World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
69
Citations
14932
World Ranking
2665
National Ranking
65

Biology and Biochemistry

D-Index
69
Citations
14985
World Ranking
7497
National Ranking
511

Overview

Yoshio Goshima is affiliated with Yokohama City University in Japan. Their research primarily focuses on the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology, with a specialized emphasis on Cellular and Molecular Neuroscience, Molecular Biology, Cell Biology, Developmental Neuroscience, and Neurology.

The main topics covered in their work include:

  • Axon Guidance and Neuronal Signaling
  • Receptor Mechanisms and Signaling
  • Neuroscience and Neuropharmacology Research
  • Neurogenesis and Neuroplasticity Mechanisms
  • Neurotransmitter Receptor Influence on Behavior
  • Biochemical Analysis and Sensing Techniques
  • Genetics and Neurodevelopmental Disorders

Their recent published papers include:

  • "Collapsin Response Mediator Proteins: Their Biological Functions and Pathophysiology in Neuronal Development and Regeneration," 2020, Frontiers in Cellular Neuroscience
  • "De Novo Truncating Variants in the Last Exon of SEMA6B Cause Progressive Myoclonic Epilepsy," 2020, The American Journal of Human Genetics
  • "Activity-induced secretion of semaphorin 3A mediates learning," 2021, European Journal of Neuroscience
  • "Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment," 2024, eLife
  • "Phosphorylation of Collapsin Response Mediator Protein 1 (CRMP1) at Tyrosine 504 residue regulates Semaphorin 3A-induced cortical dendritic growth," 2021, Journal of Neurochemistry

Frequent coauthors of Yoshio Goshima include:

  • Daiki Masukawa
  • Fumio Nakamura
  • Toshio Ohshima
  • Naoya Yamashita
  • Aoi Jitsuki-Takahashi

Their contributions have often appeared in publication venues such as:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Journal of Pharmacological Sciences
  • eLife
  • Brain Research
  • NeuroMolecular Medicine

Best Publications

  • Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33

    Yoshio Goshima;Yoshio Goshima;Fumio Nakamura;Philipp Strittmatter;Stephen M. Strittmatter

  • Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning.

    Makoto Nishiyama;Akemi Hoshino;Lily Tsai;John R. Henley

  • A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord

    Shinjiro Kaneko;Akio Iwanami;Masaya Nakamura;Akiyoshi Kishino

  • Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse.

    Hiroyuki Aizawa;Hiroyuki Aizawa;Shuji Wakatsuki;Ai Ishii;Kenji Moriyama

  • Phosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapse.

    Nariko Arimura;Naoyuki Inagaki;Kazuyasu Chihara;Céline Ménager

  • Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3β phosphorylation of CRMP2: Implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease

    Yutaka Uchida;Toshio Ohshima;Yukio Sasaki;Hiromi Suzuki

  • Fyn and Cdk5 Mediate Semaphorin-3A Signaling, Which Is Involved in Regulation of Dendrite Orientation in Cerebral Cortex

    Yukio Sasaki;Chi Cheng;Yutaka Uchida;Yutaka Uchida;Oumi Nakajima

  • Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones.

    Nariko Arimura;Céline Ménager;Yoji Kawano;Yoji Kawano;Takeshi Yoshimura

  • Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin.

    Mitsuharu Endo;Kazumasa Ohashi;Yukio Sasaki;Yoshio Goshima

  • Semaphorin3a Enhances Endocytosis at Sites of Receptor–F-Actin Colocalization during Growth Cone Collapse

    Alyson E. Fournier;Fumio Nakamura;Susumu Kawamoto;Yoshio Goshima

  • Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling.

    Asa Morita;Naoya Yamashita;Yukio Sasaki;Yutaka Uchida

  • Structural basis for semaphorin signalling through the plexin receptor.

    Terukazu Nogi;Norihisa Yasui;Norihisa Yasui;Emiko Mihara;Yukiko Matsunaga

  • Differential neurotoxicity induced by L-DOPA and dopamine in cultured striatal neurons.

    Neng-neng Cheng;Takehiko Maeda;Toshiaki Kume;Satoshi Kaneko

  • Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling

    Norihiro Mitsui;Ryoko Inatome;Shusuke Takahashi;Yoshio Goshima

  • Is l-dopa an endogenous neurotransmitter?

    Yoshimi Misu;Yoshio Goshima

  • Motor dysfunction in type 5 adenylyl cyclase-null mice.

    Tamio Iwamoto;Satoshi Okumura;Kousaku Iwatsubo;Jun-Ichi Kawabe

  • Evaluation of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 black mouse model for parkinsonism

    Nobutaka Arai;Kazuaki Misugi;Yoshio Goshima;Yoshimi Misu

  • Regulation of Spine Development by Semaphorin3A through Cyclin-Dependent Kinase 5 Phosphorylation of Collapsin Response Mediator Protein 1

    Naoya Yamashita;Asa Morita;Yutaka Uchida;Fumio Nakamura

  • Collapsin response mediator proteins regulate neuronal development and plasticity by switching their phosphorylation status.

    Naoya Yamashita;Yoshio Goshima

  • Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

    Brian T. D. Tobe;Brian T. D. Tobe;Andrew M. Crain;Alicia M. Winquist;Barbara Calabrese

  • Transmitter-Like Release of Endogenous 3,4-Dihydroxyphenylalanine from Rat Striatal Slices

    Y. Goshima;T. Kubo;Y. Misu

Frequent Co-Authors

Yoshimi Misu
Yoshimi Misu Yokohama City University
Toshio Ohshima
Toshio Ohshima Waseda University
Hiroshi Ueda
Hiroshi Ueda Kyoto University
Pappachan E. Kolattukudy
Pappachan E. Kolattukudy University of Central Florida
Itaru Endo
Itaru Endo Yokohama City University
Katsuhiko Mikoshiba
Katsuhiko Mikoshiba ShanghaiTech University
Evan Y. Snyder
Evan Y. Snyder Discovery Institute
Nobuhisa Mizuki
Nobuhisa Mizuki Yokohama City University
Jérôme Honnorat
Jérôme Honnorat Hospices Civils de Lyon

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