Klaus Peter Hofmann

Research.com Recognitions

• 1963 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1963 - Member of the National Academy of Sciences

Overview

Best Publications

• Crystal structure of opsin in its G-protein-interacting conformation

  Patrick Scheerer;Jung Hee Park;Peter W Hildebrand;Yong Ju Kim

  1308
  Citations

• Crystal structure of the ligand-free G-protein-coupled receptor opsin

  Jung Hee Park;Patrick Scheerer;Klaus Peter Hofmann;Klaus Peter Hofmann;Hui Woog Choe;Hui Woog Choe

  1121
  Citations

• Crystal structure of metarhodopsin II.

  Hui Woog Choe;Yong Ju Kim;Jung Hee Park;Takefumi Morizumi;Takefumi Morizumi

  783
  Citations

• Activation of rhodopsin: new insights from structural and biochemical studies

  Tetsuji Okada;Oliver P. Ernst;Krzysztof Palczewski;Klaus Peter Hofmann

  536
  Citations

• A G protein-coupled receptor at work: the rhodopsin model

  Klaus Peter Hofmann;Klaus Peter Hofmann;Patrick Scheerer;Peter W. Hildebrand;Hui-Woog Choe

  504
  Citations

• Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

  Olaf Fritze;Sławomir Filipek;Vladimir Kuksa;Krzysztof Palczewski

  426
  Citations

• Micropatterned immobilization of a G protein-coupled receptor and direct detection of G protein activation.

  Christoph Bieri;Oliver P. Ernst;Stephan Heyse;Klaus Peter Hofmann

  355
  Citations

• Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit.

  Oliver P. Ernst;Verena Gramse;Michael Kolbe;Klaus Peter Hofmann

  295
  Citations

• Kinetics, binding constant, and activation energy of the 48-kDa protein-rhodopsin complex by extra-metarhodopsin II.

  Andreas Schleicher;Hermann Kuehn;Klaus Peter Hofmann

  269
  Citations

• Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransduction.

  K Palczewski;S Jäger;J Buczyłko;R K Crouch

  249
  Citations

• Maximal rate and nucleotide dependence of rhodopsin-catalyzed transducin activation: initial rate analysis based on a double displacement mechanism.

  Martin Heck;Klaus Peter Hofmann

  240
  Citations

• Mutation of the Fourth Cytoplasmic Loop of Rhodopsin Affects Binding of Transducin and Peptides Derived from the Carboxyl-terminal Sequences of Transducin α and γ Subunits

  Oliver P. Ernst;Christoph K. Meyer;Ethan P. Marin;Peter Henklein

  238
  Citations

• Two different forms of metarhodopsin II : Schiff base deprotonation precedes proton uptake and signaling state

  Sophia Arnis;Klaus Peter Hofmann

  204
  Citations

• Crystal structure of pre-activated arrestin p44

  Yong Ju Kim;Klaus Peter Hofmann;Klaus Peter Hofmann;Oliver P. Ernst;Patrick Scheerer

  192
  Citations

• Crystal structure of a common GPCR-binding interface for G protein and arrestin

  Michal Szczepek;Florent Beyrière;Klaus-Peter Hofmann;Klaus-Peter Hofmann;Matthias Elgeti;Matthias Elgeti

  189
  Citations

• Sequence of late molecular events in the activation of rhodopsin.

  Bernhard Knierim;Klaus Peter Hofmann;Oliver P. Ernst;Wayne L. Hubbell

  183
  Citations

• Interaction of rhodopsin with the G-protein, transducin.

  Paul A. Hargrave;Heidi E. Hamm;K. P. Hofmann

  181
  Citations

• Phosphorylated rhodopsin and heparin induce similar conformational changes in arrestin.

  Krzysztof Palczewski;Alexander Pulvermüller;Janina Buczyłko;Klaus Peter Hofmann

  171
  Citations

• Interaction between photoactivated rhodopsin and its kinase: stability and kinetics of complex formation.

  Pulvermüller A;Palczewski K;Hofmann Kp

  169
  Citations

• Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors

  Heinz G. Körschen;Michael Beyermann;Frank Müller;Martin Heck

  161
  Citations