World's Best Scientists 2026 revealed!
Award Badge
Best Scientists
2025
Award Badge
Medicine
Denmark
2026

D-Index & Metrics

Best Scientists

D-Index
201
Citations
160195
World Ranking
283
National Ranking
2

Medicine

D-Index
206
Citations
165847
World Ranking
146
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Medicine in Denmark Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in Denmark Leader Award
  • 2023 - Research.com Medicine in Denmark Leader Award
  • 2022 - Research.com Medicine in Denmark Leader Award
  • 2021 - Canada Gairdner International Award
  • 2020 - Warren Alpert Foundation Prize For identifying Glucagon-like peptides and leading the field with studies extending from cells to humans, culminating in the development of these peptides as therapeutic agents for treating diabetes and short bowel syndrome.

Overview

Jens J. Holst is affiliated with the University of Copenhagen in Denmark. Their research primarily focuses on medicine, with a significant number of publications in the field of endocrinology, diabetes, and metabolism. Holst has contributed extensively to subfields including Endocrinology, Diabetes and Metabolism, Surgery, Physiology, Molecular Biology, and Endocrine and Autonomic Systems.

The scientist's work covers several main topics, notably Diabetes Treatment and Management, Diet and Metabolism Studies, Pancreatic Function and Diabetes, Metabolism, Diabetes, and Cancer, Diabetes Management and Research, Bariatric Surgery and Outcomes, and Diet, Metabolism, and Disease.

Holst frequently publishes in specialized journals, with notable venues including Diabetes Obesity and Metabolism, The Journal of Clinical Endocrinology & Metabolism, Diabetes, Diabetologia, and the European Journal of Endocrinology.

Among recent papers authored or co-authored by Holst are:

  • "Statin therapy is associated with lower prevalence of gut microbiota dysbiosis," 2020, Nature
  • "Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist," 2020, JCI Insight
  • "Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined," 2021, New England Journal of Medicine
  • "Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology," 2020, Nature Communications
  • "Combinatorial, additive and dose-dependent drug-microbiome associations," 2021, Nature

Frequent collaborators include Bolette Hartmann, Filip K. Knop, Sten Madsbad, Nicolai J. Wewer Albrechtsen, and Tina Vilsbøll.

Jens J. Holst has received recognitions such as the Canada Gairdner International Award in 2021 and the Warren Alpert Foundation Prize in 2020. The latter was awarded for contributions to the identification of Glucagon-like peptides and leading studies spanning from cellular research to therapeutic applications for diabetes and short bowel syndrome.

Best Publications

  • The Physiology of Glucagon-like Peptide 1

    Jens Juul Holst

  • Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.

    M A Nauck;M M Heimesaat;C Orskov;J J Holst

  • Type 2 diabetes mellitus.

    Ralph A. DeFronzo;Ele Ferrannini;Leif Groop;Robert R. Henry

  • Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study

    Mette Zander;Mette Zander;Sten Madsbad;Jan Lysgaard Madsen;Jens Juul Holst

  • Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans.

    A Flint;A Raben;A Astrup;J J Holst

  • Glucagon-like peptide 1 (GLP-1)

    T.D. Müller;B. Finan;S.R. Bloom;D. D'Alessio

  • Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1(7-36)amide in type 2 (non-insulin-dependent) diabetic patients

    M. A. Nauck;N. Kleine;C. Orskov;J. J. Holst

  • Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients.

    Mai-Britt Toft-Nielsen;Mette B. Damholt;Sten Madsbad;Linda M. Hilsted

  • Reduced Postprandial Concentrations of Intact Biologically Active Glucagon-Like Peptide 1 in Type 2 Diabetic Patients

    Tina Vilsbøll;Thure Krarup;Carolyn F. Deacon;Sten Madsbad

  • Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations.

    Ewan R Pearson;Isabelle Flechtner;Pål R Njølstad;Maciej T Malecki

  • Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans

    Michael A. Nauck;Ulrich Niedereichholz;Rainer Ettler;Jens Juul Holst

  • Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus.

    M Gutniak;C Orskov;J J Holst;B Ahrén

  • Both Subcutaneously and Intravenously Administered Glucagon-Like Peptide I Are Rapidly Degraded From the NH2-Terminus in Type II Diabetic Patients and in Healthy Subjects

    Carolyn F Deacon;Michael A Nauck;Maibritt Toft-Nielsen;Lone Pridal

  • Inhibition of gastric inhibitory polypeptide signaling prevents obesity.

    Kazumasa Miyawaki;Yuichiro Yamada;Nobuhiro Ban;Yu Ihara

  • Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo

    C F Deacon;A H Johnsen;J J Holst

  • Tissue and Plasma Concentrations of Amidated and Glycine-Extended Glucagon-Like Peptide I in Humans

    Cathrine Ørskov;Lise Rabenhøj;André Wettergren;Hans Kofod

  • Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition

    Ruud S. Kootte;Evgeni Levin;Jarkko Salojärvi;Loek P. Smits

  • Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man.

    André Wettergren;Birgit Schjoldager;Poul Erik Mortensen;John Myhre

  • Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans.

    Jens Juul Holst;Jesper Gromada

  • Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease

    Thomas Nyström;Mark K. Gutniak;Qimin Zhang;Fan Zhang

Frequent Co-Authors

Filip K. Knop
Filip K. Knop University of Copenhagen
Sten Madsbad
Sten Madsbad University of Copenhagen
Carolyn F. Deacon
Carolyn F. Deacon University of Copenhagen
Jens F. Rehfeld
Jens F. Rehfeld University of Copenhagen
Steen Seier Poulsen
Steen Seier Poulsen University of Copenhagen
Torben Hansen
Torben Hansen University of Copenhagen
Arne Astrup
Arne Astrup Novo Nordisk Foundation
Mette M. Rosenkilde
Mette M. Rosenkilde University of Copenhagen
Michael A. Nauck
Michael A. Nauck Ruhr University Bochum
Oluf Pedersen
Oluf Pedersen University of Copenhagen

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring online degrees in healthcare can open flexible and dynamic career options beyond becoming a doctor. For those interested in patient care and looking for accessible entry points, consider reviewing easy nursing programs to get into, which often offer less competitive admissions and faster pathways to nursing credentials.

If you are interested in administrative roles, accredited medical billing and coding schools with financial aid provide an affordable route into the health information management field. These programs can be completed online and are in high demand.

Worried about admissions testing? Not all schools require major entrance exams. Check out the guide, do all nursing schools require the teas, for programs that waive these common requirements.

For those interested in leadership, healthcare administration programs offer a fast-track to management and policy roles in hospitals, clinics, and health systems—all through online education.

Best Scientists Citing Jens J. Holst

Trending Scientists