World's Best Scientists 2026 revealed!

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Immunology

D-Index
89
Citations
40529
World Ranking
1098
National Ranking
41

Medicine

D-Index
91
Citations
41517
World Ranking
11569
National Ranking
340

Overview

Takao Koike is affiliated with Hokkaido University in Japan and has contributed extensively to the field of medicine, with a primary focus on rheumatology among other subfields.

Their research encompasses various specific topics, including:

  • Rheumatoid Arthritis Research and Therapies
  • Systemic Lupus Erythematosus Research
  • Mycobacterium Research and Diagnosis
  • Chronic Kidney Disease and Diabetes
  • Blood Pressure and Hypertension Studies
  • Renal Function and Acid-Base Balance
  • Monoclonal and Polyclonal Antibodies Research

Koike has published multiple scientific papers, with recent significant works including:

  • "Convolutional neural network for classification of two-dimensional array images generated from clinical information may support diagnosis of rheumatoid arthritis," 2020, Scientific Reports
  • "Roles of Insulin Receptor Substrates (IRS) in renal function and renal hemodynamics," 2020, PLoS ONE
  • "Factors associated with successful discontinuation of certolizumab pegol in early rheumatoid arthritis," 2020, International Journal of Rheumatic Diseases
  • "Risk factors associated with relapse after methotrexate dose reduction in patients with rheumatoid arthritis receiving golimumab and methotrexate combination therapy," 2023, International Journal of Rheumatic Diseases
  • "Comparison of bioelectrical impedance analysis in healthy pregnant women and patient on hemodialysis," 2020, Therapeutic Apheresis and Dialysis

Their work frequently appears in these publication venues:

  • International Journal of Rheumatic Diseases
  • Scientific Reports
  • PLoS ONE
  • Therapeutic Apheresis and Dialysis
  • Case Reports in Nephrology and Dialysis

Research collaborations have involved several frequent co-authors, including:

  • Kazuhide Tanimura
  • Tatsuya Atsumi
  • Seiji Hashimoto
  • Tomochika Maoka
  • Akemi Kitano

Takao Koike's work intersects with multiple medical subfields, predominantly:

  • Rheumatology
  • Nephrology
  • Hematology
  • Epidemiology
  • Cardiology and Cardiovascular Medicine

Best Publications

  • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).

    S. Miyakis;M. D. Lockshin;T. Atsumi;D. W. Branch

  • International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop.

    Wendell A. Wilson;Azzudin E. Gharavi;Takao Koike;Michael D. Lockshin

  • Anticardiolipin cofactor(s) and differential diagnosis of autoimmune disease.

    Eiji Matsuura;Yoshiko Igarashi;Masao Fujimoto;Kenji Ichikawa

  • Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface.

    Eiji Matsuura;Yoshiko Igarashi;Tatsuji Yasuda;Douglas A. Triplett

  • Advanced Glycation End Products in Alzheimer's Disease and Other Neurodegenerative Diseases

    Nobuyuki Sasaki;Ryo Fukatsu;Kayo Tsuzuki;Yorihide Hayashi

  • A functional variant in FCRL3 , encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

    Yuta Kochi;Ryo Yamada;Akari Suzuki;John B. Harley;John B. Harley;John B. Harley

  • Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis

    Tsutomu Takeuchi;Y. Tatsuki;Y. Nogami;N. Ishiguro

  • Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies

    Elena Raschi;Cinzia Testoni;Daniela Bosisio;Maria O. Borghi

  • Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice.

    M A Mieza;T Itoh;J Q Cui;Y Makino

  • Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases

    S Fukaya;S Yasuda;T Hashimoto;K Oku

  • Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant.

    Tatsuya Atsumi;Masahiro Ieko;Maria L. Bertolaccini;Kenji Ichikawa

  • Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study

    Y Tanaka;T Takeuchi;T Mimori;K Saito

  • Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation

    Sakurako Nakamura;Zenji Makita;Shintaro Ishikawa;Koichi Yasumura

  • Endothelial cells as target for antiphospholipid antibodies : Human polyclonal and monoclonal anti-β2-glycoprotein I antibodies react in vitro with endothelial cells through adherent β2-glycoprotein I and induce endothelial activation

    N. Del Papa;L. Guidali;A. Sala;C. Buccellati

  • Efficacy of the antiphospholipid score for the diagnosis of antiphospholipid syndrome and its predictive value for thrombotic events

    Kotaro Otomo;Tatsuya Atsumi;Olga Amengual;Yuichiro Fujieda

  • Preventive Effect of Monoclonal Anti-L3T4 Antibody on Development of Diabetes in NOD Mice

    Takao Koike;Yohjiro Itoh;Tatsuko Ishii;Isao Ito

  • Suppression of transforming growth factor beta and vascular endothelial growth factor in diabetic nephropathy in rats by a novel advanced glycation end product inhibitor, OPB-9195.

    K. Tsuchida;Z. Makita;S. Yamagishi;T. Atsumi

  • Successful Efavirenz Dose Reduction in HIV Type 1-Infected Individuals with Cytochrome P450 2B6 *6 and *26

    Hiroyuki Gatanaga;Tsunefusa Hayashida;Kiyoto Tsuchiya;Munehiro Yoshino

  • Antibodies to β2-glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus

    Akito Tsutsumi;Eiji Matsuura;Kenji Ichikawa;Atsushi Fujisaku

  • Anti-phospholipid antibodies and biological false positive serological test for syphilis in patients with systemic lupus erythematosus.

    T Koike;M Sueishi;H Funaki;H Tomioka

Frequent Co-Authors

Tatsuya Atsumi
Tatsuya Atsumi Hokkaido University
Yoshiya Tanaka
Yoshiya Tanaka University of Occupational and Environmental Health Japan
Eiji Matsuura
Eiji Matsuura Okayama University
Hisashi Yamanaka
Hisashi Yamanaka International University of Health and Welfare
Tsutomu Takeuchi
Tsutomu Takeuchi Keio University
Nobuyuki Miyasaka
Nobuyuki Miyasaka Tokyo Medical and Dental University
Naoki Ishiguro
Naoki Ishiguro Nagoya University
Munther A. Khamashta
Munther A. Khamashta King's College London
Katsumi Eguchi
Katsumi Eguchi Nagasaki University

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