World's Best Scientists 2026 revealed!

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Medicine

D-Index
126
Citations
79067
World Ranking
2890
National Ranking
152

Research.com Recognitions

  • 2016 - Member of Academia Europaea
  • 2013 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Agricultural and Nutritional Sciences
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Matthias H. Tschöp is affiliated with the Technical University of Munich in Germany. Their research primarily focuses on Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Key subfields of study include Molecular Biology, Physiology, Endocrinology, Diabetes and Metabolism, Endocrine and Autonomic Systems, and Surgery.

Their work covers several main topics, such as Diabetes Treatment and Management, Adipose Tissue and Metabolism, Regulation of Appetite and Obesity, Pancreatic Function and Diabetes, Receptor Mechanisms and Signaling, Pharmacology and Obesity Treatment, and Diet and Metabolism Studies.

Frequent co-authors in Matthias H. Tschöp's research include:

  • Timo D. Müller
  • Richard D. DiMarchi
  • Brian Finan
  • Cristina García-Cáceres
  • Susanna M. Hofmann

The scientist has contributed multiple papers to notable publication venues with a concentration in metabolic and cellular biology fields. These frequent venues include:

  • Nature Metabolism
  • Cell Metabolism
  • Molecular Metabolism
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications

Selected recent research papers authored or co-authored by Matthias H. Tschöp include:

  • "Anti-obesity drug discovery: advances and challenges," 2021, Nature Reviews Drug Discovery
  • "Definition and diagnostic criteria of clinical obesity," 2025, The Lancet Diabetes & Endocrinology
  • "The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling," 2021, Cell Metabolism
  • "POMC neuronal heterogeneity in energy balance and beyond: an integrated view," 2021, Nature Metabolism
  • "Targeted pharmacological therapy restores β-cell function for diabetes remission," 2020, Nature Metabolism

Their contributions have been recognized by memberships and awards, including:

  • Member of Academia Europaea (2016)
  • Member of the German National Academy of Sciences Leopoldina with a focus on Agricultural and Nutritional Sciences (2013)
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Ghrelin induces adiposity in rodents.

    Matthias Tschöp;David L. Smiley;Mark L. Heiman

  • Circulating Ghrelin Levels Are Decreased in Human Obesity

    Matthias Tschöp;Christian Weyer;P. Antonio Tataranni;Viswanath Devanarayan

  • The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

    Michael A Cowley;Roy G Smith;Sabrina Diano;Matthias Tschöp

  • Obesity is associated with hypothalamic injury in rodents and humans

    Joshua P. Thaler;Chun Xia Yi;Ellen A. Schur;Stephan J. Guyenet

  • Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin.

    Aart J van der Lely;Matthias Tschöp;Mark L Heiman;Ezio Ghigo

  • GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for a crucial mediating role of hypothalamic agouti-related protein.

    Matthias Tschöp;Michael A Statnick;Todd M Suter;Mark L Heiman

  • Glucagon-like peptide 1 (GLP-1)

    T.D. Müller;B. Finan;S.R. Bloom;D. D'Alessio

  • The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis

    Daniela Cota;Giovanni Marsicano;Matthias Tschöp;Yvonne Grübler

  • Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa

    B Otto;U Cuntz;E Fruehauf;R Wawarta

  • Extent and Direction of Ghrelin Transport Across the Blood-Brain Barrier Is Determined by Its Unique Primary Structure

    William A. Banks;Matthias Tschöp;Sandra M. Robinson;Mark L. Heiman

  • Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite

    Alfonso Abizaid;Zhong-Wu Liu;Zane Bruce Andrews;Marya Shanabrough

  • Minireview: Ghrelin and the regulation of energy balance - A hypothalamic perspective

    Tamas L. Horvath;Sabrina Diano;Peter Sotonyi;Mark Heiman

  • Sirt1 protects against high-fat diet-induced metabolic damage

    Paul T. Pfluger;Daniel Herranz;Susana Velasco-Miguel;Manuel Serrano

  • Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women.

    Karen L Teff;Sharon S Elliott;Matthias Tschöp;Timothy J Kieffer

  • Ghrelin controls hippocampal spine synapse density and memory performance

    Sabrina Diano;Susan A Farr;Susan A Farr;Stephen C Benoit;Ewan C McNay

  • Post-prandial decrease of circulating human ghrelin levels.

    M. Tschöp;R. Wawarta;R. L. Riepl;S. Friedrich

  • Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity.

    Giampiero Muccioli;Matthias Tschöp;Mauro Papotti;Romano Deghenghi

  • A guide to analysis of mouse energy metabolism

    Matthias H Tschöp;John R Speakman;John R Speakman;Jonathan R S Arch;Johan Auwerx

  • UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

    Zane B. Andrews;Zhong-Wu Liu;Nicholas Walllingford;Derek M. Erion

  • Animal models of obesity and diabetes mellitus

    Maximilian Kleinert;Christoffer Clemmensen;Susanna M Hofmann;Mary C Moore

Frequent Co-Authors

Paul T. Pfluger
Paul T. Pfluger Helmholtz Zentrum München
Richard D. DiMarchi
Richard D. DiMarchi Indiana University
Chun-Xia Yi
Chun-Xia Yi University of Amsterdam
Rubén Nogueiras
Rubén Nogueiras University of Santiago de Compostela
Stephen C. Woods
Stephen C. Woods University of Cincinnati
Martin Jastroch
Martin Jastroch Stockholm University
Tamas L. Horvath
Tamas L. Horvath Yale University
Randy J. Seeley
Randy J. Seeley University of Michigan–Ann Arbor
Martin Bidlingmaier
Martin Bidlingmaier Ludwig-Maximilians-Universität München
David A. D'Alessio
David A. D'Alessio Duke University

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