World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
124
Citations
52250
World Ranking
532
National Ranking
334

Medicine

D-Index
125
Citations
52974
World Ranking
3117
National Ranking
1721

Overview

Joe G.N. Garcia is affiliated with the University of Arizona in the United States. Their research spans multiple fields, focusing primarily on medicine and biochemistry, genetics, and molecular biology. The scientist has contributed extensively to pulmonary and respiratory medicine, molecular biology, epidemiology, cardiology and cardiovascular medicine, as well as physiology.

The main topics covered in their work include:

  • Pulmonary Hypertension Research and Treatments
  • Respiratory Support and Mechanisms
  • Sepsis Diagnosis and Treatment
  • Cardiovascular Function and Risk Factors
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Sarcoidosis and Beryllium Toxicity Research
  • Neonatal Respiratory Health Research

Some of the recent papers authored or coauthored by Joe G.N. Garcia are:

  • NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8, 2023, published in Science Advances
  • Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction, 2020, published in Redox Biology
  • Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension, 2021, published in American Journal of Physiology-Cell Physiology
  • Clinical Characteristics and Transplant-Free Survival Across the Spectrum of Pulmonary Vascular Disease, 2022, published in Journal of the American College of Cardiology
  • Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody, 2020, published in European Respiratory Journal

Joe G.N. Garcia has collaborated frequently with several coauthors, including:

  • Sara M. Camp
  • Nancy G. Casanova
  • Christian Bime
  • Saad Sammani
  • Franz Rischard

The scientist's work has appeared in various publication venues, with multiple contributions to:

  • Translational Research
  • Pulmonary Circulation
  • Redox Biology
  • The Journal of Heart and Lung Transplantation
  • American Journal of Physiology-Lung Cellular and Molecular Physiology

Best Publications

  • Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1

    Dominador J. Manalo;Ashley Rowan;Tera Lavoie;Lakshmi Natarajan

  • Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans

    Suraj Peri;Suraj Peri;J. Daniel Navarro;J. Daniel Navarro;Ramars Amanchy;Troels Z. Kristiansen;Troels Z. Kristiansen

  • Cytoskeletal regulation of pulmonary vascular permeability

    Steven M. Dudek;Joe G. N. Garcia

  • Multiple-laboratory comparison of microarray platforms

    Rafael A Irizarry;Daniel Warren;Forrest Spencer;Irene F Kim

  • Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

    Joe G.N. Garcia;Feng Liu;Alexander D. Verin;Anna Birukova

  • Regulation of endothelial cell gap formation and barrier dysfunction: Role of myosin light chain phosphorylation

    Joe G. N. Garcia;Harold W. Davis;Carolyn E. Patterson

  • Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study

    Imre Noth;Yingze Zhang;Shwu Fan Ma;Carlos Flores

  • Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury.

    Xinqi Peng;Paul M. Hassoun;Saad Sammani;Bryan J. McVerry

  • Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury.

    Shui Q. Ye;Brett A. Simon;James P. Maloney;April Zambelli-Weiner

  • Association Between the MUC5B Promoter Polymorphism and Survival in Patients With Idiopathic Pulmonary Fibrosis

    Anna L. Peljto;Yingze Zhang;Tasha E. Fingerlin;Shwu-Fan Ma

  • Activated Protein C Mediates Novel Lung Endothelial Barrier Enhancement ROLE OF SPHINGOSINE 1-PHOSPHATE RECEPTOR TRANSACTIVATION

    James H. Finigan;Steven M. Dudek;Patrick A. Singleton;Eddie T. Chiang

  • The role of the microtubules in tumor necrosis factor-α-induced endothelial cell permeability

    Irina Petrache;Anna Birukova;Sarah I. Ramirez;Joe G. N. Garcia

  • Mechanisms regulating endothelial cell barrier function

    Troy Stevens;Joe G. N. Garcia;D. Michael Shasby;Jahar Bhattacharya

  • Focal Adhesions: Paradigm for a Signaling Nexus

    Lewis H. Romer;Konstantin G. Birukov;Joe G.N. Garcia

  • Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1α-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer

    Stephen L. Archer;Mardi Gomberg-Maitland;Michael L. Maitland;Stuart Rich

  • Evans blue dye as a marker of albumin clearance in cultured endothelial monolayer and isolated lung.

    C. E. Patterson;R. A. Rhoades;J. G. N. Garcia

  • Thrombin-induced increase in albumin permeability across the endothelium.

    Joe G. N. Garcia;Joe G. N. Garcia;Joe G. N. Garcia;Alma Siflinger-Birnboim;Alma Siflinger-Birnboim;Alma Siflinger-Birnboim;Rena Bizios;Rena Bizios;Rena Bizios;Peter J. Del Vecchio;Peter J. Del Vecchio;Peter J. Del Vecchio

  • Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction.

    Anna A. Birukova;Ksenya Smurova;Ksenya Smurova;Konstantin G. Birukov;Kozo Kaibuchi

  • Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury

    Jeffrey R. Jacobson;Joseph W. Barnard;Dmitry N. Grigoryev;Shwu Fan Ma

  • Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase.

    Steven M. Dudek;Jeffrey R. Jacobson;Eddie T. Chiang;Konstantin G. Birukov

Frequent Co-Authors

Ting Wang
Ting Wang Washington University in St. Louis
Viswanathan Natarajan
Viswanathan Natarajan University of Illinois at Chicago
Alexander D. Verin
Alexander D. Verin Augusta University
Jason X.-J. Yuan
Jason X.-J. Yuan University of California, San Diego
Konstantin G. Birukov
Konstantin G. Birukov University of Chicago
Anna A. Birukova
Anna A. Birukova University of Maryland, Baltimore
Stephen M. Black
Stephen M. Black Florida International University
Yong Huang
Yong Huang Hong Kong University of Science and Technology
Denis English
Denis English Indiana University
Victor R. Gordeuk
Victor R. Gordeuk University of Illinois at Chicago

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