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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
11885
World Ranking
12043
National Ranking
5161

Overview

Chinnaswamy Tiruppathi is affiliated with the University of Illinois at Chicago in the United States. Their research spans topics in biochemistry, genetics and molecular biology, immunology and microbiology, and medicine, reflecting a multidisciplinary approach to studying cellular and molecular mechanisms with a focus on immune and inflammatory processes.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology
  • Medicine

Within these fields, notable subfields of study are:

  • Immunology
  • Molecular Biology
  • Cell Biology
  • Cancer Research
  • Pulmonary and Respiratory Medicine

The research concentrates on several core topics, including:

  • Immune Response and Inflammation
  • Hippo pathway signaling and YAP/TAZ
  • Immune cells in cancer
  • NF-κB Signaling Pathways
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Erythrocyte Function and Pathophysiology
  • Hemoglobin structure and function

Chinnaswamy Tiruppathi has contributed to publications in various scientific venues with multiple papers appearing in:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Biology of the Cell
  • Immunity
  • Antioxidants

Some recent papers authored or co-authored by Tiruppathi include:

  • "trans-Endothelial neutrophil migration activates bactericidal function via Piezo1 mechanosensing," 2023, Immunity
  • "Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions," 2023, Nature Communications
  • "Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs," 2022, Nature Communications
  • "EphB1 interaction with caveolin-1 in endothelial cells modulates caveolae biogenesis," 2020, Molecular Biology of the Cell
  • "Nrf2 Regulates Anti-Inflammatory A20 Deubiquitinase Induction by LPS in Macrophages in Contextual Manner," 2021, Antioxidants

Frequent collaborators in Tiruppathi's research include:

  • Asrar B. Malik
  • Jalees Rehman
  • Yoshikazu Tsukasaki
  • Viswanathan Natarajan
  • Mark Maienschein-Cline

Best Publications

  • Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function.

    C Tiruppathi;A B Malik;P J Del Vecchio;C R Keese

  • Impairment of Store-Operated Ca2+ Entry in TRPC4-/- Mice Interferes With Increase in Lung Microvascular Permeability

    Chinnaswamy Tiruppathi;Marc Freichel;Stephen M. Vogel;Biman C. Paria

  • Gp60 Activation Mediates Albumin Transcytosis in Endothelial Cells by Tyrosine Kinase-dependent Pathway

    Chinnaswamy Tiruppathi;Wei Song;Magnus Bergenfeldt;Phillip Sass

  • Role of Ca2+ signaling in the regulation of endothelial permeability.

    Chinnaswamy Tiruppathi;Richard D. Minshall;Biman C. Paria;Stephen M. Vogel

  • Size and Dynamics of Caveolae Studied Using Nanoparticles in Living Endothelial Cells

    Zhenjia Wang;Chinnaswamy Tiruppathi;Richard D. Minshall;Asrar B. Malik

  • Endothelial Cell-Surface Gp60 Activates Vesicle Formation and Trafficking via Gi-Coupled Src Kinase Signaling Pathway

    Richard D. Minshall;Chinnaswamy Tiruppathi;Stephen M. Vogel;Walter D. Niles

  • Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer.

    Theresa A. John;Stephen M. Vogel;Chinnaswamy Tiruppathi;Asrar B. Malik

  • Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: a mechanism for stabilizing neutrophil adhesion.

    Y Sugama;C Tiruppathi;K offakidevi;T T Andersen

  • Ca2+ Signaling, TRP Channels, and Endothelial Permeability

    Chinnaswamy Tiruppathi;Gias U. Ahmmed;Stephen M. Vogel;Asrar B. Malik

  • Ca2+ signalling and PKCα activate increased endothelial permeability by disassembly of VE—cadherin junctions

    Raudel Sandoval;Asrar B. Malik;Richard D. Minshall;Panos Kouklis

  • RhoA Interaction with Inositol 1,4,5-Trisphosphate Receptor and Transient Receptor Potential Channel-1 Regulates Ca2+ Entry ROLE IN SIGNALING INCREASED ENDOTHELIAL PERMEABILITY

    Dolly Mehta;Gias U. Ahmmed;Biman C. Paria;Michael Holinstat

  • Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells.

    Ayesha N. Shajahan;Barbara K. Timblin;Raudel Sandoval;Chinnaswamy Tiruppathi

  • Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function.

    Richard D. Minshall;Chinnaswamy Tiruppathi;Stephen M. Vogel;Asrar B. Malik

  • Isolation and characterization of a cell surface albumin-binding protein from vascular endothelial cells.

    Chinnaswamy Tiruppathi;Alison Finnegan;Asrar B. Malik

  • Endothelin-1 stimulates DNA synthesis and proliferation of pulmonary artery smooth muscle cells.

    K. Janakidevi;M. A. Fisher;P. J. Del Vecchio;C. Tiruppathi

  • Tumor necrosis factor-α-induced TRPC1 expression amplifies store-operated Ca2+ influx and endothelial permeability

    Biman C. Paria;Stephen M. Vogel;Gias U. Ahmmed;Setara Alamgir

  • Albumin uptake and transcytosis in endothelial cells in vivo induced by albumin-binding protein.

    Stephen M. Vogel;Richard D. Minshall;Milena Pilipović;Chinnaswamy Tiruppathi

  • Angiopoietin-1 Opposes VEGF-Induced Increase in Endothelial Permeability by Inhibiting TRPC1-Dependent Ca2+ Influx

    David Jho;Dolly Mehta;Gias Ahmmed;Xiao Pei Gao

  • Protein kinase Cα phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells.

    Gias U. Ahmmed;Dolly Mehta;Stephen Vogel;Michael Holinstat

  • Albumin mediates the transcytosis of myeloperoxidase by means of caveolae in endothelial cells

    Chinnaswamy Tiruppathi;Tabassum Naqvi;Yubin Wu;Stephen M. Vogel

Frequent Co-Authors

Asrar B. Malik
Asrar B. Malik University of Illinois at Chicago
Stephen M. Vogel
Stephen M. Vogel University of Illinois at Chicago
Richard D. Minshall
Richard D. Minshall University of Illinois at Chicago
Dolly Mehta
Dolly Mehta University of Illinois at Chicago
Jalees Rehman
Jalees Rehman University of Illinois at Chicago
Heidi E. Hamm
Heidi E. Hamm Vanderbilt University
Marc Freichel
Marc Freichel Heidelberg University
Veit Flockerzi
Veit Flockerzi Saarland University
John W. Christman
John W. Christman The Ohio State University
Richard D. Ye
Richard D. Ye Chinese University of Hong Kong, Shenzhen

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