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Toshio Ohshima

Toshio Ohshima

D-Index & Metrics

Neuroscience

D-Index
50
Citations
9552
World Ranking
5729
National Ranking
182

Overview

Toshio Ohshima is affiliated with Waseda University in Japan and conducts research primarily within the fields of Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans multiple aspects of neuroscience, including cellular and molecular neuroscience, developmental neuroscience, molecular biology, cell biology, and physiology.

Their research topics cover a diverse range of subjects such as axon guidance and neuronal signaling, neurogenesis and neuroplasticity mechanisms, Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, zebrafish biomedical research applications, neuroscience and neuropharmacology research, and nerve injury and regeneration.

Recent papers by Toshio Ohshima include the following:

  • Recent Advances in the Modeling of Alzheimer's Disease, 2022, Frontiers in Neuroscience
  • Simple methods for the lesion detection and severity grading of diabetic retinopathy by image processing and transfer learning, 2021, Computers in Biology and Medicine
  • Collapsin Response Mediator Proteins: Their Biological Functions and Pathophysiology in Neuronal Development and Regeneration, 2020, Frontiers in Cellular Neuroscience
  • A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid β peptide, 2021, Journal of Biological Chemistry
  • An isogenic panel of App knock-in mouse models: Profiling β-secretase inhibition and endosomal abnormalities, 2022, Science Advances

Frequent coauthors include:

  • Yoshio Goshima
  • Takaomi C. Saido
  • Miyuki Takahashi
  • Naoto Watamura
  • Takashi Saito

Common publication venues for Toshio Ohshima's works are:

  • NeuroMolecular Medicine
  • Brain Research
  • Neurochemical Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Developmental Neurobiology

Best Publications

  • Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

    Toshio Ohshima;Jerrold M. Ward;Chang Goo Huh;Glenn Longenecker

  • α-Galactosidase A deficient mice: A model of Fabry disease

    Toshio Ohshima;Gary J. Murray;William D. Swaim;Glenn Longenecker

  • Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3β phosphorylation of CRMP2: Implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease

    Yutaka Uchida;Toshio Ohshima;Yukio Sasaki;Hiromi Suzuki

  • Fyn and Cdk5 Mediate Semaphorin-3A Signaling, Which Is Involved in Regulation of Dendrite Orientation in Cerebral Cortex

    Yukio Sasaki;Chi Cheng;Yutaka Uchida;Yutaka Uchida;Oumi Nakajima

  • Cyclin-Dependent Kinase 5-Deficient Mice Demonstrate Novel Developmental Arrest in Cerebral Cortex

    Edward C. Gilmore;Toshio Ohshima;André M. Goffinet;Ashok B. Kulkarni

  • Genomic Organization, Chromosomal Mapping, and Promoter Analysis of the Mouse Dentin Sialophosphoprotein (Dspp) Gene, Which Codes for Both Dentin Sialoprotein and Dentin Phosphoprotein

    Jian Q. Feng;Xianghong Luan;John Wallace;Dai Jing

  • Cdk5-dependent regulation of glucose-stimulated insulin secretion

    Fan Yan Wei;Kazuaki Nagashima;Toshio Ohshima;Yasunori Saheki

  • Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex.

    Toshio Ohshima;Motoyuki Hirasawa;Hidenori Tabata;Tetsuji Mutoh

  • Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous.

    Toshio Ohshima;Edward C. Gilmore;Glenn Longenecker;David M. Jacobowitz

  • Recent Advances in the Modeling of Alzheimer’s Disease

    Unknown

  • Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain.

    Toshio Ohshima;Masaharu Ogawa;Veeranna;Motoyuki Hirasawa

  • Characterization of neural stem cells and their progeny in the adult zebrafish optic tectum.

    Yoko Ito;Hideomi Tanaka;Hitoshi Okamoto;Toshio Ohshima

  • Regulation of Spine Development by Semaphorin3A through Cyclin-Dependent Kinase 5 Phosphorylation of Collapsin Response Mediator Protein 1

    Naoya Yamashita;Asa Morita;Yutaka Uchida;Fumio Nakamura

  • Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

    Brian T. D. Tobe;Brian T. D. Tobe;Andrew M. Crain;Alicia M. Winquist;Barbara Calabrese

  • Comparison of the effects of agalsidase alfa and agalsidase beta on cultured human Fabry fibroblasts and Fabry mice

    Hitoshi Sakuraba;Mai Murata-Ohsawa;Ikuo Kawashima;Youichi Tajima

  • Phosphorylation of CRMP2 (collapsin response mediator protein 2) is involved in proper dendritic field organization.

    Naoya Yamashita;Toshio Ohshima;Fumio Nakamura;Papachan Kolattukudy

  • A role for CA3 in social recognition memory.

    Ming Ching Chiang;Arthur J.Y. Huang;Marie E. Wintzer;Toshio Ohshima

  • Impairment of hippocampal long-term depression and defective spatial learning and memory in p35-/- mice

    Toshio Ohshima;Hiroo Ogura;Kazuhito Tomizawa;Kanehiro Hayashi

  • Collapsin Response Mediator Protein 1 Mediates Reelin Signaling in Cortical Neuronal Migration

    Naoya Yamashita;Yutaka Uchida;Toshio Ohshima;Syu Ichi Hirai

  • Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability.

    Fan Yan Wei;Kazuhito Tomizawa;Toshio Ohshima;Akiko Asada

  • Regulation of spine development by semaphorin3A through cyclin-dependent kinase 5 phosphorylation of collapsin response mediator protein 1 (Journal of Neuroscience (November 14, 2007) (12546-12554))

    Naoya Yamashita;Asa Morita;Yutaka Uchida;Fumio Nakamura

Frequent Co-Authors

Yoshio Goshima
Yoshio Goshima Yokohama City University
Takafumi Inoue
Takafumi Inoue Waseda University
Takaomi C. Saido
Takaomi C. Saido RIKEN Center for Brain Science
Kazunori Nakajima
Kazunori Nakajima Keio University
Karl Herrup
Karl Herrup Hong Kong University of Science and Technology
Takao K. Hensch
Takao K. Hensch Harvard University
Shigeyoshi Itohara
Shigeyoshi Itohara RIKEN Center for Brain Science
Mitsuharu Hattori
Mitsuharu Hattori Nagoya City University
Keigo Shibayama
Keigo Shibayama Nagoya University

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Related Online Degrees & Career Pathways

If you are considering a future in neuroscience, there are several related online degrees and career paths worth exploring. For those interested in the connection between the brain and behavior, enrolling in a psychology degree online can provide a solid foundation in understanding cognitive processes and mental health.

Students drawn to social support roles might consider an online master's in social work, which equips graduates to address neuropsychological issues in clinical and community settings. For those aiming to pursue advanced clinical practice, there are also excellent psyd programs online focused on clinical psychology and therapy.

Additionally, career pathways in marriage and family therapy are accessible through the mft program, paving the way for professionals interested in relationships and mental health. Each of these online degrees serves as a stepping stone to diverse roles within neuroscience, psychology, and counseling, making them valuable alternatives or complementary options for your academic and career journey.

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