World's Best Scientists 2026 revealed!
Casper G. Schalkwijk

Casper G. Schalkwijk

D-Index & Metrics

Medicine

D-Index
105
Citations
39143
World Ranking
6790
National Ranking
258

Overview

Casper G. Schalkwijk is affiliated with Maastricht University in the Netherlands and has contributed extensively to research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several notable subfields, including Clinical Biochemistry, Cardiology and Cardiovascular Medicine, Endocrinology, Diabetes and Metabolism, Physiology, and Epidemiology.

The main focus of Schalkwijk's research includes Advanced Glycation End Products (AGEs) research, Cardiovascular Health and Disease Prevention, Diet, Metabolism, and Disease, Liver Disease Diagnosis and Treatment, Alcohol Consumption and Health Effects, Diabetes, Cardiovascular Risks, and Lipoproteins, and Nutritional Studies and Diet.

Key recent publications include:

  • Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour, 2021, Nature Human Behaviour
  • Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis, 2020, Circulation Research
  • Quantification of dicarbonyl compounds in commonly consumed foods and drinks; presentation of a food composition database for dicarbonyls, 2020, Food Chemistry
  • Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS, 2022, Science Translational Medicine
  • Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility, 2021, Food Research International

Frequent co-authors in Schalkwijk's research include:

  • Coen D.A. Stehouwer (105 joint publications)
  • Marleen M. J. van Greevenbroek (60 joint publications)
  • Jean L.J.M. Scheijen (52 joint publications)
  • Carla Kallen (46 joint publications)
  • Simone J. P. M. Eussen (39 joint publications)

Schalkwijk's work has appeared regularly in several publication venues, with multiple contributions in:

  • Diabetologia (8 publications)
  • Scientific Reports (7 publications)
  • Journal of Hypertension (7 publications)
  • Nutrients (6 publications)
  • American Journal of Clinical Nutrition (5 publications)

Best Publications

  • Dietary factors and low-grade inflammation in relation to overweight and obesity

    Philip C. Calder;Namanjeet Ahluwalia;Fred Brouns;Timo Buetler

  • Vascular complications in diabetes mellitus: the role of endothelial dysfunction.

    Casper G. Schalkwijk;Casper G. Schalkwijk;Coen D. A. Stehouwer;Coen D. A. Stehouwer

  • Diastolic Stiffness of the Failing Diabetic Heart Importance of Fibrosis, Advanced Glycation End Products, and Myocyte Resting Tension

    Loek van Heerebeek;Nazha Hamdani;M. Louis Handoko;Ines Falcao-Pires

  • Associations of C-Reactive Protein With Measures of Obesity, Insulin Resistance, and Subclinical Atherosclerosis in Healthy, Middle-Aged Women

    A. E. Hak;C. D. A. Stehouwer;M. L. Bots;K. H. Polderman

  • Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: A possible mechanism through which age is a risk factor for osteoarthritis

    Nicole Verzijl;Jeroen DeGroot;Chaya Ben Zaken;Orit Braun-Benjamin

  • Inflammatory Markers, Adiponectin, and Risk of Type 2 Diabetes in the Pima Indian

    Jonathan Krakoff;Tohru Funahashi;Coen D.A. Stehouwer;Casper G. Schalkwijk

  • Disease variants alter transcription factor levels and methylation of their binding sites.

    Marc Jan Bonder;René Luijk;Daria V Zhernakova;Matthijs Moed

  • Methylglyoxal, a highly reactive dicarbonyl compound, in diabetes, its vascular complications and other age-related diseases

    Casper Schalkwijk;Coen D. Stehouwer

  • Identification of context-dependent expression quantitative trait loci in whole blood

    Daria V Zhernakova;Patrick Deelen;Martijn Vermaat;Maarten van Iterson

  • Plasma concentration of C-reactive protein is increased in Type I diabetic patients without clinical macroangiopathy and correlates with markers of endothelial dysfunction: evidence for chronic inflammation

    C. G. Schalkwijk;D. C. W. Poland;W. van Dijk;A. Kok

  • Genetic and environmental influences interact with age and sex in shaping the human methylome

    Jenny van Dongen;Michel G. Nivard;Gonneke Willemsen;Jouke-Jan Hottenga

  • Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes--the EURODIAB Prospective Complications Study

    M. T. Schram;N. Chaturvedi;C. G. Schalkwijk;J. H. Fuller

  • The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases.

    Dionne E.M. Maessen;Coen D.A. Stehouwer;Casper G. Schalkwijk

  • Humoral markers of inflammation and endothelial dysfunction in relation to adiposity and in vivo insulin action in Pima Indians

    Christian Weyer;John S. Yudkin;Coen D.A. Stehouwer;Casper G. Schalkwijk

  • Obesity-associated low-grade inflammation in type 2 diabetes mellitus: causes and consequences

    M. M. J. van Greevenbroek;C. G. Schalkwijk;C. D. A. Stehouwer

  • Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution.

    Maarten van Iterson;Erik W van Zwet;Bastiaan T Heijmans;Peter a.C ’t Hoen

  • Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial.

    J De Jager;A Kooy;Ph Lehert;D Bets

  • Higher Plasma Levels of Advanced Glycation End Products Are Associated With Incident Cardiovascular Disease and All-Cause Mortality in Type 1 Diabetes: A 12-year follow-up study

    Johanna W. Nin;Anders Jorsal;Isabel Ferreira;Casper G. Schalkwijk

  • Fructose-mediated non-enzymatic glycation: sweet coupling or bad modification

    Casper G. Schalkwijk;Coen D. A. Stehouwer;Victor W. M. van Hinsbergh

  • Vascular Risk Factors and Markers of Endothelial Function as Determinants of Inflammatory Markers in Type 1 Diabetes The EURODIAB Prospective Complications Study

    Miranda T. Schram;Nish Chaturvedi;Casper Schalkwijk;Francesco Giorgino

Frequent Co-Authors

Coen D.A. Stehouwer
Coen D.A. Stehouwer Maastricht University
Marleen M. J. van Greevenbroek
Marleen M. J. van Greevenbroek Maastricht University
Peter Rossing
Peter Rossing University of Copenhagen
Nicolaas C. Schaper
Nicolaas C. Schaper Maastricht University
Edith J. M. Feskens
Edith J. M. Feskens Wageningen University & Research
Giel Nijpels
Giel Nijpels VU University Medical Center
Nish Chaturvedi
Nish Chaturvedi University College London
Victor W.M. van Hinsbergh
Victor W.M. van Hinsbergh University of Amsterdam
Jacqueline M. Dekker
Jacqueline M. Dekker VU University Medical Center
Lise Tarnow
Lise Tarnow Steno Diabetes Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a career in medicine doesn’t always mean attending medical school for an MD. There are several online degrees and certifications that open doors to rewarding roles in healthcare.

If you’re interested in the business and technology side of healthcare, him programs train you to manage patient data and ensure data privacy. For those looking to get started quickly in the healthcare sector, medical coding certification cost is relatively low, making this an accessible entry point with strong job demand.

Nursing remains a versatile and impactful career path. Many students now consider earning their credentials through nurse practitioner programs or through flexible online nursing courses. These pathways let you study at your own pace while preparing for advanced clinical roles or RN licensure.

Each of these online options supports growing healthcare needs across the USA—offering a blend of flexibility, affordability, and strong career prospects.

Best Scientists Citing Casper G. Schalkwijk

Trending Scientists