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Masayoshi Takeuchi

Masayoshi Takeuchi

D-Index & Metrics

Medicine

D-Index
82
Citations
20945
World Ranking
16286
National Ranking
510

Overview

Masayoshi Takeuchi is affiliated with Kanazawa Medical University in Japan and has a substantial research output primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work focuses extensively on Clinical Biochemistry, Endocrinology, Diabetes and Metabolism, Pathology and Forensic Medicine, Physiology, and Neurology.

Their principal research topics include Advanced Glycation End Products (AGEs) research, Alcohol Consumption and Health Effects, Diet, Metabolism, and Disease, Liver Disease Diagnosis and Treatment, Alzheimer's disease research and treatments, Diabetic Foot Ulcer Assessment and Management, and Neurological Disorders and Treatments.

Takeuchi has published multiple papers addressing the biochemical and physiological impacts of toxic advanced glycation end products (TAGE). Recent notable publications include:

  • Toxic AGEs (TAGE) theory: a new concept for preventing the development of diseases related to lifestyle, 2020, Diabetology & Metabolic Syndrome
  • Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage, 2021, Biomolecules
  • Effects of Toxic AGEs (TAGE) on Human Health, 2022, Cells

Frequent coauthors collaborating with Takeuchi include Akiko Sakai, Takanobu Takata, Yoshiki Koriyama, Jun-ichi Takino, and Ayako Furukawa, indicating established research partnerships within the biochemical and medical research communities.

The most common publication venues for Takeuchi's work are:

  • Nutrients (5 publications)
  • Biological and Pharmaceutical Bulletin (5 publications)
  • Diabetology & Metabolic Syndrome (3 publications)
  • Research Square (3 publications)
  • Biomolecules (2 publications)

Masayoshi Takeuchi's research contributions predominantly explore the molecular mechanisms underlying disease processes related to lifestyle and metabolism, with particular attention to the role of toxic advanced glycation end-products. The work extends into various clinical and biomedical domains such as diabetes, liver disease, and neurological conditions, reflecting an interdisciplinary approach within medical and biochemical sciences.

Best Publications

  • Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury.

    Hideto Yonekura;Yasuhiko Yamamoto;Shigeru Sakurai;Ralica G. Petrova

  • Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice

    Yasuhiko Yamamoto;Ichiro Kato;Toshio Doi;Hideto Yonekura

  • Advanced glycation end product-induced apoptosis and overexpression of vascular endothelial growth factor and monocyte chemoattractant protein-1 in human-cultured mesangial cells.

    Sho-ichi Yamagishi;Yosuke Inagaki;Tamami Okamoto;Shinjiro Amano

  • Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin

    Tamami Okamoto;Sho ichi Yamagishi;Yosuke Inagaki;Shinjiro Amano

  • Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer’s disease

    Nobuyuki Sasaki;Sadamu Toki;Hiroshi Chowei;Toshikazu Saito

  • RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin.

    Khin Mar Myint;Yasuhiko Yamamoto;Toshio Doi;Ichiro Kato

  • Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease.

    Masayoshi Takeuchi;Sho-ichi Yamagishi

  • Pigment Epithelium-derived Factor Inhibits Advanced Glycation End Product-induced Retinal Vascular Hyperpermeability by Blocking Reactive Oxygen Species- mediated Vascular Endothelial Growth Factor Expression *

    Sho Ichi Yamagishi;Kazuo Nakamura;Takanori Matsui;Yosuke Inagaki

  • AGEs activate mesangial TGF-β–Smad signaling via an angiotensin II type I receptor interaction

    K.E.I. Fukami;Seiji Ueda;Sho-Ichi Yamagishi;Seiya Kato

  • Advanced glycation end products-induced apoptosis and overexpression of vascular endothelial growth factor in bovine retinal pericytes.

    Sho-ichi Yamagishi;Shinjiro Amano;Yosuke Inagaki;Tamami Okamoto

  • Immunological Evidence that Non-carboxymethyllysine Advanced Glycation End-products Are Produced from Short Chain Sugars and Dicarbonyl Compounds in vivo

    Masayoshi Takeuchi;Zenji Makita;Zenji Makita;Richard Bucala;Takako Suzuki

  • Neurotoxicity of advanced glycation end-products for cultured cortical neurons.

    Masayoshi Takeuchi;Richard Bucala;Takako Suzuki;Tadatoshi Ohkubo

  • Pigment epithelium-derived factor protects cultured retinal pericytes from advanced glycation end product-induced injury through its antioxidative properties.

    Sho-ichi Yamagishi;Yosuke Inagaki;Shinjiro Amano;Tamami Okamoto

  • TAGE (toxic AGEs) theory in diabetic complications.

    Takashi Sato;Mina Iwaki;Noriko Shimogaito;Xuegang Wu

  • Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice

    Keigyou Yoh;Aki Hirayama;Kazusa Ishizaki;Akiko Yamada

  • Glycation--a sweet tempter for neuronal death.

    Seiji Kikuchi;Kazuyoshi Shinpo;Masayoshi Takeuchi;Shoichi Yamagishi

  • Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis.

    Hideyuki Hyogo;Sho-ichi Yamagishi;Keiko Iwamoto;Koji Arihiro

  • Valiolamine, a new alpha-glucosidase inhibiting aminocyclitol produced by Streptomyces hygroscopicus.

    Yukihiko Kameda;Naoki Asano;Michiyo Yoshikawa;Masayoshi Takeuchi

  • Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH

    Yuki Kimura;Hideyuki Hyogo;Sho-ichi Yamagishi;Masayoshi Takeuchi

  • Advanced glycation end products inhibit de novo protein synthesis and induce TGF-β overexpression in proximal tubular cells

    Sho-Ichi Yamagishi;Yosuke Inagaki;Yosuke Inagaki;Tamami Okamoto;Tamami Okamoto;Shinjiro Amano;Shinjiro Amano

Frequent Co-Authors

Sho-ichi Yamagishi
Sho-ichi Yamagishi Kurume University
Tsutomu Imaizumi
Tsutomu Imaizumi Kurume University
Naoki Asano
Naoki Asano Hokuriku University
Hiroshi Yamamoto
Hiroshi Yamamoto Komatsu University
Yasuhiko Yamamoto
Yasuhiko Yamamoto Kanazawa University
Richard Bucala
Richard Bucala Yale University
Takao Koike
Takao Koike Hokkaido University
Shigeaki Ohno
Shigeaki Ohno Hokkaido University
Shin Takasawa
Shin Takasawa Nara Medical University
Hiroshi Okamoto
Hiroshi Okamoto Kanazawa University

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