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D-Index & Metrics

Medicine

D-Index
78
Citations
20144
World Ranking
18121
National Ranking
249

Overview

Miguel López is affiliated with the University of Santiago de Compostela in Spain and has an extensive publication record across various fields related to medicine and biology. Their research primarily covers medicine, biochemistry, genetics and molecular biology, and neuroscience, with a strong focus on physiology, endocrine and autonomic systems, molecular biology, epidemiology, and endocrinology, diabetes, and metabolism.

The scientist's main topics of work include adipose tissue and metabolism, regulation of appetite and obesity, adipokines, inflammation, and metabolic diseases, circadian rhythm and melatonin, diet and metabolism studies, metabolism in relation to diabetes and cancer, and pancreatic function and diabetes.

Miguel López has published repeatedly in several notable venues. Frequent publication journals include Nature Communications, Molecular Metabolism, Cell Metabolism, Metabolism, and Frontiers in Endocrinology.

Recent publications demonstrate a varied and significant contribution to metabolic and physiological research. Selected papers include:

  • Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis, 2022, Journal of Hepatology
  • Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty, 2020, Cell Metabolism
  • Multifaceted actions of melanin-concentrating hormone on mammalian energy homeostasis, 2021, Nature Reviews Endocrinology
  • Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation, 2021, Nature Metabolism
  • O-GlcNAcylated p53 in the liver modulates hepatic glucose production, 2021, Nature Communications

The scientist has collaborated frequently with several researchers, including Carlos Diéguez, Rubén Nogueiras, Ismael González-García, Edward Milbank, and Nathalia Romanelli Vicente Dragano.

Best Publications

  • Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

    Miguel González López;Miguel González López;Luis Varela;María J. Sánchez Vazquez;Sergio Rodriguez-Cuenca

  • AMPK: a metabolic gauge regulating whole-body energy homeostasis.

    Ricardo Lage;Carlos Diéguez;Antonio Vidal-Puig;Miguel López

  • BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

    Andrew J. Whittle;Stefania Carobbio;Luís Martins;Marc Slawik;Marc Slawik

  • GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and Browning Through Hypothalamic AMPK

    Daniel Beiroa;Monica Imbernon;Rosalía Gallego;Ana Senra

  • Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

    Miguel Lopez;Ricardo Lage;Asish K Saha;Diego Perez-Tilve

  • The cellular and molecular bases of leptin and ghrelin resistance in obesity.

    Huxing Cui;Huxing Cui;Miguel López;Kamal Rahmouni;Kamal Rahmouni

  • Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK

    Pablo Blanco Martinez De Morentin;Ismael Gonzalez-Garcia;Luis Martins;Ricardo Lage

  • Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.

    Christopher J Lelliott;Christopher J Lelliott;Gema Medina-Gomez;Natasa Petrovic;Adrienn Kis

  • Agouti-related peptide, neuropeptide Y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus.

    Luisa M. Seoane;Miguel López;Sulay Tovar;Felipe F. Casanueva

  • Hypothalamic AMPK: A canonical regulator of whole-body energy balance

    Miguel López;Rubén Nogueiras;Manuel Tena-Sempere;Carlos Diéguez

  • AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest

    Elena Doménech;Carolina Maestre;Lorena Esteban-Martínez;David Partida

  • Leptin regulation of prepro-orexin and orexin receptor mRNA levels in the hypothalamus.

    Miguel López;Luisa Seoane;María del Carmen García;Francisca Lago

  • The Mammalian Target of Rapamycin as Novel Central Regulator of Puberty Onset via Modulation of Hypothalamic Kiss1 System

    J Roa;D Garcia-Galiano;L Varela;M A Sánchez-Garrido

  • Energy balance regulation by thyroid hormones at central level

    Miguel López;Clara V. Alvarez;Rubén Nogueiras;Carlos Diéguez

  • Central Ceramide-Induced Hypothalamic Lipotoxicity and ER Stress Regulate Energy Balance

    Cristina Contreras;Ismael González-García;Noelia Martínez-Sánchez;Patricia Seoane-Collazo

  • Brain fatty acid synthase activates PPARα to maintain energy homeostasis

    Manu V. Chakravarthy;Yimin Zhu;Miguel López;Li Yin

  • Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance

    Noelia Martínez-Sánchez;Patricia Seoane-Collazo;Cristina Contreras;Luis Varela

  • Direct Control of Peripheral Lipid Deposition by CNS GLP-1 Receptor Signaling Is Mediated by the Sympathetic Nervous System and Blunted in Diet-Induced Obesity

    Ruben Nogueiras;Diego Pérez-Tilve;Christelle Veyrat-Durebex;Donald A. Morgan

  • Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase

    Pablo Blanco Martinez De Morentin;Andrew J Whittle;Johan Fernø;Rubén Nogueiras

  • Tamoxifen-Induced Anorexia Is Associated With Fatty Acid Synthase Inhibition in the Ventromedial Nucleus of the Hypothalamus and Accumulation of Malonyl-CoA

    Miguel López;Christopher J. Lelliott;Sulay Tovar;Wendy Kimber

Frequent Co-Authors

Carlos Dieguez
Carlos Dieguez University of Santiago de Compostela
Rubén Nogueiras
Rubén Nogueiras University of Santiago de Compostela
Manuel Tena-Sempere
Manuel Tena-Sempere University of Córdoba
Antonio Vidal-Puig
Antonio Vidal-Puig University of Cambridge
Kamal Rahmouni
Kamal Rahmouni University of Iowa Health Care
Juan Carlos Roa
Juan Carlos Roa University of Córdoba
José Manuel Fernández-Real
José Manuel Fernández-Real University of Girona
Leonor Pinilla
Leonor Pinilla University of Córdoba
Asish K. Saha
Asish K. Saha Boston University
Vidar M. Steen
Vidar M. Steen University of Bergen

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