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Biology and Biochemistry

D-Index
68
Citations
16204
World Ranking
7802
National Ranking
3550

Overview

Thomas B. Shea is affiliated with the University of Massachusetts Lowell in the United States. Their research spans multiple disciplines with a primary focus on neuroscience, biochemistry, genetics, molecular biology, and environmental science.

Their main fields of study include:

  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology
  • Environmental Science

Subfields of research include:

  • Cellular and Molecular Neuroscience
  • Health, Toxicology and Mutagenesis
  • Cell Biology
  • Molecular Biology
  • Global and Planetary Change

Their work addresses a range of important topics such as:

  • Air Quality and Health Impacts
  • COVID-19 impact on air quality
  • Climate Change and Health Impacts
  • Alzheimer's disease research and treatments
  • Neurological Disease Mechanisms and Treatments
  • Antioxidant Activity and Oxidative Stress
  • Microtubule and mitosis dynamics

Recent published papers authored or co-authored by Thomas B. Shea include:

  • "Improvement of cognitive performance by a nutraceutical formulation: Underlying mechanisms revealed by laboratory studies", 2021, Free Radical Biology and Medicine
  • "An Overview of Studies Demonstrating that ex vivo Neuronal Networks Display Multiple Complex Behaviors: Emergent Properties of Nearest-Neighbor Interactions of Excitatory and Inhibitory Neurons.", 2021, The Open Neurology Journal

Other related publications connected with Shea's frequent collaborations are:

  • "Tau interferes with axonal neurite stabilization and cytoskeletal composition independently of its ability to associate with microtubules", 2020, Biology Open
  • "Synaptic Signals from Glutamate-Treated Neurons Induce Aberrant Post-Synaptic Signals in Untreated Neuronal Networks", 2020, The Open Neurology Journal

Frequent collaborators in their research include:

  • Sangmook Lee
  • Ekaterina Galkina Cleary
  • Manuel Cifuentes
  • Georges Grinstein
  • Doug Brugge

Key publication venues where Shea's work appears include:

  • The Open Neurology Journal
  • Free Radical Biology and Medicine
  • Biology Open

Best Publications

  • Palifermin for Oral Mucositis after Intensive Therapy for Hematologic Cancers

    Ricardo Spielberger;Patrick Stiff;William Bensinger;Teresa Gentile

  • Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.

    Mark P Mattson;Thomas B Shea

  • Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage.

    Pei I. Ho;Daniela Ortiz;Eugene Rogers;Thomas B. Shea

  • Homocysteine potentiates beta-amyloid neurotoxicity: role of oxidative stress.

    Pei I. Ho;Scott C. Collins;Sirikarnt Dhitavat;Daniela Ortiz

  • Textural studies of vesicles in volcanic rocks: An integrated methodology

    Thomas Shea;Bruce F. Houghton;Lucia Gurioli;Katharine V. Cashman

  • Calcium-Activated Neutral Proteinase (Calpain) System in Aging and Alzheimer's Diseasea

    R. A. Nixon;K.-I. Saito;F. Grynspan;W. R. Griffin

  • Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine.

    Pei I Ho;David Ashline;Sirikarnt Dhitavat;Daniela Ortiz

  • Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments.

    Ram K. Sihag;Masaki Inagaki;Tomoya Yamaguchi;Thomas B. Shea

  • Dynamics of neuronal intermediate filaments: a developmental perspective.

    Ralph A. Nixon;Thomas B. Shea

  • Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced neurodegeneration.

    Fatma J. Ekinci;Kafait U. Malik;Thomas B. Shea

  • Kinesin-mediated transport of neurofilament protein oligomers in growing axons

    Jason T. Yabe;Aurea Pimenta;Thomas B. Shea

  • Diffusion chronometry and the timescales of magmatic processes

    Fidel Costa;Thomas Shea;Teresa Ubide

  • Efficacy of a Vitamin/Nutriceutical Formulation for Moderate-stage to Later-stage Alzheimer's disease: A Placebo-controlled Pilot Study:

    Ruth Remington;Amy Chan;James Paskavitz;Thomas B. Shea

  • Efficacy of a vitamin/nutriceutical formulation for early-stage Alzheimer's disease: a 1-year, open-label pilot study with an 16-month caregiver extension.

    Amy Chan;James Paskavitz;Ruth Remington;Shelly Rasmussen

  • Phospholipid-mediated delivery of anti-GAP-43 antibodies into neuroblastoma cells prevents neuritogenesis.

    TB Shea;NI Perrone-Bizzozero;ML Beermann;LI Benowitz

  • Effect of retinoic acid on growth and morphological differentiation of mouse NB2a neuroblastoma cells in culture

    Thomas B. Shea;Itzhak Fischer;Victor S. Sapirstein

  • β-Amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation

    Fatma J Ekinci;Maria-Dawn Linsley;Thomas B Shea

  • Phospho-dependent association of neurofilament proteins with kinesin in situ.

    Jason T. Yabe;Cheolwha Jung;Walter K.-H. Chan;Thomas B. Shea

  • Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue.

    Thomas B Shea;Eugene Rogers;David Ashline;Daniela Ortiz

  • Neurofilaments Consist of Distinct Populations That Can Be Distinguished by C-Terminal Phosphorylation, Bundling, and Axonal Transport Rate in Growing Axonal Neurites

    Jason T. Yabe;Teresa Chylinski;Feng-Song Wang;Aurea Pimenta

Frequent Co-Authors

Ralph A. Nixon
Ralph A. Nixon Nathan Kline Institute for Psychiatric Research
Itzhak Fischer
Itzhak Fischer Drexel University
Jonathan S. Serody
Jonathan S. Serody University of North Carolina at Chapel Hill
Harish C. Pant
Harish C. Pant National Institutes of Health
Holly A. Yanco
Holly A. Yanco University of Massachusetts Lowell
Geoffrey R. Hill
Geoffrey R. Hill Fred Hutchinson Cancer Research Center
Kenneth S. Kosik
Kenneth S. Kosik University of California, Santa Barbara
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Larry I. Benowitz
Larry I. Benowitz Harvard Medical School
Eva-Maria Mandelkow
Eva-Maria Mandelkow German Center for Neurodegenerative Diseases

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