His scientific interests lie mostly in Immunology, Internal medicine, Beta 2-Glycoprotein I, Antibody and Antiphospholipid syndrome. Immunology and Single-nucleotide polymorphism are frequently intertwined in his study. His Internal medicine research is multidisciplinary, relying on both Gastroenterology and Endocrinology.
The study incorporates disciplines such as Molecular biology, Plasma protein binding, Biochemistry and Immunoglobulin G in addition to Beta 2-Glycoprotein I. His Antibody research integrates issues from Beta and Antigen. His biological study deals with issues like Lupus anticoagulant, which deal with fields such as Catastrophic antiphospholipid syndrome, Anti-cardiolipin antibodies, Risk factor and Odds ratio.
His primary areas of study are Internal medicine, Immunology, Antibody, Rheumatoid arthritis and Antiphospholipid syndrome. His Internal medicine research incorporates themes from Gastroenterology, Endocrinology and Surgery. His Immunology study frequently draws connections between adjacent fields such as Transplantation.
Takao Koike has included themes like Postmarketing surveillance, Adverse effect, Infliximab and Arthritis in his Rheumatoid arthritis study. His Antiphospholipid syndrome research is multidisciplinary, incorporating elements of Lupus anticoagulant and Platelet. The various areas that Takao Koike examines in his Beta 2-Glycoprotein I study include Molecular biology and Biochemistry.
His main research concerns Internal medicine, Rheumatoid arthritis, Surgery, Methotrexate and Gastroenterology. Within one scientific family, Takao Koike focuses on topics pertaining to Placebo under Internal medicine, and may sometimes address concerns connected to Pharmacokinetics and Dosing. Many of his research projects under Rheumatoid arthritis are closely connected to In patient with In patient, tying the diverse disciplines of science together.
His Surgery study incorporates themes from Cerebral infarction, Severity of illness and Bacterial pneumonia. His work in Rheumatology addresses subjects such as Immunology, which are connected to disciplines such as Cancer research. His Lupus anticoagulant study is concerned with the larger field of Antibody.
Takao Koike mainly investigates Internal medicine, Rheumatoid arthritis, Surgery, Gastroenterology and Placebo. Takao Koike performs integrative Internal medicine and In patient research in his work. His studies deal with areas such as Postmarketing surveillance, Clinical trial, Vascularity and Abatacept as well as Rheumatoid arthritis.
The concepts of his Surgery study are interwoven with issues in Severity of illness and Arthritis. His Gastroenterology study combines topics in areas such as Pharmacokinetics and Rheumatoid factor. His work investigates the relationship between Rheumatology and topics such as Immunology that intersect with problems in Cancer research.
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International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).
S. Miyakis;M. D. Lockshin;T. Atsumi;D. W. Branch.
Journal of Thrombosis and Haemostasis (2006)
International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop.
Wendell A. Wilson;Azzudin E. Gharavi;Takao Koike;Michael D. Lockshin.
Arthritis & Rheumatism (1999)
Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface.
Eiji Matsuura;Yoshiko Igarashi;Tatsuji Yasuda;Douglas A. Triplett.
Journal of Experimental Medicine (1994)
Advanced Glycation End Products in Alzheimer's Disease and Other Neurodegenerative Diseases
Nobuyuki Sasaki;Ryo Fukatsu;Kayo Tsuzuki;Yorihide Hayashi.
American Journal of Pathology (1998)
Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis
Tsutomu Takeuchi;Y. Tatsuki;Y. Nogami;N. Ishiguro.
Annals of the Rheumatic Diseases (2008)
A functional variant in FCRL3 , encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities
Yuta Kochi;Ryo Yamada;Akari Suzuki;John B. Harley;John B. Harley;John B. Harley.
Nature Genetics (2005)
Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice.
M A Mieza;T Itoh;J Q Cui;Y Makino.
Journal of Immunology (1996)
Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies
Elena Raschi;Cinzia Testoni;Daniela Bosisio;Maria O. Borghi.
Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant.
Tatsuya Atsumi;Masahiro Ieko;Maria L. Bertolaccini;Kenji Ichikawa.
Arthritis & Rheumatism (2000)
Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation
Sakurako Nakamura;Zenji Makita;Shintaro Ishikawa;Koichi Yasumura.
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