World's Best Scientists 2026 revealed!
Manuel Tena-Sempere

Manuel Tena-Sempere

Award Badge
Medicine
Spain
2023

D-Index & Metrics

Medicine

D-Index
111
Citations
37520
World Ranking
5396
National Ranking
75

Research.com Recognitions

  • 2023 - Research.com Medicine in Spain Leader Award

Overview

Manuel Tena-Sempere is affiliated with the University of Córdoba in Spain and has contributed extensively to the field of Medicine, with a particular focus on Reproductive Medicine. Their research encompasses a range of subfields including Molecular Biology, Endocrine and Autonomic Systems, Physiology, and Endocrinology, Diabetes and Metabolism.

The scientist's work prominently addresses topics such as hypothalamic control of reproductive hormones, ovarian function and disorders, regulation of appetite and obesity, plant reproductive biology, adipose tissue and metabolism, reproductive biology and fertility, as well as birth, development, and health.

Notable recent papers authored or coauthored by Manuel Tena-Sempere include:

  • Metabolic dysfunction in polycystic ovary syndrome: Pathogenic role of androgen excess and potential therapeutic strategies (2020, Molecular Metabolism)
  • Interaction between gut microbiota and sex hormones and their relation to sexual dimorphism in metabolic diseases (2023, Biology of Sex Differences)
  • Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty (2020, Cell Metabolism)
  • GnRH replacement rescues cognition in Down syndrome (2022, Science)
  • Kisspeptins and the neuroendocrine control of reproduction: Recent progress and new frontiers in kisspeptin research (2022, Frontiers in Neuroendocrinology)

Frequent coauthors in their scientific collaborations include Francisco Ruíz-Pino, Francisco Gaytán, María J. Vázquez, Inmaculada Velasco, and Vincent Prévot.

The primary publication venues where Manuel Tena-Sempere's work appears repeatedly are:

  • Yearbook of pediatric endocrinology
  • Metabolism
  • Molecular Metabolism
  • Journal of the Endocrine Society
  • Endocrine Abstracts

Manuel Tena-Sempere's research contributions concentrate on elucidating complex physiological and molecular mechanisms involved in reproductive health and metabolic regulation. Their multidisciplinary approach integrates aspects of endocrinology and molecular biology to better understand reproductive disorders and metabolic diseases.

Best Publications

  • Developmental and Hormonally Regulated Messenger Ribonucleic Acid Expression of KiSS-1 and Its Putative Receptor, GPR54, in Rat Hypothalamus and Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide

    V M Navarro;J M Castellano;R Fernández-Fernández;M L Barreiro

  • Expert consensus document: European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment

    Ulrich Boehm;Pierre Marc Bouloux;Mehul T. Dattani;Nicolas De Roux

  • Kisspeptins and Reproduction: Physiological Roles and Regulatory Mechanisms

    Leonor Pinilla;Enrique Aguilar;Carlos Dieguez;Robert P. Millar

  • Intestinal Microbiota Is Influenced by Gender and Body Mass Index.

    Carmen Haro;Carmen Haro;Oriol A. Rangel-Zúñiga;Oriol A. Rangel-Zúñiga;Juan F. Alcalá-Díaz;Juan F. Alcalá-Díaz;Francisco Gómez-Delgado;Francisco Gómez-Delgado

  • Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition.

    J M Castellano;V M Navarro;R Fernández-Fernández;R Nogueiras

  • Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54

    V. M. Navarro;R. Fernández-Fernández;J. M. Castellano;J. Roa

  • Sexual differentiation of Kiss1 gene expression in the brain of the rat

    Alexander S. Kauffman;Michelle L. Gottsch;Juan Roa;Alisa C. Byquist

  • Characterization of the potent luteinizing hormone-releasing activity of KiSS-1 peptide, the natural ligand of GPR54.

