine, with a strong emphasis on rheumatology. The subfields they have contributed to include rheumatology, genetics, pathology and forensic medicine, hematology, and nephrology.

Their recent publications address various aspects of rheumatology and related conditions. Notable papers include:

  • Drug treatment algorithm and recommendations from the 2020 update of the Japan College of Rheumatology clinical practice guidelines for the management of rheumatoid arthritis-secondary publication (2022, Modern Rheumatology)
  • Evaluation of VTE, MACE, and Serious Infections Among Patients with RA Treated with Baricitinib Compared to TNFi: A Multi-Database Study of Patients in Routine Care Using Disease Registries and Claims Databases (2022, Rheumatology and Therapy)
  • Real-world treatment of gout and asymptomatic hyperuricemia: A cross-sectional study of Japanese health insurance claims data (2020, Modern Rheumatology)
  • Urate-lowering therapy for CKD patients with asymptomatic hyperuricemia without proteinuria elucidated by attribute-based research in the FEATHER Study (2022, Scientific Reports)
  • Serum uric acid control for prevention of gout flare in patients with asymptomatic hyperuricaemia: a retrospective cohort study of health insurance claims and medical check-up data in Japan (2021, Annals of the Rheumatic Diseases)

Yamanaka's work covers a range of main topics including rheumatoid arthritis research and therapies, chronic lymphocytic leukemia research, lymphoma diagnosis and treatment, systemic lupus erythematosus research, autoimmune and inflammatory disorders research, gout, hyperuricemia and uric acid, as well as monoclonal and polyclonal antibodies research.

Frequent coauthors in their research include:

  • Masayoshi Harigai
  • Eisuke Inoue
  • Eiichi Tanaka
  • Katsunori Ikari
  • Naohiro Sugitani

Their studies have been published primarily in several key venues specialized in rheumatology and related medical fields. These publication venues include:

  • Modern Rheumatology
  • Annals of the Rheumatic Diseases
  • Rheumatology and Therapy
  • Clinical Rheumatology
  • BMC Pediatrics

Best Publications

  • Genetics of rheumatoid arthritis contributes to biology and drug discovery

    Yukinori Okada;Yukinori Okada;Di Wu;Di Wu;Di Wu;Gosia Trynka;Gosia Trynka;Towfique Raj;Towfique Raj

  • A retrospective study of the relationship between serum urate level and recurrent attacks of gouty arthritis: Evidence for reduction of recurrent gouty arthritis with antihyperuricemic therapy

    Akira Shoji;Hisashi Yamanaka;Naoyuki Kamatani

  • Comparison of Disease Activity Score (DAS)28- erythrocyte sedimentation rate and DAS28- C-reactive protein threshold values

    Eisuke Inoue;Hisashi Yamanaka;Masako Hara;Taisuke Tomatsu

  • Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis

    Tsutomu Takeuchi;Y. Tatsuki;Y. Nogami;N. Ishiguro

  • Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

    Yukinori Okada;Chikashi Terao;Katsunori Ikari;Yuta Kochi

  • Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses.

    Wako Urano;Atsuo Taniguchi;Hisashi Yamanaka;Eiichi Tanaka

  • Herpes Zoster and Tofacitinib Therapy in Patients With Rheumatoid Arthritis

    Kevin L. Winthrop;Hisashi Yamanaka;Hernan Valdez;Eric Mortensen

  • Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis

    Takahisa Gono;Shinji Sato;Yasushi Kawaguchi;Masataka Kuwana

  • Clinical manifestation and prognostic factor in anti-melanoma differentiation-associated gene 5 antibody-associated interstitial lung disease as a complication of dermatomyositis

    Takahisa Gono;Yasushi Kawaguchi;Takashi Satoh;Masataka Kuwana

  • A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.

    Yuta Kochi;Yukinori Okada;Akari Suzuki;Katsunori Ikari

  • Japanese Guideline for the Management of Hyperuricemia and Gout: Second Edition

    Hisashi Yamanaka

  • DOES HYPERURICEMIA AEFFECT MORTALITY? A Prospective Cohort Study of Japanese Male Workers

    Masako Tomita;Shouichi Mizuno;Hisashi Yamanaka;Yutaka Hosoda

  • Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA Study

    Tuulikki Sokka;Hannu Kautiainen;Theodore Pincus;Suzanne M.M. Verstappen

  • Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial

    Kenjiro Kimura;Tatsuo Hosoya;Shunya Uchida;Masaaki Inaba

  • Serum matrix metalloproteinase 3 as a predictor of the degree of joint destruction during the six months after measurement, in patients with early rheumatoid arthritis.

    Hisashi Yamanaka;Yuko Matsuda;Michi Tanaka;Wako Sendo

  • The inflammatory process in the mechanism of decreased serum uric acid concentrations during acute gouty arthritis

    Wako Urano;Hisashi Yamanaka;Hiroshi Tsutani;Hiroshi Nakajima

  • Validation of a Japanese version of the Stanford Health Assessment Questionnaire in 3,763 patients with rheumatoid arthritis

    Yuko Matsuda;Gurkirpal Singh;Hisashi Yamanaka;Eiichi Tanaka

  • Safety and effectiveness of adalimumab in Japanese rheumatoid arthritis patients: postmarketing surveillance report of the first 3,000 patients

    Takao Koike;Masayoshi Harigai;Naoki Ishiguro;Shigeko Inokuma

  • Cytokine profiles in polymyositis and dermatomyositis complicated by rapidly progressive or chronic interstitial lung disease

    Takahisa Gono;Hirotaka Kaneko;Yasushi Kawaguchi;Masanori Hanaoka

  • Postmarketing surveillance of tocilizumab for rheumatoid arthritis in Japan: interim analysis of 3881 patients

    Takao Koike;Masayoshi Harigai;Shigeko Inokuma;Naoki Ishiguro

Frequent Co-Authors

Naoyuki Kamatani
Naoyuki Kamatani StaGen (Japan)
Yoshiya Tanaka
Yoshiya Tanaka University of Occupational and Environmental Health Japan
Tsutomu Takeuchi
Tsutomu Takeuchi Keio University
Masako Hara
Masako Hara National Defense Medical College
Yasushi Kawaguchi
Yasushi Kawaguchi University of Tokyo
Takao Koike
Takao Koike Hokkaido University
Naoki Ishiguro
Naoki Ishiguro Nagoya University
Tsuneyo Mimori
Tsuneyo Mimori Kyoto University
Nobuyuki Miyasaka
Nobuyuki Miyasaka Tokyo Medical and Dental University

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