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Neuroscience

D-Index
93
Citations
40429
World Ranking
965
National Ranking
517

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2017 - Member of the National Academy of Sciences
  • 2017 - W. Alden Spencer Award, College of Physicians and Surgeons
  • 2015 - Fellow of the American Academy of Arts and Sciences
  • 1995 - Fellow of Alfred P. Sloan Foundation

Overview

David D. Ginty is affiliated with the Howard Hughes Medical Institute in the United States. Their research primarily focuses on neuroscience and medicine, with significant contributions to several subfields including cellular and molecular neuroscience, cognitive neuroscience, physiology, molecular biology, and sensory systems.

Their recent publications feature work on somatosensory neurons, mechanosensory systems, and tactile perception. Notable papers include:

  • The emergence of transcriptional identity in somatosensory neurons, 2020, Nature
  • The mechanosensory neurons of touch and their mechanisms of activation, 2021, Nature Reviews Neuroscience
  • Parallel ascending spinal pathways for affective touch and pain, 2020, Nature
  • Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception, 2020, Science
  • The cellular and molecular basis of somatosensory neuron development, 2021, Neuron

Their work has been published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature, Cell, Neuron, and Science. These journals represent key platforms for dissemination in neuroscience research.

Frequent co-authors in their collaborations include:

  • Celine Santiago
  • Josef Turecek
  • Brendan P. Lehnert
  • Annie Handler
  • Nikhil Sharma

The scientist's main research topics cover diverse areas such as:

  • Neurobiology and insect physiology research
  • Erythrocyte function and pathophysiology
  • Tactile and sensory interactions
  • Neural dynamics and brain function
  • Pain mechanisms and treatments
  • Ion channel regulation and function
  • Plant and biological electrophysiology studies

Awards received include being named a Fellow of the American Association for the Advancement of Science (2018), recipient of the W. Alden Spencer Award from the College of Physicians and Surgeons (2017), Member of the National Academy of Sciences (2017), Fellow of the American Academy of Arts and Sciences (2015), and Fellow of the Alfred P. Sloan Foundation (1995).

Best Publications

  • Function and Regulation of CREB Family Transcription Factors in the Nervous System

    Bonnie E Lonze;David D Ginty

  • The Sensory Neurons of Touch

    Victoria E. Abraira;David D. Ginty

  • Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase

    Jun Xing;David D. Ginty;Michael E. Greenberg

  • Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways

    Hilmar Bading;David D. Ginty;Michael E. Greenberg

  • Neuropilin is a semaphorin III receptor.

    Alex L. Kolodkin;Dorothy V. Levengood;Erica G. Rowe;Yu Tzu Tai

  • Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock

    David D. Ginty;Jon M. Kornhauser;Margaret A. Thompson;Hilmar Bading;Hilmar Bading

  • Mediation by a CREB Family Transcription Factor of NGF-Dependent Survival of Sympathetic Neurons

    Antonella Riccio;Sohyun Ahn;Christopher M. Davenport;Julie A. Blendy

  • Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance.

    Andrea B. Huber;Alex L. Kolodkin;David D. Ginty;Jean François Cloutier

  • Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB

    David D. Ginty;Azad Bonni;Michael E. Greenberg

  • Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras

    Laura B. Rosen;David D. Ginty;Michael J. Weber;Michael E. Greenberg

  • Neuropilin-1 Conveys Semaphorin and VEGF Signaling during Neural and Cardiovascular Development

    Chenghua Gu;E. Rene Rodriguez;Dorothy V. Reimert;Tianzhi Shu

  • The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

    Lishi Li;Michael Rutlin;Victoria E. Abraira;Colleen Cassidy

  • A Dominant-Negative Inhibitor of CREB Reveals that It Is a General Mediator of Stimulus-Dependent Transcription of c-fos

    Sohyun Ahn;Michelle Olive;Seema Aggarwal;Dmitry Krylov

  • Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins.

    Chenghua Gu;Yutaka Yoshida;Jean Livet;Dorothy V. Reimert

  • Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis.

    Benjamin J. Andreone;Brian Wai Chow;Aleksandra Tata;Baptiste Lacoste

  • The gentle touch receptors of mammalian skin

    Amanda Zimmerman;Ling Bai;David D. Ginty

  • An NGF-TrkA-Mediated Retrograde Signal to Transcription Factor CREB in Sympathetic Neurons

    Antonella Riccio;Brian A. Pierchala;Christopher L. Ciarallo;David D. Ginty

  • Neuropilin-2 Is Required In Vivo for Selective Axon Guidance Responses to Secreted Semaphorins

    Roman J. Giger;Jean François Cloutier;Amar Sahay;Rabinder K. Prinjha

  • The emergence of transcriptional identity in somatosensory neurons

    Nikhil Sharma;Nikhil Sharma;Kali Flaherty;Kali Flaherty;Karina Lezgiyeva;Karina Lezgiyeva;Daniel E. Wagner

  • FUNCTIONS AND MECHANISMS OF RETROGRADE NEUROTROPHIN SIGNALLING

    Larry S. Zweifel;Rejji Kuruvilla;David D. Ginty

  • Effects of PS1 Deficiency on Membrane Protein Trafficking in Neurons

    Satoshi Naruse;Gopal Thinakaran;Jin Jun Luo;John W. Kusiak

Frequent Co-Authors

Alex L. Kolodkin
Alex L. Kolodkin Johns Hopkins University School of Medicine
Michael E. Greenberg
Michael E. Greenberg Harvard University
Chenghua Gu
Chenghua Gu Harvard University
Amar Sahay
Amar Sahay Harvard University
Roman J. Giger
Roman J. Giger University of Michigan–Ann Arbor
Richard L. Huganir
Richard L. Huganir Johns Hopkins University School of Medicine
Marc Tessier-Lavigne
Marc Tessier-Lavigne Xaira Therapeutics
Bradford B. Lowell
Bradford B. Lowell Beth Israel Deaconess Medical Center
Ted M. Dawson
Ted M. Dawson Johns Hopkins University School of Medicine

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