World's Best Scientists 2026 revealed!
David A. D'Alessio

David A. D'Alessio

D-Index & Metrics

Medicine

D-Index
102
Citations
43401
World Ranking
7590
National Ranking
3957

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

David A. D'Alessio is affiliated with Duke University in the United States, focusing their research on medicine, particularly endocrinology, diabetes, and metabolism. Their work covers multiple subfields including surgery, physiology, molecular biology, and genetics.

Their primary research topics revolve around diabetes treatment and management, pancreatic function and diabetes, diet and metabolism studies, diabetes management and research, diabetes and associated disorders, receptor mechanisms and signaling, and pharmacology and obesity treatment.

Key publications by David A. D'Alessio include:

  • "Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist," 2020, JCI Insight
  • "LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial," 2022, The Lancet
  • "Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS-CVOT design and baseline characteristics," 2023, American Heart Journal
  • "GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells," 2021, Science Advances
  • "Erratum. 2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2020;43:487-493," 2020, Diabetes Care

Frequent co-authors in their research collaborations include:

  • Jonathan E. Campbell
  • Steven E. Kahn
  • Megan E. Capozzi
  • Sarah M. Gray
  • Kyle W. Sloop

David A. D'Alessio has published extensively across several scientific journals. Their most common publication venues are:

  • Diabetes
  • Diabetes Care
  • Journal of the Endocrine Society
  • Diabetologia
  • Science Advances

Their research contributes significantly to understanding complex biological and clinical aspects of diabetes and metabolic disorders. David A. D'Alessio is recognized as a member of the Association of American Physicians.

Best Publications

  • Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

    Melanie J. Davies;David A. D’Alessio;Judith Fradkin;Walter N. Kernan

  • Glucagon-like peptide 1 (GLP-1)

    T.D. Müller;B. Finan;S.R. Bloom;D. D'Alessio

  • Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

    Melanie J. Davies;Melanie J. Davies;David A. D’Alessio;Judith Fradkin;Walter N. Kernan

  • A Randomized Trial Comparing a Very Low Carbohydrate Diet and a Calorie-Restricted Low Fat Diet on Body Weight and Cardiovascular Risk Factors in Healthy Women

    Bonnie J. Brehm;Randy J. Seeley;Stephen R. Daniels;David A. D’Alessio

  • Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women.

    Karen L Teff;Sharon S Elliott;Matthias Tschöp;Timothy J Kieffer

  • Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1

    Sung Hee Um;David D'Alessio;David D'Alessio;George Thomas

  • A Controlled High-Fat Diet Induces an Obese Syndrome in Rats

    Stephen C. Woods;Randy J. Seeley;Paul A. Rushing;David D’Alessio

  • Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis.

    Mercedes Falciglia;Ron W. Freyberg;Peter L. Almenoff;David A. D’Alessio

  • Evidence of Cosecretion of Islet Amyloid Polypeptide and Insulin by β-Cells

    Steven E Kahn;David A D'Alessio;Michael W Schwartz;Wilfred Y Fujimoto

  • LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.

    Tamer Coskun;Kyle W. Sloop;Corina Loghin;Jorge Alsina-Fernandez

  • Central Control of Body Weight and Appetite

    Stephen C. Woods;David A. D'Alessio

  • A reappraisal of the caloric requirements of men.

    O E Owen;J L Holup;D A D'Alessio;E S Craig

  • Physiology of Proglucagon Peptides: Role of Glucagon and GLP-1 in Health and Disease

    Darleen A. Sandoval;David A. D'Alessio

  • Effects of a fixed meal pattern on ghrelin secretion: evidence for a learned response independent of nutrient status

    Deborah L. Drazen;Torsten P. Vahl;David A. D’Alessio;Randy J. Seeley

  • Cloned mice have an obese phenotype not transmitted to their offspring

    Kellie L.K. Tamashiro;Teruhiko Wakayama;Hidenori Akutsu;Yukiko Yamazaki

  • Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans

    Jenny Tong;Ronald L. Prigeon;Harold W. Davis;Martin Bidlingmaier

  • Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal.

    D A D'Alessio;S E Kahn;C R Leusner;J W Ensinck

  • Weight loss through ileal transposition is accompanied by increased ileal hormone secretion and synthesis in rats

    April D. Strader;Torsten P. Vahl;Ronald J. Jandacek;Stephen C. Woods

  • Cooperation between brain and islet in glucose homeostasis and diabetes

    Michael W. Schwartz;Randy J. Seeley;Matthias H. Tschöp;Stephen C. Woods

  • Neuronal GLP1R mediates liraglutide’s anorectic but not glucose-lowering effect

    Stephanie Sisley;Ruth Gutierrez-Aguilar;Michael Scott;David A. D’Alessio

Frequent Co-Authors

Randy J. Seeley
Randy J. Seeley University of Michigan–Ann Arbor
Stephen C. Woods
Stephen C. Woods University of Cincinnati
Patrick Tso
Patrick Tso University of Cincinnati
Matthias H. Tschöp
Matthias H. Tschöp Technical University of Munich
Steven E. Kahn
Steven E. Kahn University of Washington
Stephen C. Benoit
Stephen C. Benoit University of Cincinnati
James P. Herman
James P. Herman University of Cincinnati
Julio Rosenstock
Julio Rosenstock The University of Texas Southwestern Medical Center
Amalia Gastaldelli
Amalia Gastaldelli National Research Council (CNR)
Luc Tappy
Luc Tappy University of Lausanne

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring medicine as a career can open doors to a range of vital roles in healthcare. Aside from the traditional MD pathway, many students are choosing flexible online degrees to enter other rewarding fields. Specialized programs help prepare for in-demand careers, often at a fraction of the cost and time required for a full medical degree.

For those interested in healthcare data and administration, rhia certification programs online can lead to certification for information management roles. Medical billing and coding experts are also essential in every clinical setting, and you can qualify through a low cost medical coding and billing online program.

Nursing remains an accessible and fulfilling pathway, with several affordable np programs available for those aiming to become nurse practitioners. If you’re just starting out, consider enrolling in an online nursing school to begin your journey in patient care.

These online options enable you to balance studies with work and life commitments while progressing toward a meaningful healthcare career.

Best Scientists Citing David A. D'Alessio

Trending Scientists