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Biology and Biochemistry

D-Index
71
Citations
15023
World Ranking
6776
National Ranking
3136

Overview

Harish C. Pant is affiliated with the National Institutes of Health in the United States. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields including Genetics, Neurology, Molecular Biology, Physiology, and Nutrition and Dietetics.

The scientist's work focuses on several main topics, which include:

  • Trace Elements in Health
  • Alzheimer's disease research and treatments
  • Genomics and Rare Diseases
  • Genetics and Neurodevelopmental Disorders
  • Parkinson's Disease Mechanisms and Treatments
  • RNA regulation and disease
  • Autophagy in Disease and Therapy

Harish C. Pant has published extensively, with recent papers that include the following:

  • "IndiGenomes: a comprehensive resource of genetic variants from over 1000 Indian genomes" (2020) published in Nucleic Acids Research
  • "LncRNA VEAL2 regulates PRKCB2 to modulate endothelial permeability in diabetic retinopathy" (2021) published in The EMBO Journal
  • "Mitochondrial Dysfunction and Mitophagy Closely Cooperate in Neurological Deficits Associated with Alzheimer's Disease and Type 2 Diabetes" (2021) published in Molecular Neurobiology
  • "WilsonGen a comprehensive clinically annotated genomic variant resource for Wilson's Disease" (2020) published in Scientific Reports
  • "GPi-DBS for KMT2B-Associated Dystonia: Systematic Review and Meta-Analysis" (2021) published in Movement Disorders Clinical Practice

Frequent co-authors collaborating with Harish C. Pant include:

  • Vinod Scaria
  • Sangita Paul
  • Sridhar Sivasubbu
  • Juhi Bhardwaj
  • Mukesh Kumar

The common publication venues where Harish C. Pant's work appears are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Movement Disorders Clinical Practice
  • iScience
  • Nucleic Acids Research
  • The EMBO Journal

Best Publications

  • Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

    Toshio Ohshima;Jerrold M. Ward;Chang Goo Huh;Glenn Longenecker

  • Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression.

    Mark R. Hellmich;Harish C. Pant;Etsuko Wada;James F. Battey

  • Oxidative Stress in Neurodegeneration

    Varsha Shukla;Santosh K. Mishra;Harish C. Pant

  • Mitogen-Activated Protein Kinases (Erk1,2) Phosphorylate Lys-Ser-Pro (KSP) Repeats in Neurofilament Proteins NF-H and NF-M

    Veeranna;Niranjana D. Amin;Natalie G. Ahn;Howard Jaffe

  • Regulation of NMDA receptors by cyclin-dependent kinase-5.

    Bing-Sheng Li;Miao-Kun Sun;Lei Zhang;Satoru Takahashi

  • Differential expression of multiple transglutaminases in human brain. Increased expression and cross-linking by transglutaminases 1 and 2 in Alzheimer's disease.

    Soo-Youl Kim;Philip Grant;Jeung-Hoon Lee;Harish C. Pant

  • A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

    Gerardo Morfini;Gerardo Morfini;Györgyi Szebenyi;Hannah Brown;Harish C Pant

  • cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization.

    K T Shetty;W T Link;H C Pant

  • Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments.

    Ram K. Sihag;Masaki Inagaki;Tomoya Yamaguchi;Thomas B. Shea

  • A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons

    Ya-Li Zheng;Sashi Kesavapany;Maneth Gravell;Rebecca S Hamilton

  • The pathobiology of amyotrophic lateral sclerosis: a proteinopathy?

    Michael J Strong;Sashi Kesavapany;Harish C Pant

  • Neurofilament protein synthesis and phosphorylation

    Philip Grant;Harish C. Pant

  • Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway.

    Pushkar Sharma;Veeranna;Monica Sharma;Niranjana D. Amin

  • Acetylcholine stimulates cortical precursor cell proliferation in vitro via muscarinic receptor activation and MAP kinase phosphorylation.

    Wu Ma;Dragan Maric;Bing-sheng Li;Qian Hu

  • Cyclin-dependent Kinase-5 Is Involved in Neuregulin-dependent Activation of Phosphatidylinositol 3-Kinase and Akt Activity Mediating Neuronal Survival

    Bing-Sheng Li;Wu Ma;Howard Jaffe;Yali Zheng

  • Deregulated Cdk5 activity is involved in inducing Alzheimer's disease.

    Varsha Shukla;Susan Skuntz;Harish C. Pant

  • Cdk5 regulates the organization of Nestin and its association with p35.

    Cecilia M. Sahlgren;Andrey Mikhailov;Samuli Vaittinen;Hanna-Mari Pallari

  • Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3.

    Bing-Sheng Li;Lei Zhang;Satoru Takahashi;Wu Ma

  • Cyclin-dependent kinase 5 activity regulates pain signaling

    Tej K. Pareek;Jason Keller;Sashi Kesavapany;Harish C. Pant

  • Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: clinical implications for the nervous system response to glucocorticoids and stress.

    Tomoshige Kino;Takamasa Ichijo;Niranjana D. Amin;Sashi Kesavapany

Frequent Co-Authors

Ashok B. Kulkarni
Ashok B. Kulkarni National Institutes of Health
Roscoe O. Brady
Roscoe O. Brady Beth Israel Deaconess Medical Center
Toshio Ohshima
Toshio Ohshima Waseda University
Ram D. Sriram
Ram D. Sriram National Institute of Standards and Technology
Jeffery B. Klauda
Jeffery B. Klauda University of Maryland, College Park
Thomas B. Shea
Thomas B. Shea University of Massachusetts Lowell
Ralph A. Nixon
Ralph A. Nixon Nathan Kline Institute for Psychiatric Research
Michael J. Strong
Michael J. Strong University of Michigan–Ann Arbor
Michael J. Iadarola
Michael J. Iadarola National Institutes of Health
Barnett Rosenberg
Barnett Rosenberg Michigan State University

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