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Debomoy K. Lahiri

Debomoy K. Lahiri

D-Index & Metrics

Medicine

D-Index
96
Citations
34597
World Ranking
9644
National Ranking
4967

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Debomoy K. Lahiri is affiliated with Indiana University in the United States. Their research spans biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, physiology, cancer research, pharmacology, and cellular and molecular neuroscience. The primary topics covered in their work include microRNA in disease regulation, Alzheimer's disease research and treatments, RNA research and splicing, cholinesterase and neurodegenerative diseases, genetics and neurodevelopmental disorders, autism spectrum disorder research, and RNA interference and gene delivery.

Recent notable publications by Debomoy K. Lahiri include:

  • MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties, 2020, Molecular Psychiatry
  • Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease, 2020, Translational Psychiatry
  • Human microRNA (miR-20b-5p) modulates Alzheimer's disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer's biomarkers, 2022, Molecular Psychiatry
  • Synaptosome microRNAs regulate synapse functions in Alzheimer's disease, 2022, npj Genomic Medicine
  • Repeated electromagnetic field stimulation lowers amyloid-β peptide levels in primary human mixed brain tissue cultures, 2021, Scientific Reports

Lahiri has frequently published in several scientific venues, including:

  • Alzheimer s & Dementia
  • Molecular Psychiatry
  • Scientific Reports
  • Ageing Research Reviews
  • Current Alzheimer Research

Collaborations have been a consistent feature of Lahiri's work, with frequent co-authors such as Bryan Maloney, Nigel H. Greig, Ruizhi Wang, Scott Counts, and Kumar Sambamurti. These partnerships have contributed to advancing research particularly in the Alzheimer's disease domain and related fields.

Debomoy K. Lahiri's research contributes broadly to understanding molecular mechanisms underlying neurodegenerative disorders, with a particular emphasis on Alzheimer's disease and microRNA regulation. Their work integrates genetic, molecular, and pharmacological perspectives to explore disease pathways, potential treatments, and biomarker influences.

In 2020, Lahiri was recognized as a Fellow of the American Association for the Advancement of Science (AAAS), indicating a role within the scientific community that supports the advancement of science and research.

Best Publications

  • Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain.

    Angelica Becaria;Debomoy K. Lahiri;Stephen C. Bondy;De Mao Chen

  • A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies

    D K Lahiri;J I Nurnberger

  • Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent

    Nigel H. Greig;Tadanobu Utsuki;Tadanobu Utsuki;Donald K. Ingram;Yue Wang

  • GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

    Yazhou Li;Tracy Ann Perry;Mark S. Kindy;Brandon K. Harvey

  • An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript.

    Jack T. Rogers;Jeffrey D. Randall;Catherine M. Cahill;Paul S. Eder

  • Butyrylcholinesterase: an important new target in Alzheimer's disease therapy.

    Nigel H. Greig;Debomoy K. Lahiri;Kumar Sambamurti

  • Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD

    Jinfang Wu;Md. Riyaz Basha;Brian Brock;David P. Cox

  • A new therapeutic target in Alzheimer's disease treatment: attention to butyrylcholinesterase.

    Nigel H. Greig;Tada Utsuki;Qian-sheng Yu;Xiaoxiang Zhu

  • Epigenetics, oxidative stress, and Alzheimer disease.

    Nasser H. Zawia;Debomoy K. Lahiri;Fernando Cardozo-Pelaez

  • Glucagon-like peptide-1 decreases endogenous amyloid-β peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron

    Tracy Ann Perry;Debomoy K. Lahiri;Kumar Sambamurti;Demao Chen

  • The Fetal Basis of Amyloidogenesis: Exposure to Lead and Latent Overexpression of Amyloid Precursor Protein and β-Amyloid in the Aging Brain

    M. Riyaz Basha;Wei Wei;Saleh A. Bakheet;Nathalie Benitez

  • N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer's disease, vascular dementia and Parkinson's disease.

    David Olivares;Varun K. Deshpande;Ying Shi;Debomoy K. Lahiri

  • GLP-1 Receptor Stimulation Reduces Amyloid-β Peptide Accumulation and Cytotoxicity in Cellular and Animal Models of Alzheimer's Disease

    Yazhou Li;Kara B. Duffy;Mary Ann Ottinger;Balmiki Ray

  • Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer's Disease

    Robert J. Baranello;Krishna L. Bharani;Vasudevaraju Padmaraju;Nipun Chopra

  • Targeting Tumor Necrosis Factor Alpha for Alzheimer's Disease.

    Boris Decourt;Debomoy K Lahiri;Marwan N Sabbagh

  • A Novel Neurotrophic Property of Glucagon-Like Peptide 1: A Promoter of Nerve Growth Factor-Mediated Differentiation in PC12 Cells

    Tracyann Perry;Debomoy K. Lahiri;Demao Chen;J. I.E. Zhou

  • DNA isolation by a rapid method from human blood samples: Effects of MgCl2, EDTA, storage time, and temperature on DNA yield and quality

    Debomoy K. Lahiri;Bill Schnabel

  • Melatonin Suppression by Light in Euthymic Bipolar and Unipolar Patients

    John I. Nurnberger;Sherril Adkins;Debomoy K. Lahiri;Aimee Mayeda;Aimee Mayeda

  • Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer’s disease

    Kumar Sambamurti;Nigel H. Greig;Debomoy K. Lahiri

  • A non-organic and non-enzymatic extraction method gives higher yields of genomic DNA from whole-blood samples than do nine other methods tested.

    Debomoy K. Lahiri;Steve Bye;John I. Nurnberger;Marion E. Hodes

Frequent Co-Authors

Nigel H. Greig
Nigel H. Greig National Institutes of Health
Kumar Sambamurti
Kumar Sambamurti Medical University of South Carolina
Jack T. Rogers
Jack T. Rogers Harvard University
Martin R. Farlow
Martin R. Farlow Indiana University
John I. Nurnberger
John I. Nurnberger Indiana University
Xudong Huang
Xudong Huang Harvard University
Donald K. Ingram
Donald K. Ingram Louisiana State University
Stephen C. Bondy
Stephen C. Bondy University of California, Irvine
Catherine M. Cahill
Catherine M. Cahill University of California, Los Angeles
Weihong Song
Weihong Song University of British Columbia

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