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Biology and Biochemistry

D-Index
76
Citations
29024
World Ranking
4950
National Ranking
119

Overview

Bastiaan T. Heijmans is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, contributing extensively with 76 and 74 publications respectively. The scientist's work further delves into subfields such as Molecular Biology, Genetics, Pediatrics, Perinatology and Child Health, Immunology, and Epidemiology.

The scientist's research topics prominently include:

  • Epigenetics and DNA Methylation
  • Birth, Development, and Health
  • Assisted Reproductive Technology and Twin Pregnancy
  • Genetic Associations and Epidemiology
  • Prenatal Screening and Diagnostics
  • Atherosclerosis and Cardiovascular Diseases
  • Adipokines, Inflammation, and Metabolic Diseases

Bastiaan T. Heijmans has authored papers in several high-impact journals and venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory) with 14 publications
  • Nature Communications with 5 publications
  • Clinical Epigenetics with 4 publications
  • Molecular Psychiatry with 3 publications
  • Nature Human Behaviour with 2 publications

Recent notable papers include:

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression (2021, Nature Genetics)
  • Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence (2021, Human Molecular Genetics)
  • Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour (2021, Nature Human Behaviour)
  • DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases (2022, Nature Communications)
  • Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression (2022, Genome Biology)

Throughout these works, the scientist has collaborated frequently with several co-authors, including:

  • P. Eline Slagboom
  • Peter A.C. 't Hoen
  • Joyce B. J. van Meurs
  • Dorret I. Boomsma
  • Lude Franke

Best Publications

  • Persistent epigenetic differences associated with prenatal exposure to famine in humans

    Bastiaan T. Heijmans;Elmar W. Tobi;Aryeh D. Stein;Hein Putter

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

    Urmo Võsa;Annique Claringbould;Annique Claringbould;Harm-Jan Westra;Marc Jan Bonder

  • DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

    Elmar W. Tobi;L.H. Lumey;L.H. Lumey;Rudolf P. Talens;Dennis Kremer

  • Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

    Simone Wahl;Alexander Drong;Benjamin Lehne;Marie Loh;Marie Loh;Marie Loh

  • Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    Richard Karlsson Linnér;Richard Karlsson Linnér;Pietro Biroli;Edward Kong;S. Fleur W. Meddens;S. Fleur W. Meddens

  • DNA methylation aging clocks: challenges and recommendations

    Christopher G Bell;Robert Lowe;Peter D Adams;Peter D Adams;Andrea A Baccarelli

  • DNA methylation signatures link prenatal famine exposure to growth and metabolism

    Elmar W. Tobi;Jelle J. Goeman;Ramin Monajemi;Hongcang Gu

  • Periconceptional maternal folic acid use of 400 µg per day is related to increased methylation of the IGF2 gene in the very young child.

    Régine P. Steegers-Theunissen;Sylvia A. Obermann-Borst;Dennis Kremer;Jan Lindemans

  • Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis

    Võsa U;Claringbould A;Westra H;Bonder Mj

  • Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

    J.L. Min;G. Hemani;E. Hannon;K.F. Dekkers

  • Disease variants alter transcription factor levels and methylation of their binding sites.

    Marc Jan Bonder;René Luijk;Daria V Zhernakova;Matthijs Moed

  • Identification of context-dependent expression quantitative trait loci in whole blood

    Daria V Zhernakova;Patrick Deelen;Martijn Vermaat;Maarten van Iterson

  • Genetic and environmental influences interact with age and sex in shaping the human methylome

    Jenny van Dongen;Michel G. Nivard;Gonneke Willemsen;Jouke-Jan Hottenga

  • From promises to practical strategies in epigenetic epidemiology

    Jonathan Mill;Bastiaan T. Heijmans;Bastiaan T. Heijmans;Bastiaan T. Heijmans

  • Epigenetic variation during the adult lifespan: cross‐sectional and longitudinal data on monozygotic twin pairs

    Rudolf P Talens;Kaare Christensen;Kaare Christensen;Hein Putter;Gonneke Willemsen

  • Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology

    Rudolf P. Talens;Dorret I. Boomsma;Elmar W. Tobi;Dennis Kremer

  • Reduced insulin/IGF-1 signalling and human longevity

    Diana Van Heemst;Marian Beekman;Simon P. Mooijaart;Bastiaan T. Heijmans

  • Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

    Joris Deelen;Marian Beekman;Hae-Won Uh;Quinta Helmer

  • Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study.

    Rudi G.J. Westendorp;Diana Van Heemst;Maarten P. Rozing;Marijke Frölich

  • Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution.

    Maarten van Iterson;Erik W van Zwet;Bastiaan T Heijmans;Peter a.C ’t Hoen

Frequent Co-Authors

P. Eline Slagboom
P. Eline Slagboom Leiden University Medical Center
Dorret I. Boomsma
Dorret I. Boomsma Vrije Universiteit Amsterdam
Marian Beekman
Marian Beekman Leiden University Medical Center
Lude Franke
Lude Franke University Medical Center Groningen
Rudi G. J. Westendorp
Rudi G. J. Westendorp University of Copenhagen
Joyce B. J. van Meurs
Joyce B. J. van Meurs Erasmus University Rotterdam
Diana van Heemst
Diana van Heemst Leiden University Medical Center
Peter A. C. 't Hoen
Peter A. C. 't Hoen Radboud University
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Marleen M. J. van Greevenbroek
Marleen M. J. van Greevenbroek Maastricht University

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