Millard H. Lambert

Overview

Best Publications

• Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.

  R T Nolte;G B Wisely;S Westin;J E Cobb

  2443
  Citations

• Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha.

  Marcia L. Moss;S.-L. Catherine Jin;Marcos E. Milla;William Burkhart

  2091
  Citations

• A critical assessment of docking programs and scoring functions

  Gregory L. Warren;C. Webster Andrews;Anna-Maria Capelli;Brian Clarke

  1931
  Citations

• Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

  H.Eric Xu;Millard H Lambert;Valerie G Montana;Derek J Parks

  1464
  Citations

• A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

  William R. Oliver;Jennifer L. Shenk;Mike R. Snaith;Caroline S. Russell

  1432
  Citations

• The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

  Stacey A. Jones;Linda B. Moore;Jennifer L. Shenk;G. Bruce Wisely

  1221
  Citations

• Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

  Randy K. Bledsoe;Valerie G. Montana;Thomas B. Stanley;Chris J. Delves

  971
  Citations

• The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity

  R. E. Watkins;G. B. Wisely;L. B. Moore;J. L. Collins

  939
  Citations

• Peroxisome proliferator-activated receptor γ and metabolic disease

  Timothy M. Willson;Millard H. Lambert;Steven A. Kliewer

  787
  Citations

• Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα

  H. Eric Xu;Thomas B. Stanley;Valerie G. Montana;Millard H. Lambert

  754
  Citations

• Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors.

  Robert T. Gampe;Valerie G. Montana;Millard H. Lambert;Aaron B. Miller

  731
  Citations

• Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

  H.E. Xu;M.H. Lambert;V.G. Montana;K.D. Plunket

  672
  Citations

• Molecular determinants of nuclear receptor-corepressor interaction.

  Valentina Perissi;Lena M. Staszewski;Eileen M. McInerney;Riki Kurokawa

  615
  Citations

• Peroxisome proliferator-activated receptors: from genes to physiology.

  Steven A. Kliewer;H. Eric Xu;Millard H. Lambert;Timothy M. Willson

  546
  Citations

• Identification of a Novel Human Constitutive Androstane Receptor (CAR) Agonist and Its Use in the Identification of CAR Target Genes

  Jodi M. Maglich;Derek J. Parks;Linda B. Moore;Jon L. Collins

  511
  Citations

• Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules.

  Andreas Ludwig;Christian Hundhausen;Millard H. Lambert;Neil Broadway

  461
  Citations

• Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.

  Linda B. Moore;Jodi M. Maglich;David D. McKee;Bruce Wisely

  449
  Citations

• Atomic Structure of PDE4: Insights into Phosphodiesterase Mechanism and Specificity

  Robert X. Xu;Anne M. Hassell;Dana Vanderwall;Millard H. Lambert

  436
  Citations

• 2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin.

  Ryan E. Watkins;Jodi M. Maglich;Linda B. Moore;G. Bruce Wisely

  423
  Citations

• Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor.

  Brett Lovejoy;Anne Cleasby;Anne M. Hassell;Kelly Longley

  413
  Citations