D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 73 Citations 22,026 254 World Ranking 2887 National Ranking 1056
Biology and Biochemistry D-index 80 Citations 25,911 290 World Ranking 2532 National Ranking 1365

Research.com Recognitions

Awards & Achievements

2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Biochemistry

Heidi E. Hamm mostly deals with G protein, Heterotrimeric G protein, Biochemistry, Receptor and Cell biology. In most of her G protein studies, her work intersects topics such as Biophysics. Heidi E. Hamm interconnects Protein structure, GTPase, G protein-coupled receptor and G alpha subunit in the investigation of issues within Heterotrimeric G protein.

Her Receptor research is multidisciplinary, relying on both Guanosine triphosphate, Binding site and Effector. Her Cell biology research is multidisciplinary, incorporating elements of Exocytosis and Cell membrane. Her GTP-Binding Protein gamma Subunits research focuses on GTP-Binding Protein beta Subunits and how it relates to Beta-propeller.

Her most cited work include:

  • The 2.0 Å crystal structure of a heterotrimeric G protein (1007 citations)
  • The many faces of G protein signaling. (1004 citations)
  • Heterotrimeric G protein activation by G-protein-coupled receptors (783 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are G protein, Cell biology, Biochemistry, Heterotrimeric G protein and Receptor. Particularly relevant to Transducin is her body of work in G protein. Her Transducin research incorporates themes from Phosphodiesterase and GTPase.

The various areas that Heidi E. Hamm examines in her Cell biology study include Exocytosis and Platelet, Thrombin. Her research investigates the connection with Biochemistry and areas like Biophysics which intersect with concerns in Nucleotide and Allosteric regulation. Her research on Heterotrimeric G protein frequently links to adjacent areas such as Effector.

She most often published in these fields:

  • G protein (43.90%)
  • Cell biology (41.46%)
  • Biochemistry (37.98%)

What were the highlights of her more recent work (between 2012-2020)?

  • Receptor (25.78%)
  • Cell biology (41.46%)
  • G protein (43.90%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Receptor, Cell biology, G protein, G protein-coupled receptor and Biochemistry. Her work carried out in the field of Receptor brings together such families of science as Platelet activation, Platelet, Exocytosis and Effector. The concepts of her Cell biology study are interwoven with issues in SNARE complex, Thrombin and Synaptotagmin 1.

She has included themes like Biophysics and Allosteric regulation in her G protein study. Her research in Biophysics intersects with topics in Protein structure, Rhodopsin, GTP' and Binding site. Her work focuses on many connections between Biochemistry and other disciplines, such as PROTEASE-ACTIVATED RECEPTOR 4, that overlap with her field of interest in Stereochemistry and Potency.

Between 2012 and 2020, her most popular works were:

  • Conformational Flexibility and Structural Dynamics in GPCR-Mediated G Protein Activation: A Perspective (70 citations)
  • Energetic analysis of the rhodopsin–G-protein complex links the α5 helix to GDP release (57 citations)
  • Protease-activated receptor (PAR) 1 and PAR4 differentially regulate factor V expression from human platelets. (48 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

Cell biology, G protein, Receptor, G protein-coupled receptor and Biochemistry are her primary areas of study. Her Cell biology study incorporates themes from Exocytosis, SNARE complex and Synaptotagmin 1. Her research integrates issues of Helix and Allosteric regulation in her study of G protein.

The Receptor study combines topics in areas such as Platelet activation and Pharmacology. As part of her studies on Biochemistry, Heidi E. Hamm frequently links adjacent subjects like Biophysics. Her studies in Heterotrimeric G protein integrate themes in fields like Neurotransmitter, Voltage-dependent calcium channel, Ternary complex, Presynaptic active zone and GTP'.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The many faces of G protein signaling.

Heidi E. Hamm.
Journal of Biological Chemistry (1998)

1669 Citations

The 2.0 Å crystal structure of a heterotrimeric G protein

David G. Lambright;John Sondek;Andrew Bohm;Nikolai P. Skiba.
Nature (1996)

1517 Citations

Heterotrimeric G protein activation by G-protein-coupled receptors

William M. Oldham;Heidi E. Hamm.
Nature Reviews Molecular Cell Biology (2008)

1357 Citations

The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S.

Joseph P. Noel;Heidi E. Hamm;Heidi E. Hamm;Paul B. Sigler.
Nature (1993)

1115 Citations

Crystal structure of a G-protein beta gamma dimer at 2.1A resolution

John Sondek;Andrew Bohm;David G. Lambright;David G. Lambright;Heidi E. Hamm.
Nature (1996)

1080 Citations

The 2.2 Å crystal structure of transducin-α complexed with GTP γ S

Joseph P. Noel;Heidi E. Hamm;Heidi E. Hamm;Paul B. Sigler.
Nature (1993)

1017 Citations

Insights into G protein structure, function, and regulation

Theresa M. Cabrera-Vera;Jurgen Vanhauwe;Tarita O. Thomas;Martina Medkova.
Endocrine Reviews (2003)

875 Citations

Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.

David G. Lambright;Joseph P. Noel;Joseph P. Noel;Heidi E. Hamm;Paul B. Sigler.
Nature (1994)

843 Citations

GTPase Mechanism of Gproteins From the 1.7-A Crystal Structure of Transducin alpha-GDP-AIF-4

John Sondek;David G. Lambright;Joseph P. Noel;Heidi E. Hamm;Heidi E. Hamm.
Nature (1994)

805 Citations

D2 Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+ Currents and Excitability via a Novel PLCβ1–IP3–Calcineurin-Signaling Cascade

Salvador Hernández-López;Tatiana Tkatch;Enrique Perez-Garci;Elvira Galarraga.
The Journal of Neuroscience (2000)

605 Citations

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