D. Martin Watterson

Overview

Best Publications

• Epithelial myosin light chain kinase–dependent barrier dysfunction mediates T cell activation–induced diarrhea in vivo

  Daniel R. Clayburgh;Terrence A. Barrett;Yueming Tang;Jon B. Meddings

  449
  Citations

• Targeting protein kinases in central nervous system disorders

  Laura K. Chico;Linda J. Van Eldik;D. Martin Watterson

  363
  Citations

• A novel p38α MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model

  Lenka Munoz;Lenka Munoz;Hantamalala Ralay Ranaivo;Saktimayee M Roy;Wenhui Hu;Wenhui Hu

  310
  Citations

• Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ).

  Adam D Bachstetter;Bin Xing;Lucia de Almeida;Edgardo R Dimayuga

  299
  Citations

• Calcium-Binding Proteins and the Molecular Basis of Calcium Action

  Linda J. Van Eldik;Joseph G. Zendegui;Daniel R. Marshak;D. Martin Watterson

  267
  Citations

• Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

  Eric Lloyd;Kathleen Somera-Molina;Kathleen Somera-Molina;Linda J Van Eldik;D Martin Watterson

  243
  Citations

• Glia as a therapeutic target: selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration.

  Hantamalala Ralay Ranaivo;Jeffrey M. Craft;Wenhui Hu;Ling Guo

  214
  Citations

• Glia Proinflammatory Cytokine Upregulation as a Therapeutic Target for Neurodegenerative Diseases: Function‐Based and Target‐Based Discovery Approaches

  Linda J. Van Eldik;Wendy L. Thompson;Hantamalala Ralay Ranaivo;Heather A. Behanna

  191
  Citations

• Protein kinase involved in lung injury susceptibility: Evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment

  Mark S. Wainwright;Janet Rossi;James Schavocky;Susan Crawford

  190
  Citations

• Calmodulin and signal transduction

  Linda J. van Eldik;D. Martin Watterson

  188
  Citations

• Mechanism of glial activation by S100B: involvement of the transcription factor NFκB

  Amy G.M Lam;Tanuja Koppal;Keith T Akama;Ling Guo

  171
  Citations

• Glial activation links early-life seizures and long-term neurologic dysfunction : Evidence using a small molecule inhibitor of proinflammatory cytokine upregulation

  Kathleen C. Somera-Molina;Beverley Robin;Cherie Ann Somera;Christopher Anderson

  169
  Citations

• A kinase-related protein stabilizes unphosphorylated smooth muscle myosin minifilaments in the presence of ATP.

  V P Shirinsky;A V Vorotnikov;K G Birukov;A K Nanaev

  164
  Citations

• Spinach calmodulin: isolation, characterization, and comparison with vertebrate calmodulins.

  D. Martin Watterson;David B. Iverson;Linda J. Van Eldik

  160
  Citations

• Neuroinflammation: a potential therapeutic target.

  Jeffrey M Craft;D Martin Watterson;Linda J Van Eldik

  152
  Citations

• Human amyloid β-induced neuroinflammation is an early event in neurodegeneration

  Jeffrey M. Craft;D. Martin Watterson;Linda J. Van Eldik

  150
  Citations

• Structural characterization of a higher plant calmodulin : spinacia oleracea.

  Thomas J. Lukas;David B. Iverson;Michael Schleicher;D. Martin Watterson

  149
  Citations

• Affinity chromatography purification of a cyclic nucleotide phosphodiesterase using immobilized modulator protein, a troponin C-like protein from brain.

  D.Martin Watterson;Thomas C. Vanaman

  144
  Citations

• Aminopyridazines inhibit β-amyloid-induced glial activation and neuronal damage in vivo

  Jeffrey M. Craft;D.Martin Watterson;Sally A. Frautschy;Linda J.Van Eldik

  144
  Citations

• An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury.

  Anastasia V. Velentza;Mark S. Wainwright;Magdalena Zasadzki;Salida Mirzoeva

  140
  Citations