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Neuroscience

D-Index
45
Citations
8488
World Ranking
6894
National Ranking
2982

Overview

Adam D. Bachstetter is affiliated with the University of Kentucky in the United States. Their research primarily spans the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology, with a substantial focus on subfields such as Neurology, Molecular Biology, Physiology, Epidemiology, and Cognitive Neuroscience.

The scientist's work centers around key topics including:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Alzheimer's disease research and treatments
  • Traumatic Brain Injury Research
  • Sleep and Wakefulness Research
  • Tryptophan and brain disorders
  • S100 Proteins and Annexins

Recent papers authored or co-authored by Adam D. Bachstetter include:

  • "Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain," 2021, Neurobiology of Aging
  • "Adaptive immune cells shape obesity-associated type 2 diabetes mellitus and less prominent comorbidities," 2021, Nature Reviews Endocrinology
  • "Dysregulation of Systemic Immunity in Aging and Dementia," 2021, Frontiers in Cellular Neuroscience
  • "Effects of advanced age upon astrocyte-specific responses to acute traumatic brain injury in mice," 2020, Journal of Neuroinflammation
  • "Inflammatory Regulation of CNS Barriers After Traumatic Brain Injury: A Tale Directed by Interleukin-1," 2021, Frontiers in Immunology

Frequent co-authors associated with this scientist include:

  • Teresa Macheda
  • Peter T. Nelson
  • Kelly N. Roberts
  • Ryan K. Shahidehpour
  • Marilyn J. Duncan

Adam D. Bachstetter has published regularly in several venues. Notable among these are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Acta Neuropathologica Communications
  • Journal of Neuroinflammation
  • SLEEP
  • Journal of Visualized Experiments

Best Publications

  • Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models.

    Scott J Webster;Adam D Bachstetter;Peter T Nelson;Frederick A Schmitt

  • CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity.

    Justin T. Rogers;Josh M. Morganti;Adam D. Bachstetter;Charles E. Hudson

  • Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats

    Adam D. Bachstetter;Josh M. Morganti;Jennifer Jernberg;Andrea Schlunk

  • Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease

    Jennifer L. Furman;Diana M. Sama;John C. Gant;Tina L. Beckett

  • Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ).

    Adam D Bachstetter;Bin Xing;Lucia de Almeida;Edgardo R Dimayuga

  • Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms

    David A. Costa;Jennifer R. Cracchiolo;Adam D. Bachstetter;Tiffany F. Hughes

  • Disease-related microglia heterogeneity in the hippocampus of Alzheimer’s disease, dementia with Lewy bodies, and hippocampal sclerosis of aging

    Adam D Bachstetter;Linda J Van Eldik;Frederick A Schmitt;Janna H Neltner

  • CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease

    Mibel M Pabon;Adam D Bachstetter;Charles E Hudson;Carmelina Gemma;Carmelina Gemma

  • Influence of predator stress on the consolidation versus retrieval of long-term spatial memory and hippocampal spinogenesis.

    David M. Diamond;Adam M. Campbell;Collin R. Park;James C. Woodson

  • The role of microglia in adult hippocampal neurogenesis

    Carmelina Gemma;Adam D. Bachstetter

  • Oxidative Stress and the Aging Brain: From Theory to Prevention

    Carmelina Gemma;Jennifer Vila;Adam Bachstetter;Paula C. Bickford

  • The p38 MAP Kinase Family as Regulators of Proinflammatory Cytokine Production in Degenerative Diseases of the CNS.

    Adam D. Bachstetter;Linda J. Van Eldik

  • Developmental Exposure to Polychlorinated Biphenyls Interferes with Experience-Dependent Dendritic Plasticity and Ryanodine Receptor Expression in Weanling Rats

    Dongren Yang;Kyung Ho Kim;Andrew Phimister;Adam D. Bachstetter

  • Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

    Scott J Webster;Adam D Bachstetter;Linda J Van Eldik

  • Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction in a Mouse Model That Exhibits Age-Dependent Progression of Alzheimer's Disease-Related Pathology

    Adam D. Bachstetter;Christopher M. Norris;Pradoldej Sompol;Donna M. Wilcock

  • Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain

    Ryan K. Shahidehpour;Rebecca E. Higdon;Nicole G. Crawford;Janna H. Neltner

  • A Systematic Review of Closed Head Injury Models of Mild Traumatic Brain Injury in Mice and Rats

    Colleen N. Bodnar;Kelly N. Roberts;Emma K. Higgins;Adam D. Bachstetter

  • The p38α MAPK Regulates Microglial Responsiveness to Diffuse Traumatic Brain Injury

    Adam D. Bachstetter;Rachel K. Rowe;Machi Kaneko;Danielle Goulding

  • Targeting innate immunity for neurodegenerative disorders of the central nervous system.

    Katrin I. Andreasson;Adam D. Bachstetter;Marco Colonna;Florent Ginhoux

  • Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα.

    Bin Xing;Adam D Bachstetter;Linda J Van Eldik

  • Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain

    Adam D Bachstetter;Mibel M Pabon;Michael J Cole;Charles E Hudson

Frequent Co-Authors

Linda J. Van Eldik
Linda J. Van Eldik University of Kentucky
Paula C. Bickford
Paula C. Bickford University of South Florida
Jonathan Lifshitz
Jonathan Lifshitz University of Arizona
Bruce F. O'Hara
Bruce F. O'Hara University of Kentucky
Alison E. Willing
Alison E. Willing University of South Florida
Ottavio Arancio
Ottavio Arancio Columbia University
Katrin Andreasson
Katrin Andreasson Stanford University
Bruce T. Lamb
Bruce T. Lamb Indiana University
George M. Smith
George M. Smith Temple University
Debra K. Moser
Debra K. Moser University of Kentucky

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