    V M Navarro;J M Castellano;R Fernández-Fernández;S Tovar

  • Novel Expression and Functional Role of Ghrelin in Rat Testis

    M. Tena-Sempere;M. L. Barreiro;L. C. González;F. Gaytán

  • An International Consortium Update: Pathophysiology, Diagnosis, and Treatment of Polycystic Ovarian Syndrome in Adolescence.

    Lourdes Ibáñez;Sharon E Oberfield;Selma Witchel;Richard J Auchus

  • Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation

    Antonia K Roseweir;Alexander S Kauffman;Jeremy Troy Smith;Kathryn A Guerriero

  • Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK

    Pablo Blanco Martinez De Morentin;Ismael Gonzalez-Garcia;Luis Martins;Ricardo Lage

  • Novel signals for the integration of energy balance and reproduction.

    R. Fernandez-Fernandez;A.C. Martini;V.M. Navarro;J.M. Castellano

  • New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function.

    Juan Roa;Enrique Aguilar;Enrique Aguilar;Carlos Dieguez;Carlos Dieguez;Leonor Pinilla;Leonor Pinilla

  • Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat.

    V. M. Navarro;J. M. Castellano;R. Fernández-Fernández;S. Tovar

  • Metabolic dysfunction in polycystic ovary syndrome: Pathogenic role of androgen excess and potential therapeutic strategies.

    Miguel A. Sanchez-Garrido;Manuel Tena-Sempere

  • Correction: Corrigendum: Beyond the brain-Peripheral kisspeptin signaling is essential for promoting endometrial gland development and function

    Silvia León;Daniela Fernandois;Alexandra Sull;Judith Sull

  • Immunolocalization of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in the cyclic human ovary.

    Felice Gaytan;M Barreiro;Lisa Chopin;Adrian Herington

  • Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line.

    Raul M. Luque;Rhonda D. Kineman;Rhonda D. Kineman;Manuel Tena-Sempere;Manuel Tena-Sempere

  • Expression of Hypothalamic KiSS-1 System and Rescue of Defective Gonadotropic Responses by Kisspeptin in Streptozotocin-Induced Diabetic Male Rats

    Juan M. Castellano;Victor M. Navarro;Rafael Fernández-Fernández;Juan Roa

Frequent Co-Authors

Leonor Pinilla
Leonor Pinilla University of Córdoba
Carlos Dieguez
Carlos Dieguez University of Santiago de Compostela
Juan Carlos Roa
Juan Carlos Roa University of Córdoba
Miguel López
Miguel López University of Santiago de Compostela
Felipe F. Casanueva
Felipe F. Casanueva University of Santiago de Compostela
Rubén Nogueiras
Rubén Nogueiras University of Santiago de Compostela
Robert A. Steiner
Robert A. Steiner University of Washington
Robert P. Millar
Robert P. Millar University of Pretoria
Jens D. Mikkelsen
Jens D. Mikkelsen University of Copenhagen
Justo P. Castaño
Justo P. Castaño University of Córdoba

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a healthcare career in the USA doesn’t always require following the traditional MD route. There are numerous online degree options and accelerated pathways designed for those seeking flexibility or quicker entry into the medical workforce.

Aspiring nurses can consider lpn program options, which offer a streamlined route to becoming a licensed practical nurse and gaining essential hands-on experience. If your interests lean toward mental health, accelerated msn psychiatric np programs prepare you for specialized practice as a psychiatric nurse practitioner—often in less time than conventional degrees.

Beyond clinical roles, online programs in healthcare management present a compelling alternative. For those seeking affordability and versatility, the cheapest online health science degree can open doors to administrative and leadership positions in health-related fields. Advancing further, the cheapest mha programs online equip graduates with advanced skills in healthcare administration, ideal for those aiming to manage hospitals or healthcare systems.

These online degrees and pathways offer flexible, cost-effective alternatives for building a rewarding healthcare career in America.

Best Scientists Citing Manuel Tena-Sempere

Trending Scientists

Recently Published Articles