World's Best Scientists 2026 revealed!
Alain Chédotal

Alain Chédotal

D-Index & Metrics

Neuroscience

D-Index
83
Citations
21140
World Ranking
1475
National Ranking
47

Research.com Recognitions

  • 2015 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Alain Chédotal is affiliated with the Institut de la Vision in France and has established a research profile spanning multiple disciplines, with a significant focus in biochemistry, genetics, molecular biology, and neuroscience. Their publication record demonstrates engagement with core areas of medicine as well as specialized subfields of molecular biology, cellular and molecular neuroscience, developmental neuroscience, genetics, and radiology.

Their research topics cover a broad spectrum within neuroscience and developmental biology, including:

  • Axon Guidance and Neuronal Signaling
  • Neurogenesis and neuroplasticity mechanisms
  • Retinal Development and Disorders
  • Single-cell and spatial transcriptomics
  • Developmental Biology and Gene Regulation
  • Congenital heart defects research
  • Renal and related cancers

Chédotal has authored and co-authored numerous publications across high-impact and specialized scientific journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Neuron
  • eLife
  • Nature reviews. Neuroscience

Recent notable papers featuring their research include the following:

  • "Tissue clearing and its applications in neuroscience", 2020, published in Nature reviews. Neuroscience
  • "Single-cell roadmap of human gonadal development", 2022, published in Nature
  • "A roadmap for the Human Developmental Cell Atlas", 2021, published in Nature
  • "A human embryonic limb cell atlas resolved in space and time", 2023, published in Nature
  • "Yolk sac cell atlas reveals multiorgan functions during human early development", 2023, published in Science

The scientist frequently collaborates with several colleagues, including:

  • Yorick Gitton
  • Séverine Mazaud-Guittot
  • Raphaël Blain
  • Juan Antonio Moreno-Bravo
  • Omer Ali Bayraktar

Alain Chédotal has been recognized with memberships in distinguished organizations such as the Academia Europaea since 2015 and the European Molecular Biology Organization (EMBO).

Best Publications

  • Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

    Luca Tamagnone;Stefania Artigiani;Hang Chen;Zhigang He

  • Neuropilin-2, a Novel Member of the Neuropilin Family, Is a High Affinity Receptor for the Semaphorins Sema E and Sema IV but Not Sema III

    Hang Chen;Alain Chédotal;Zhigang He;Corey S Goodman

  • Decoding human fetal liver haematopoiesis

    Dorin-Mirel Popescu;Rachel A. Botting;Emily Stephenson;Kile Green

  • Tissue clearing and its applications in neuroscience

    Hiroki R. Ueda;Ali Ertürk;Kwanghun Chung;Viviana Gradinaru

  • Analysis of the L1-Deficient Mouse Phenotype Reveals Cross-Talk between Sema3A and L1 Signaling Pathways in Axonal Guidance

    Valérie Castellani;Alain Chédotal;Melitta Schachner;Catherine Faivre-Sarrailh

  • Neuropilin-2 Regulates the Development of Select Cranial and Sensory Nerves and Hippocampal Mossy Fiber Projections

    Hang Chen;Anil Bagri;Joel A Zupicich;Yimin Zou

  • Unified nomenclature for the semaphorins/collapsins [1]

    J. A. Bamberg;S. Baumgartner;H. Betz;J. Bolz

  • The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion.

    Moreau-Fauvarque C;Kumanogoh A;Camand E;Jaillard C

  • Tridimensional Visualization and Analysis of Early Human Development.

    Morgane Belle;David Godefroy;Gérard Couly;Samuel A. Malone

  • Slit-Robo signaling.

    Heike Blockus;Alain Chédotal

  • Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells.

    Sha Mi;Robert H. Miller;Wei Tang;Xinhua Lee

  • Spatiotemporal expression patterns of slit and robo genes in the rat brain.

    Valérie Marillat;Oliver Cases;Kim Tuyen Nguyen-Ba-Charvet;Marc Tessier-Lavigne

  • Regulation of cortical dendrite development by Slit-Robo interactions.

    Kristin L. Whitford;Valérie Marillat;Elke Stein;Corey S. Goodman

  • Neogenin mediates the action of repulsive guidance molecule.

    Srikanth Rajagopalan;Lutz Deitinghoff;Denise Davis;Sabine Conrad

  • RGM and its receptor neogenin regulate neuronal survival

    Eiji Matsunaga;Servane Tauszig-Delamasure;Philippe P. Monnier;Bernhard K. Mueller

  • Novel roles for Slits and netrins: axon guidance cues as anticancer targets?

    Patrick Mehlen;Céline Delloye-Bourgeois;Alain Chédotal

  • Slit2-Mediated Chemorepulsion and Collapse of Developing Forebrain Axons

    Kim Tuyen Nguyen Ba-Charvet;Katja Brose;Valérie Marillat;Tom Kidd

  • Directional guidance of oligodendroglial migration by class 3 semaphorins and netrin-1.

    Nathalie Spassky;Fernando de Castro;Barbara Le Bras;Katharina Heydon

  • Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor

    Véronique Corset;Kim Tuyen Nguyen-Ba-Charvet;Christelle Forcet;Emmanuel Moyse

  • Multiple Roles for Slits in the Control of Cell Migration in the Rostral Migratory Stream

    Kim T. Nguyen-Ba-Charvet;Nathalie Picard-Riera;Marc Tessier-Lavigne;Anne Baron-Van Evercooren

Frequent Co-Authors

Constantino Sotelo
Constantino Sotelo Sorbonne University
Marc Tessier-Lavigne
Marc Tessier-Lavigne Xaira Therapeutics
Isabelle Dusart
Isabelle Dusart Université Paris Cité
Paul J. Lockhart
Paul J. Lockhart Murdoch Children's Research Institute
Linda J. Richards
Linda J. Richards Washington University in St. Louis
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge
Aviv Regev
Aviv Regev Genentech
Zhigang He
Zhigang He Boston Children's Hospital
Alex L. Kolodkin
Alex L. Kolodkin Johns Hopkins University School of Medicine
Chris I. De Zeeuw
Chris I. De Zeeuw Erasmus University Rotterdam

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