World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
134
Citations
59401
World Ranking
364
National Ranking
243

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Asrar B. Malik is affiliated with the University of Illinois at Chicago in the United States. Their research primarily spans the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology.

The scientist's work covers several subfields including Immunology, Molecular Biology, Pulmonary and Respiratory Medicine, Cell Biology, and Infectious Diseases. Their research topics are notably focused on Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Immune cells in cancer, Inflammasome and immune disorders, Neonatal Respiratory Health Research, COVID-19 Clinical Research Studies, Erythrocyte Function and Pathophysiology, and SARS-CoV-2 and COVID-19 Research.

Frequent co-authors in their publications include:

  • Jalees Rehman
  • Yoshikazu Tsukasaki
  • Zhigang Hong
  • Mark Maienschein-Cline
  • Lianghui Zhang

The scientist has published multiple papers in prominent journals and platforms. Notable recent papers include:

  • mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury (2020, Immunity)
  • Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation (2020, eLife)
  • IL-1β suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury (2020, Journal of Clinical Investigation)
  • The angiocrine Rspondin3 instructs interstitial macrophage transition via metabolic-epigenetic reprogramming and resolves inflammatory injury (2020, Nature Immunology)
  • Gasdermin D pores are dynamically regulated by local phosphoinositide circuitry (2022, Nature Communications)

Regarding publication venues, Asrar B. Malik has frequently contributed to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Immunity
  • iScience
  • Journal of Clinical Investigation

Asrar B. Malik was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 2015.

Best Publications

  • Reactive Oxygen Species in Inflammation and Tissue Injury

    Manish Mittal;Mohammad Rizwan Siddiqui;Khiem Tran;Sekhar P. Reddy

  • Signaling Mechanisms Regulating Endothelial Permeability

    Dolly Mehta;Asrar B. Malik

  • NF-κB activation as a pathological mechanism of septic shock and inflammation

    Shu Fang Liu;Asrar B. Malik

  • Regulation of endothelial permeability via paracellular and transcellular transport pathways.

    Yulia Komarova;Asrar B. Malik

  • Regulation of endothelial junctional permeability.

    Emily Vandenbroucke;Dolly Mehta;Richard Minshall;Asrar B. Malik

  • Regulation of vascular endothelial barrier function

    Hazel Lum;A. B. Malik

  • Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

    Anna Rita Cantelmo;Lena Christin Conradi;Aleksandra Brajic;Jermaine Goveia

  • Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function.

    C Tiruppathi;A B Malik;P J Del Vecchio;C R Keese

  • Inhibition of NF-κB Activation by Pyrrolidine Dithiocarbamate Prevents In Vivo Expression of Proinflammatory Genes

    Shu Fang Liu;Xiaobing Ye;Asrar B. Malik

  • NADPH Oxidase-Dependent Signaling in Endothelial Cells: Role in Physiology and Pathophysiology

    Randall S. Frey;Masuko Ushio–Fukai;Asrar B. Malik

  • Impairment of Store-Operated Ca2+ Entry in TRPC4-/- Mice Interferes With Increase in Lung Microvascular Permeability

    Chinnaswamy Tiruppathi;Marc Freichel;Stephen M. Vogel;Biman C. Paria

  • Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability

    Yulia A. Komarova;Kevin Kruse;Dolly Mehta;Asrar B. Malik

  • Gp60 Activation Mediates Albumin Transcytosis in Endothelial Cells by Tyrosine Kinase-dependent Pathway

    Chinnaswamy Tiruppathi;Wei Song;Magnus Bergenfeldt;Phillip Sass

  • Lipopolysaccharide Stimulates Platelet Secretion and Potentiates Platelet Aggregation via TLR4/MyD88 and the cGMP-Dependent Protein Kinase Pathway

    Guoying Zhang;Jingyan Han;Emily J. Welch;Richard D. Ye

  • Caveolin regulation of endothelial function.

    Richard D. Minshall;William C. Sessa;Radu V. Stan;Richard G. W. Anderson

  • Role of Ca2+ signaling in the regulation of endothelial permeability.

    Chinnaswamy Tiruppathi;Richard D. Minshall;Biman C. Paria;Stephen M. Vogel

  • Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury

    Kwong Tai Cheng;Shiqin Xiong;Zhiming Ye;Zhiming Ye;Zhigang Hong

  • In vivo inhibition of nuclear factor-kappa B activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock.

    Shu Fang Liu;Xiaobing Ye;Asrar B. Malik

  • Mechanisms regulating endothelial cell barrier function

    Troy Stevens;Joe G. N. Garcia;D. Michael Shasby;Jahar Bhattacharya

  • Increased endothelial albumin permeability mediated by protein kinase C activation.

    Joseph J. Lynch;Thomas J. Ferro;Frank A. Blumenstock;Anne M. Brockenauer

Frequent Co-Authors

Stephen M. Vogel
Stephen M. Vogel University of Illinois at Chicago
Richard D. Minshall
Richard D. Minshall University of Illinois at Chicago
Chinnaswamy Tiruppathi
Chinnaswamy Tiruppathi University of Illinois at Chicago
Dolly Mehta
Dolly Mehta University of Illinois at Chicago
Jalees Rehman
Jalees Rehman University of Illinois at Chicago
Arshad Rahman
Arshad Rahman University of Rochester
Richard D. Ye
Richard D. Ye Chinese University of Hong Kong, Shenzhen
Philip S. Barie
Philip S. Barie Cornell University
Joe G.N. Garcia
Joe G.N. Garcia University of Arizona
John W. Christman
John W. Christman The Ohio State University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Asrar B. Malik

Trending Scientists