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Biology and Biochemistry

D-Index
61
Citations
11706
World Ranking
11484
National Ranking
4962

Overview

Jack T. Rogers is affiliated with Harvard University in the United States. Their research primarily focuses on medicine, with specific attention to molecular biology, nutrition and dietetics, neurology, physiology, and cellular and molecular neuroscience.

The main topics covered in their work include:

  • Trace Elements in Health
  • Alzheimer's disease research and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Heavy Metal Exposure and Toxicity
  • RNA regulation and disease
  • RNA Research and Splicing
  • Nuclear Receptors and Signaling

Jack T. Rogers has contributed to several scientific publications. Notable recent papers include:

  • "Biomarkers of environmental manganese exposure and associations with childhood neurodevelopment: a systematic review and meta-analysis" (2020), published in Environmental Health
  • "Iron-responsive-like elements and neurodegenerative ferroptosis" (2020), published in Learning & Memory
  • "Targeting PSEN1 by lnc-CYP3A43-2/miR-29b-2-5p to Reduce β Amyloid Plaque Formation and Improve Cognition Function" (2022), published in International Journal of Molecular Sciences
  • "Exposure to CuO Nanoparticles Mediates NFκB Activation and Enhances Amyloid Precursor Protein Expression" (2020), published in Biomedicines
  • "How autism and Alzheimer's disease are TrAPPed" (2020), published in Molecular Psychiatry

Frequent publication venues for their work include:

  • Biomolecules
  • Journal of Alzheimer s Disease
  • Circulation
  • Environmental Health
  • Learning & Memory

The scientist has collaborated regularly with several coauthors, including:

  • Catherine M. Cahill
  • Alexander Pilozzi
  • Xudong Huang
  • Debomoy K. Lahiri

Best Publications

  • Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

    James A. Duce;Andrew Tsatsanis;Michael A. Cater;Simon A. James

  • An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript.

    Jack T. Rogers;Jeffrey D. Randall;Catherine M. Cahill;Paul S. Eder

  • Redox-active metals, oxidative stress, and Alzheimer's disease pathology.

    Xudong Huang;Robert D. Moir;Rudolph E. Tanzi;Ashley I. Bush

  • N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer's disease, vascular dementia and Parkinson's disease.

    David Olivares;Varun K. Deshpande;Ying Shi;Debomoy K. Lahiri

  • Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.

    Jack T. Rogers;Lorene M. Leiter;Jay McPhee;Catherine M. Cahill

  • Iron-dependent regulation of the divalent metal ion transporter

    Hiromi Gunshin;Hiromi Gunshin;Charles R. Allerson;Maria Polycarpou-Schwarz;Andreas Rofts

  • Translational control during the acute phase response. Ferritin synthesis in response to interleukin-1.

    J T Rogers;K R Bridges;G P Durmowicz;J Glass

  • Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation

    Andrew M Thomson;Jack T Rogers;Peter J Leedman

  • Interleukin (IL) 1β Induction of IL-6 Is Mediated by a Novel Phosphatidylinositol 3-Kinase-dependent AKT/IκB Kinase α Pathway Targeting Activator Protein-1

    Catherine M. Cahill;Jack T. Rogers

  • Phenserine regulates translation of β-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development

    Karen T. Y. Shaw;Tadanobu Utsuki;Jack Rogers;Qian-Sheng Yu

  • MicroRNAs can regulate human APP levels

    Neha Patel;David Hoang;Nathan Miller;Sara Ansaloni

  • Selective Translational Control of the Alzheimer Amyloid Precursor Protein Transcript by Iron Regulatory Protein-1

    Hyun Hee Cho;Catherine M. Cahill;Charles R. Vanderburg;Clemens R. Scherzer

  • High prevalence of abnormal glucose homeostasis secondary to decreased insulin secretion in individuals with hereditary haemochromatosis

    D. A. McClain;D. Abraham;J. Rogers;R. Brady

  • Translation of ferritin light and heavy subunit mRNAs is regulated by intracellular chelatable iron levels in rat hepatoma cells

    Jack Rogers;Hamish Munro

  • Ferritin translation by interleukin-6: the role of sequences upstream of the start codons of the heavy and light subunit genes

    JT Rogers

  • Brain Iron Metabolism Dysfunction in Parkinson’s Disease

    Hong Jiang;Jun Wang;Jack Rogers;Junxia Xie

  • The 5′-untranslated region of Parkinson's disease α -synuclein messengerRNA contains a predicted iron responsive element

    A L Friedlich;R E Tanzi;J T Rogers

  • Metal and inflammatory targets for Alzheimer's disease.

    Jack T Rogers;Debomoy K Lahiri

  • Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis.

    Alpaslan Dedeoglu;Kerry Cormier;Kerry Cormier;Sandra Payton;Katya A. Tseitlin

  • Metal exposure and Alzheimer's pathogenesis.

    Guijian Liu;Weidong Huang;Robert D. Moir;Charles R. Vanderburg

Frequent Co-Authors

Xudong Huang
Xudong Huang Harvard University
Catherine M. Cahill
Catherine M. Cahill University of California, Los Angeles
Debomoy K. Lahiri
Debomoy K. Lahiri Indiana University
Ashley I. Bush
Ashley I. Bush Florey Institute of Neuroscience and Mental Health
Nigel H. Greig
Nigel H. Greig National Institutes of Health
Rudolph E. Tanzi
Rudolph E. Tanzi Harvard University
Robert D. Moir
Robert D. Moir Harvard University
Fudi Wang
Fudi Wang Zhejiang University
Kumar Sambamurti
Kumar Sambamurti Medical University of South Carolina
Ronald C. Petersen
Ronald C. Petersen University of Pennsylvania

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