His primary scientific interests are in Semaphorin, Immunology, Cell biology, Immune system and SEMA4D. His Semaphorin research integrates issues from Axon guidance and Neuroscience. His Cell biology research incorporates themes from Cellular differentiation, CD40, T cell, Antigen-presenting cell and Dendritic cell.
The concepts of his Immune system study are interwoven with issues in Cytokine, Antigen and Lactic acid. His SEMA4D research is multidisciplinary, relying on both CD72, Cellular immunity, Stereochemistry, Sema domain and Oligodendrocyte. He has included themes like Cytoplasm, Signal transduction, Function and Phosphorylation in his Receptor study.
His scientific interests lie mostly in Immunology, Semaphorin, Immune system, Internal medicine and Cell biology. His Pathogenesis, Rheumatoid arthritis, Inflammation, Antibody and Autoantibody study are his primary interests in Immunology. The various areas that Atsushi Kumanogoh examines in his Semaphorin study include Axon guidance and Neuroscience.
While the research belongs to areas of Immune system, he spends his time largely on the problem of Cancer research, intersecting his research to questions surrounding Cancer immunotherapy. His study in Internal medicine is interdisciplinary in nature, drawing from both Gastroenterology, Endocrinology and Oncology. The Cell biology study combines topics in areas such as Cytotoxic T cell and Biochemistry.
Atsushi Kumanogoh mostly deals with Internal medicine, Cancer research, Immune system, Immunology and Antibody. The study incorporates disciplines such as Gastroenterology and Cardiology in addition to Internal medicine. His Immune system research incorporates elements of Inflammation, Hypoxia, Pulmonary hypertension and Fibrosis.
His studies link Host with Immunology. As part of one scientific family, Atsushi Kumanogoh deals mainly with the area of Antibody, narrowing it down to issues related to the Immunotherapy, and often Cell, Cytotoxic T cell, T cell, Glucose test and Monoclonal. Cell biology is closely connected to Lymphangioleiomyomatosis in his research, which is encompassed under the umbrella topic of Extracellular vesicles.
His primary areas of investigation include Immune system, Immunology, Cancer research, Antibody and Immunotherapy. Atsushi Kumanogoh has researched Immune system in several fields, including Hypoxia, Pulmonary hypertension and Pathogenesis. His Immunology study incorporates themes from Host and SEMA4D.
His research in Cancer research intersects with topics in Cell, CD8, Cancer immunotherapy, Thymic carcinoma and Cytotoxic T cell. His studies deal with areas such as Strictly standardized mean difference, Nasal Lavage Fluid, Thymoma, Therapeutic effect and Subgroup analysis as well as Antibody. His work deals with themes such as Vasculitis, Flow cytometry, Cytokine and Cytotoxicity, which intersect with Immunotherapy.
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Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders.
Kanji Yoshida;Tetsuya Taga;Mikiyoshi Saito;Sachiko Suematsu.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Osteoprotection by semaphorin 3A
Mikihito Hayashi;Tomoki Nakashima;Masahiko Taniguchi;Tatsuhiko Kodama.
Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling.
Atsushi Kumanogoh;Chie Watanabe;Ihnsook Lee;Xiaosong Wang.
Semaphorins and their receptors in immune cell interactions
Kazuhiro Suzuki;Atsushi Kumanogoh;Hitoshi Kikutani.
Nature Immunology (2008)
Dysbiosis contributes to arthritis development via activation of autoreactive T cells in the intestine
Yuichi Maeda;Takashi Kurakawa;Eiji Umemoto;Daisuke Motooka.
Arthritis & Rheumatism (2016)
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2
Atsushi Kumanogoh;Satoko Marukawa;Kazuhiro Suzuki;Noriko Takegahara.
Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2
Toshihiko Toyofuku;Hong Zhang;Atsushi Kumanogoh;Noriko Takegahara.
Genes & Development (2004)
The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion.
Moreau-Fauvarque C;Kumanogoh A;Camand E;Jaillard C.
The Journal of Neuroscience (2003)
The class IV semaphorin CD100 plays nonredundant roles in the immune system : defective B and T cell activation in CD100-deficient mice
Wei Shi;Atsushi Kumanogoh;Chie Watanabe;Junji Uchida.
Semaphorin 7A initiates T-cell-mediated inflammatory responses through α1β1 integrin
Kazuhiro Suzuki;Tatsusada Okuno;Midori Yamamoto;R. Jeroen Pasterkamp.
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