What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Inflammation
Shi Fang Yan mostly deals with Glycation, Receptor, Inflammation, Signal transduction and Immunology.
His study in Glycation focuses on RAGE in particular.
His Receptor study combines topics from a wide range of disciplines, such as Downregulation and upregulation, Immune system and Cell biology.
His Inflammation research includes elements of In vitro and Amyloidosis.
His Signal transduction research is multidisciplinary, relying on both Proinflammatory cytokine, Molecular biology and Diabetes mellitus genetics.
Shi Fang Yan has included themes like Serum response factor, Immediate early protein and Protein kinase A in his Proinflammatory cytokine study.
His most cited work include:
- The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses (1000 citations)
- N ε-(Carboxymethyl)Lysine Adducts of Proteins Are Ligands for Receptor for Advanced Glycation End Products That Activate Cell Signaling Pathways and Modulate Gene Expression (774 citations)
- The biology of the receptor for advanced glycation end products and its ligands. (605 citations)
What are the main themes of his work throughout his whole career to date?
Shi Fang Yan focuses on Internal medicine, Endocrinology, RAGE, Receptor and Glycation.
His Endocrinology research includes themes of Protein kinase C, Vascular disease and Ischemia.
His work carried out in the field of RAGE brings together such families of science as Blockade, Cancer research, Pathology and Advanced Glycation Endproducts.
His Receptor research integrates issues from Inflammation, Immunology, Signal transduction and Downregulation and upregulation.
In his research on the topic of Signal transduction, Serum response factor is strongly related with Protein kinase A.
His biological study deals with issues like Proinflammatory cytokine, which deal with fields such as Homeostasis.
He most often published in these fields:
- Internal medicine (44.16%)
- Endocrinology (43.51%)
- RAGE (38.31%)
What were the highlights of his more recent work (between 2009-2021)?
- Internal medicine (44.16%)
- Endocrinology (43.51%)
- RAGE (38.31%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Internal medicine, Endocrinology, RAGE, Signal transduction and Receptor.
His is involved in several facets of Endocrinology study, as is seen by his studies on Glycation and Diabetes mellitus.
His studies in RAGE integrate themes in fields like Immunology, Pathogenesis, Pathology and Sciatic nerve, Peripheral nerve injury.
His Signal transduction study combines topics in areas such as Inflammation and Reperfusion injury.
His Inflammation research focuses on Diabetes mellitus genetics and how it relates to Immunoglobulin superfamily.
His Receptor research is multidisciplinary, incorporating perspectives in Cancer research, Ischemia, Polyol pathway, Aldose reductase and Gene silencing.
Between 2009 and 2021, his most popular works were:
- Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications. (284 citations)
- The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature. (276 citations)
- RAGE-dependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimer’s disease (207 citations)
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