H-Index & Metrics Top Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Medicine H-index 181 Citations 127,739 1,393 World Ranking 117 National Ranking 1

Research.com Recognitions

Awards & Achievements

2021 - Canada Gairdner International Award

2020 - Warren Alpert Foundation Prize For identifying Glucagon-like peptides and leading the field with studies extending from cells to humans, culminating in the development of these peptides as therapeutic agents for treating diabetes and short bowel syndrome.

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Endocrinology
  • Diabetes mellitus

His primary scientific interests are in Internal medicine, Endocrinology, Glucagon-like peptide-1, Insulin and Glucagon. His work in Postprandial, Gastric emptying, Glucagon secretion, Gastrointestinal hormone and Hormone is related to Internal medicine. His research investigates the connection between Postprandial and topics such as Appetite that intersect with issues in Ghrelin.

His study involves Incretin, Diabetes mellitus, Type 2 diabetes, Pancreatic hormone and Gastric inhibitory polypeptide, a branch of Endocrinology. His research integrates issues of Small intestine, Secretion, Somatostatin, Peptide and Dipeptidyl peptidase in his study of Glucagon-like peptide-1. His research investigates the link between Glucagon and topics such as Proglucagon that cross with problems in Glucagon-like peptide-2, Enteroglucagon and Receptor.

His most cited work include:

  • The Physiology of Glucagon-like Peptide 1 (2106 citations)
  • Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. (1309 citations)
  • Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study (1213 citations)

What are the main themes of his work throughout his whole career to date?

Jens J. Holst spends much of his time researching Internal medicine, Endocrinology, Insulin, Glucagon and Glucagon-like peptide-1. Jens J. Holst combines subjects such as Diabetes mellitus and Type 2 diabetes with his study of Internal medicine. Jens J. Holst has included themes like Weight loss and Type 2 Diabetes Mellitus in his Type 2 diabetes study.

His studies link Gastric emptying with Endocrinology. His Glucagon research is multidisciplinary, relying on both Glucagon-like peptide-2, Proglucagon, Somatostatin and Peptide hormone. His Glucagon-like peptide-1 research is multidisciplinary, incorporating perspectives in Gastrointestinal hormone and Receptor.

He most often published in these fields:

  • Internal medicine (89.29%)
  • Endocrinology (83.20%)
  • Insulin (30.59%)

What were the highlights of his more recent work (between 2018-2021)?

  • Internal medicine (89.29%)
  • Endocrinology (83.20%)
  • Glucagon (28.70%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Internal medicine, Endocrinology, Glucagon, Postprandial and Insulin. His Internal medicine research includes elements of Diabetes mellitus, Type 2 diabetes and Crossover study. The Type 1 diabetes and Hypoglycemia research Jens J. Holst does as part of his general Diabetes mellitus study is frequently linked to other disciplines of science, such as In patient, therefore creating a link between diverse domains of science.

While the research belongs to areas of Endocrinology, Jens J. Holst spends his time largely on the problem of Receptor, intersecting his research to questions surrounding Pharmacology. The concepts of his Postprandial study are interwoven with issues in Meal, Gastric emptying, Weight loss, Bile acid and Glycemic. His biological study focuses on Insulin resistance.

Between 2018 and 2021, his most popular works were:

  • Glucagon-like peptide 1 (GLP-1) (164 citations)
  • Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial (115 citations)
  • Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial (115 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Endocrinology
  • Diabetes mellitus

His primary areas of study are Internal medicine, Endocrinology, Glucagon, Postprandial and Hormone. His research on Internal medicine focuses in particular on Insulin. His Endocrinology study integrates concerns from other disciplines, such as Receptor and Antagonist.

His research in Glucagon focuses on subjects like Alpha cell, which are connected to Lipid metabolism. His Postprandial research also works with subjects such as

  • Weight loss which is related to area like Glycemic,
  • Gastric emptying and related Carbohydrate metabolism. Jens J. Holst interconnects Peptide YY and Glucose homeostasis in the investigation of issues within Hormone.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Top Publications

The Physiology of Glucagon-like Peptide 1

Jens Juul Holst.
Physiological Reviews (2007)

2897 Citations

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.

M A Nauck;M M Heimesaat;C Orskov;J J Holst.
Journal of Clinical Investigation (1993)

1727 Citations

Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study

Mette Zander;Mette Zander;Sten Madsbad;Jan Lysgaard Madsen;Jens Juul Holst.
The Lancet (2002)

1624 Citations

Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans.

A Flint;A Raben;A Astrup;J J Holst.
Journal of Clinical Investigation (1998)

1520 Citations

Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.

M. A. Nauck;N. Kleine;C. Orskov;J. J. Holst.
Diabetologia (1993)

1282 Citations

Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients.

Mai-Britt Toft-Nielsen;Mette B. Damholt;Sten Madsbad;Linda M. Hilsted.
The Journal of Clinical Endocrinology and Metabolism (2001)

1108 Citations

Reduced Postprandial Concentrations of Intact Biologically Active Glucagon-Like Peptide 1 in Type 2 Diabetic Patients

Tina Vilsbøll;Thure Krarup;Carolyn F. Deacon;Sten Madsbad.
Diabetes (2001)

1084 Citations

Both Subcutaneously and Intravenously Administered Glucagon-Like Peptide I Are Rapidly Degraded From the NH2-Terminus in Type II Diabetic Patients and in Healthy Subjects

Carolyn F Deacon;Michael A Nauck;Maibritt Toft-Nielsen;Lone Pridal.
Diabetes (1995)

1062 Citations

Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus.

M Gutniak;C Orskov;J J Holst;B Ahrén.
The New England Journal of Medicine (1992)

1059 Citations

Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans

Michael A. Nauck;Ulrich Niedereichholz;Rainer Ettler;Jens Juul Holst.
American Journal of Physiology-endocrinology and Metabolism (1997)

1022 Citations

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking h-index is inferred from publications deemed to belong to the considered discipline.

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