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Medicine

D-Index
102
Citations
37768
World Ranking
7669
National Ranking
3991

Overview

Nigel H. Greig is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience, contributing extensively to understanding various aspects of neurobiology and related diseases.

The main subfields of their work include Molecular Biology, Neurology, Physiology, Cellular and Molecular Neuroscience, and Pharmacology. These areas support their in-depth exploration of complex biological mechanisms and their implications for brain health and disease.

The topics frequently addressed by their research involve:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Protein Degradation and Inhibitors
  • Neuroscience and Neuropharmacology Research
  • Multiple Myeloma Research and Treatments
  • Tryptophan and brain disorders

Greig has published extensively in several scientific journals, with a notable presence in:

  • Alzheimer's & Dementia
  • Current Neuropharmacology
  • Scientific Reports
  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent published papers include:

  • Glucagon-like peptide-1 (GLP-1) receptor agonists and neuroinflammation: Implications for neurodegenerative disease treatment, 2022, Pharmacological Research
  • Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis, 2022, Alzheimer's & Dementia
  • The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial, 2023, Brain
  • Inhibition of Caspase 3 and Caspase 9 Mediated Apoptosis: A Multimodal Therapeutic Target in Traumatic Brain Injury, 2022, Current Neuropharmacology
  • Cytokine Imbalance in Schizophrenia. From Research to Clinic: Potential Implications for Treatment, 2021, Frontiers in Psychiatry

Frequent collaborators in Greig's work include:

  • David Tweedie
  • Barry J. Hoffer
  • Yazhou Li
  • Debomoy K. Lahiri
  • Weiming Luo

Best Publications

  • Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

    E F Fang;Y Hou;K Palikaras;B A Adriaanse

  • Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial

    Dilan Athauda;Kate Maclagan;Simon S Skene;Martha Bajwa-Joseph

  • Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent

    Nigel H. Greig;Tadanobu Utsuki;Tadanobu Utsuki;Donald K. Ingram;Yue Wang

  • Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms

    Jesse S. Kerr;Bryan A. Adriaanse;Nigel H. Greig;Mark P. Mattson;Mark P. Mattson

  • GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

    Yazhou Li;Tracy Ann Perry;Mark S. Kindy;Brandon K. Harvey

  • An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript.

    Jack T. Rogers;Jeffrey D. Randall;Catherine M. Cahill;Paul S. Eder

  • Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function.

    Hyo Youl Moon;Andreas Becke;David Berron;Benjamin Becker

  • Butyrylcholinesterase: an important new target in Alzheimer's disease therapy.

    Nigel H. Greig;Debomoy K. Lahiri;Kumar Sambamurti

  • Drug discovery and development: Role of basic biological research.

    Richard C. Mohs;Nigel H. Greig

  • A new therapeutic target in Alzheimer's disease treatment: attention to butyrylcholinesterase.

    Nigel H. Greig;Tada Utsuki;Qian-sheng Yu;Xiaoxiang Zhu

  • Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4

    TracyAnn Perry;Norman J. Haughey;Mark P. Mattson;Josephine M. Egan

  • Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats.

    Margarzata Szayna;Máire E. Doyle;Jennifer A. Betkey;Harold W. Holloway

  • Glucagon-like peptide-1 decreases endogenous amyloid-β peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron

    Tracy Ann Perry;Debomoy K. Lahiri;Kumar Sambamurti;Demao Chen

  • Cholinesterases: Roles in the Brain During Health and Disease

    Clive G. Ballard;Nigel H. Greig;Angela L. Guillozet-Bongaarts;Albert Enz

  • N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer's disease, vascular dementia and Parkinson's disease.

    David Olivares;Varun K. Deshpande;Ying Shi;Debomoy K. Lahiri

  • GLP-1 Receptor Stimulation Reduces Amyloid-β Peptide Accumulation and Cytotoxicity in Cellular and Animal Models of Alzheimer's Disease

    Yazhou Li;Kara B. Duffy;Mary Ann Ottinger;Balmiki Ray

  • A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

    Carsten Culmsee;Xiaoxiang Zhu;Qian Sheng Yu;Sic L. Chan

  • Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer's Disease

    Robert J. Baranello;Krishna L. Bharani;Vasudevaraju Padmaraju;Nipun Chopra

  • A Novel Neurotrophic Property of Glucagon-Like Peptide 1: A Promoter of Nerve Growth Factor-Mediated Differentiation in PC12 Cells

    Tracyann Perry;Debomoy K. Lahiri;Demao Chen;J. I.E. Zhou

  • TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation

    Karim Belarbi;Timothy Jopson;David Tweedie;Carla Arellano

Frequent Co-Authors

Debomoy K. Lahiri
Debomoy K. Lahiri Indiana University
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Kumar Sambamurti
Kumar Sambamurti Medical University of South Carolina
Mohammad A. Kamal
Mohammad A. Kamal Princess Nourah bint Abdulrahman University
Stanley I. Rapoport
Stanley I. Rapoport National Institutes of Health
Chaim G. Pick
Chaim G. Pick Tel Aviv University
Donald K. Ingram
Donald K. Ingram Louisiana State University
Jack T. Rogers
Jack T. Rogers Harvard University
Dimitrios Kapogiannis
Dimitrios Kapogiannis National Institutes of Health
Josephine M. Egan
Josephine M. Egan National Institutes of Health

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