2026 Brian K. Kobilka: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	156	141	121	102	88	496	96968

Research.com Recognitions

2026 - Research.com Biology and Biochemistry in United States Leader Award
2025 - Research.com Biology and Biochemistry in United States Leader Award
2019 - Distinguished Scientist Award, American Heart Association
2015 - Fellow of the American Academy of Arts and Sciences
2015 - Fellow, National Academy of Inventors
2014 - Member of the National Academy of Medicine (NAM)
2013 - Member of the Royal Irish Academy
2012 - Nobel Prize for studies of G-protein-coupled receptors
2011 - Member of the National Academy of Sciences

Overview

Brian K. Kobilka is affiliated with Stanford University in the United States. Their research primarily falls within the fields of Biochemistry, Genetics and Molecular Biology, with a concentration on Molecular Biology, Cellular and Molecular Neuroscience, and Spectroscopy. Their work also touches on Pharmacology and Endocrinology, Diabetes and Metabolism.

The scientist's research focuses on several key topics including:

Receptor Mechanisms and Signaling
Neuropeptides and Animal Physiology
Mass Spectrometry Techniques and Applications
Lipid Membrane Structure and Behavior
Protein Structure and Dynamics
Pharmacological Receptor Mechanisms and Effects
Neuroscience and Neuropharmacology Research

They have contributed extensively to scientific literature, with frequent publications appearing in venues such as:

bioRxiv (Cold Spring Harbor Laboratory)
Nature
Nature Communications
Cell
Proceedings of the National Academy of Sciences

Some recent papers include:

Structure of the neurotensin receptor 1 in complex with β-arrestin 1, 2020, Nature
How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling, 2020, Cell
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist, 2020, Proceedings of the National Academy of Sciences
Structural insights into differences in G protein activation by family A and family B GPCRs, 2020, Science
G-protein activation by a metabotropic glutamate receptor, 2021, Nature

The scientist has worked frequently with collaborators including Haoqing Wang, Georgios Skiniotis, Kaavya Krishna Kumar, Peter Gmeiner, and Evan S. O'Brien.

Throughout their career, Brian K. Kobilka has received multiple honors such as:

Distinguished Scientist Award, American Heart Association, 2019
Fellow of the American Academy of Arts and Sciences, 2015
Fellow, National Academy of Inventors, 2015
Member of the National Academy of Medicine (NAM), 2014
Member of the Royal Irish Academy, 2013
Nobel Prize for studies of G-protein-coupled receptors, 2012
Member of the National Academy of Sciences, 2011

Best Publications

High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein–Coupled Receptor

Vadim Cherezov;Daniel M. Rosenbaum;Michael A. Hanson;Søren G. F. Rasmussen

4128
Citations
Crystal structure of the β2 adrenergic receptor-Gs protein complex.

Søren G. F. Rasmussen;Brian T. DeVree;Yaozhong Zou;Andrew C. Kruse

3614
Citations
The structure and function of G-protein-coupled receptors

Daniel M. Rosenbaum;Søren G. F. Rasmussen;Brian K. Kobilka

2846
Citations
Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.

Søren G F Rasmussen;Hee Jung Choi;Daniel M. Rosenbaum;Tong Sun Kobilka

2844
Citations
Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Søren G F Rasmussen;Hee Jung Choi;Juan Jose Fung;Els Pardon

2050
Citations
GPCR Engineering Yields High-Resolution Structural Insights into β2-Adrenergic Receptor Function

Daniel M. Rosenbaum;Vadim Cherezov;Michael A. Hanson;Søren G. F. Rasmussen

1746
Citations
Cloning of the gene and cDNA for mammalian β -adrenergic receptor and homology with rhodopsin

Richard A. F. Dixon;Brian K. Kobilka;David J. Strader;Jeffrey L. Benovic

1699
Citations
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Aashish Manglik;Andrew C. Kruse;Tong Sun Kobilka;Foon Sun Thian

1616
Citations
Functional Selectivity and Classical Concepts of Quantitative Pharmacology

Jonathan D. Urban;William P. Clarke;Mark Von Zastrow;David E. Nichols

1317
Citations
The Molecular Basis of G Protein-Coupled Receptor Activation.

William I. Weis;Brian K. Kobilka

1082
Citations
Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity

Brian K. Kobilka;Tong Sun Kobilka;Kiefer Daniel;John W. Regan

1059
Citations
Activation and allosteric modulation of a muscarinic acetylcholine receptor

Andrew C. Kruse;Aaron M. Ring;Aashish Manglik;Jianxin Hu

1015
Citations
Structure-based discovery of opioid analgesics with reduced side effects

Aashish Manglik;Henry Lin;Dipendra K. Aryal;John D. McCorvy

1014
Citations
Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor

B. K. Kobilka;H. Matsui;T. S. Kobilka;T. L. Yang-Feng

986
Citations
Structural insights into µ-opioid receptor activation

Weijiao Huang;Aashish Manglik;A. J. Venkatakrishnan;Toon Laeremans

972
Citations
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

Brian K. Kobilka;Richard A. F. Dixon;Thomas Frielle;Henrik G. Dohlman

967
Citations
βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance

Eric S. Bachman;Harveen Dhillon;Chen Yu Zhang;Saverio Cinti

954
Citations
Structure and function of an irreversible agonist-β2 adrenoceptor complex

Daniel M. Rosenbaum;Cheng Zhang;Joseph A. Lyons;Joseph A. Lyons;Ralph Holl

913
Citations
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.

Kazuko Haga;Andrew C. Kruse;Hidetsugu Asada;Takami Yurugi-Kobayashi

909
Citations
Structure and dynamics of the M3 muscarinic acetylcholine receptor

Andrew C. Kruse;Jianxin Hu;Albert C. Pan;Daniel H. Arlow

908
Citations

Frequent Co-Authors

William I. Weis Stanford University

Robert J. Lefkowitz Duke University

Jan Steyaert Vrije Universiteit Brussel

Andrew C. Kruse Harvard University

Roger K. Sunahara University of California, San Diego

Els Pardon Vrije Universiteit Brussel

Georgios Skiniotis Stanford University

Ulrik Gether University of Copenhagen

Marc G. Caron Duke University

Peter Gmeiner University of Erlangen-Nuremberg

External Links

Wikipedia of Brian K. Kobilka Personal website of Brian K. Kobilka

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