D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 71 Citations 19,800 205 World Ranking 1442 National Ranking 19

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Receptor, Biochemistry, Cell biology, Nuclear receptor and Protein structure are his primary areas of study. H. Eric Xu has researched Receptor in several fields, including Small molecule and Binding site. He focuses mostly in the field of Biochemistry, narrowing it down to matters related to Biophysics and, in some cases, Peptide sequence.

In the subject of general Cell biology, his work in Signal transduction and Arrestin is often linked to Rhodopsin, thereby combining diverse domains of study. The Nuclear receptor study combines topics in areas such as Coactivator, CYP27A1 and Cytochrome P450. His Protein structure research is multidisciplinary, incorporating elements of Plasma protein binding and Cellular differentiation.

His most cited work include:

  • Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors (990 citations)
  • A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport (988 citations)
  • Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition (639 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Receptor, Biochemistry, Cell biology, G protein-coupled receptor and Signal transduction. His Receptor research integrates issues from Nuclear receptor and Drug discovery. His study in Nuclear receptor is interdisciplinary in nature, drawing from both Coactivator and Peroxisome proliferator-activated receptor.

His study in Biochemistry concentrates on Binding site, Abscisic acid, Protein structure, Phosphatase and Kinase. His research investigates the connection between Cell biology and topics such as Repressor that intersect with problems in Ubiquitin ligase. His Arrestin study in the realm of G protein-coupled receptor interacts with subjects such as Rhodopsin.

He most often published in these fields:

  • Receptor (53.27%)
  • Biochemistry (44.64%)
  • Cell biology (41.67%)

What were the highlights of his more recent work (between 2019-2021)?

  • G protein-coupled receptor (33.63%)
  • Receptor (53.27%)
  • Cell biology (41.67%)

In recent papers he was focusing on the following fields of study:

His main research concerns G protein-coupled receptor, Receptor, Cell biology, Ligand and Agonist. His G protein-coupled receptor study combines topics from a wide range of disciplines, such as Computational biology, Ion channel, G protein and Cell Surface Display Techniques. His Receptor research incorporates elements of Signal transduction, Central nervous system and Binding site.

H. Eric Xu interconnects Transmembrane domain, Inhibitory postsynaptic potential, Neurotransmission and Peptide in the investigation of issues within Cell biology. In his study, Fentanyl and Arrestin is inextricably linked to Neuroscience, which falls within the broad field of Agonist. A large part of his Biochemistry studies is devoted to Allosteric regulation.

Between 2019 and 2021, his most popular works were:

  • Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. (385 citations)
  • Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex (38 citations)
  • Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation. (35 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

The scientist’s investigation covers issues in G protein-coupled receptor, Receptor, G protein, Cell biology and Computational biology. The G protein-coupled receptor study combines topics in areas such as Agonist, Plasma protein binding and Neuroscience. The concepts of his Receptor study are interwoven with issues in Conserved sequence and Binding site.

As a member of one scientific family, H. Eric Xu mostly works in the field of Binding site, focusing on Ligand and, on occasion, Docking and Signal transduction. His G protein study combines topics in areas such as Arrestin, Structural biology, Fentanyl and Opioid. His Cell biology study combines topics from a wide range of disciplines, such as Methylation, Histone, Adenylate kinase, Linker DNA and Peptide.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

William R. Oliver;Jennifer L. Shenk;Mike R. Snaith;Caroline S. Russell.
Proceedings of the National Academy of Sciences of the United States of America (2001)

1379 Citations

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

H.Eric Xu;Millard H Lambert;Valerie G Montana;Derek J Parks.
Molecular Cell (2000)

1375 Citations

Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

Randy K. Bledsoe;Valerie G. Montana;Thomas B. Stanley;Chris J. Delves.
Cell (2002)

867 Citations

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα

H. Eric Xu;Thomas B. Stanley;Valerie G. Montana;Millard H. Lambert.
Nature (2002)

692 Citations

Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors

Robert T. Gampe;Valerie G. Montana;Millard H. Lambert;Aaron B. Miller.
Molecular Cell (2000)

682 Citations

Structural Features for Functional Selectivity at Serotonin Receptors

Daniel Wacker;Chong Wang;Vsevolod Katritch;Gye Won Han.
Science (2013)

607 Citations

A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors

Karsten Melcher;Ley-Moy Ng;Ley-Moy Ng;X. Edward Zhou;Fen-Fen Soon;Fen-Fen Soon.
Nature (2009)

585 Citations

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Yanyong Kang;X. Edward Zhou;Xiang Gao;Yuanzheng He.
Nature (2015)

552 Citations

DWARF 53 acts as a repressor of strigolactone signalling in rice

Liang Jiang;Xue Liu;Guosheng Xiong;Huihui Liu.
Nature (2013)

540 Citations

Peroxisome proliferator-activated receptors: from genes to physiology.

Steven A. Kliewer;H. Eric Xu;Millard H. Lambert;Timothy M. Willson.
Recent Progress in Hormone Research (2001)

522 Citations

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