World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
64633
World Ranking
986
National Ranking
603

Research.com Recognitions

  • 2019 - Member of the National Academy of Sciences

Overview

William I. Weis was affiliated with Stanford University in the United States. Their research primarily focused on the intersection of Biochemistry, Genetics, and Molecular Biology, with a significant concentration on Molecular Biology.

Their scientific contributions encompassed several subfields, including Molecular Biology, Cell Biology, Atomic and Molecular Physics and Optics, Structural Biology, and Cellular and Molecular Neuroscience.

The main topics addressed in their work included:

  • Cellular Mechanics and Interactions
  • Force Microscopy Techniques and Applications
  • Wnt/β-catenin signaling in development and cancer
  • Cancer-related gene regulation
  • Heat shock proteins research
  • RNA Research and Splicing
  • Advanced Electron Microscopy Techniques and Applications

William I. Weis published frequently in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Journal of Biological Chemistry
  • Science Signaling
  • Biophysical Journal

They collaborated extensively with several co-authors, including:

  • Alexander R. Dunn
  • Sabine Pokutta
  • Jacob P. Mahoney
  • Elise S. Bruguera
  • Nicolas A. Bax

Among significant recent publications, notable papers include:

  • "Structural analysis of carbohydrate binding by the macrophage mannose receptor CD206" (2021) in the Journal of Biological Chemistry
  • "Structural basis of αE-catenin-F-actin catch bond behavior" (2020) in eLife
  • "The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin" (2022) in Proceedings of the National Academy of Sciences
  • "Limited dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction" (2020) in eLife
  • "Mechanism of the cadherin-catenin F-actin catch bond interaction" (2022) in eLife

In recognition of their scientific contributions, William I. Weis was elected as a Member of the National Academy of Sciences in 2019.

Best Publications

  • High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein–Coupled Receptor

    Vadim Cherezov;Daniel M. Rosenbaum;Michael A. Hanson;Søren G. F. Rasmussen

  • Crystal structure of the β2 adrenergic receptor-Gs protein complex.

    Søren G. F. Rasmussen;Brian T. DeVree;Yaozhong Zou;Andrew C. Kruse

  • Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.

    Søren G F Rasmussen;Hee Jung Choi;Daniel M. Rosenbaum;Tong Sun Kobilka

  • Structure of a nanobody-stabilized active state of the β2 adrenoceptor

    Søren G F Rasmussen;Hee Jung Choi;Juan Jose Fung;Els Pardon

  • GPCR Engineering Yields High-Resolution Structural Insights into β2-Adrenergic Receptor Function

    Daniel M. Rosenbaum;Vadim Cherezov;Michael A. Hanson;Søren G. F. Rasmussen

  • Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

    Aashish Manglik;Andrew C. Kruse;Tong Sun Kobilka;Foon Sun Thian

  • Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid

    W. Weis;J. H. Brown;S. Cusack;S. Cusack;J. C. Paulson

  • STRUCTURAL BASIS OF LECTIN-CARBOHYDRATE RECOGNITION

    William I. Weis;Kurt Drickamer

  • The C‐type lectin superfamily in the immune system

    William I. Weis;Maureen E. Taylor;Kurt Drickamer

  • Deconstructing the Cadherin-Catenin-Actin Complex

    Soichiro Yamada;Sabine Pokutta;Frauke Drees;William I. Weis

  • α-Catenin Is a Molecular Switch that Binds E-Cadherin-β-Catenin and Regulates Actin-Filament Assembly

    Frauke Drees;Sabine Pokutta;Soichiro Yamada;W. James Nelson

  • Structure of a C-type mannose-binding protein complexed with an oligosaccharide.

    William I. Weis;Kurt Drickamer;Wayne A. Hendrickson;Wayne A. Hendrickson

  • The Molecular Basis of G Protein-Coupled Receptor Activation.

    William I. Weis;Brian K. Kobilka

  • The β-Catenin Destruction Complex

    Jennifer L. Stamos;William I. Weis

  • Activation and allosteric modulation of a muscarinic acetylcholine receptor

    Andrew C. Kruse;Aaron M. Ring;Aashish Manglik;Jianxin Hu

  • The Structure of the β-Catenin/E-Cadherin Complex and the Molecular Basis of Diverse Ligand Recognition by β-Catenin

    Andrew H. Huber;William I. Weis

  • THREE-DIMENSIONAL STRUCTURE OF THE ARMADILLO REPEAT REGION OF BETA -CATENIN

    A H Huber;W J Nelson;W I Weis

  • Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex.

    Kira M. S. Misura;Richard H. Scheller;William I. Weis

  • Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.

    Kazuko Haga;Andrew C. Kruse;Hidetsugu Asada;Takami Yurugi-Kobayashi

  • Structure and dynamics of the M3 muscarinic acetylcholine receptor

    Andrew C. Kruse;Jianxin Hu;Albert C. Pan;Daniel H. Arlow

Frequent Co-Authors

Brian K. Kobilka
Brian K. Kobilka Stanford University
Axel T. Brunger
Axel T. Brunger Stanford University
W. James Nelson
W. James Nelson Stanford University
Kurt Drickamer
Kurt Drickamer Imperial College London
Maureen E. Taylor
Maureen E. Taylor Imperial College London
Andrew C. Kruse
Andrew C. Kruse Harvard University
Jan Steyaert
Jan Steyaert Vrije Universiteit Brussel
Georgios Skiniotis
Georgios Skiniotis Stanford University
Els Pardon
Els Pardon Vrije Universiteit Brussel
Beth L. Pruitt
Beth L. Pruitt University of California, Santa Barbara

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