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Yoshitaka Sekido

Yoshitaka Sekido

D-Index & Metrics

Medicine

D-Index
80
Citations
21736
World Ranking
17191
National Ranking
550

Overview

Yoshitaka Sekido is affiliated with Nagoya University in Japan and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields, with a notable focus on pulmonary and respiratory medicine, molecular biology, cell biology, oncology, and biomedical engineering.

The primary topics covered in Yoshitaka Sekido's research include occupational and environmental lung diseases, Hippo pathway signaling and YAP/TAZ, pleural and pulmonary diseases, medical imaging and pathology studies, ferroptosis and cancer prognosis, cellular mechanics and interactions, and trace elements in health.

Frequent coauthors collaborating with Yoshitaka Sekido include:

  • Tatsuhiro Sato
  • Satomi Mukai
  • Shinya Toyokuni
  • Ken Akao
  • Li Jiang

Yoshitaka Sekido has published regularly in several scientific journals, with frequent appearances in these venues:

  • Cancer Science
  • Journal of Thoracic Oncology
  • Pathology International
  • Molecular Cancer Therapeutics
  • QJM

Recent papers authored or coauthored by Yoshitaka Sekido highlight their focus on cancer and molecular pathways involved in disease progression:

  • "Lysosomal nitric oxide determines transition from autophagy to ferroptosis after exposure to plasma-activated Ringer's lactate," 2021, Redox Biology
  • "Enhanced anti-tumor efficacy of IL-7/CCL19-producing human CAR-T cells in orthotopic and patient-derived xenograft tumor models," 2021, Cancer Immunology Immunotherapy
  • "NF2 alteration in mesothelioma," 2023, Frontiers in Toxicology
  • "PCBP2 knockdown promotes ferroptosis in malignant mesothelioma," 2022, Pathology International
  • "Elaborate cooperation of poly(rC)-binding proteins 1/2 and glutathione in ferroptosis induced by plasma-activated Ringer's lactate," 2024, Free Radical Biology and Medicine

The research carried out by Sekido reflects a strong interest in the mechanisms of cancer biology, particularly mesothelioma, and the role of cellular processes such as ferroptosis. Sekido's work also engages with tumor immunology, molecular signaling pathways, and pathology, contributing to a multidimensional understanding of these areas within medical science.

Best Publications

  • A Polycistronic MicroRNA Cluster, miR-17-92, Is Overexpressed in Human Lung Cancers and Enhances Cell Proliferation

    Yoji Hayashita;Hirotaka Osada;Yoshio Tatematsu;Hideki Yamada

  • Epigenetic Inactivation of RASSF1A in Lung and Breast Cancers and Malignant Phenotype Suppression

    David G. Burbee;Eva Forgacs;Sabine Zöchbauer-Müller;Latha Shivakumar

  • BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

    David E. Jensen;Monja Proctor;Sandra T. Marquis;Heather Perry Gardner

  • Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

    Yutaka Kondo;Lanlan Shen;Alfred S. Cheng;Alfred S. Cheng;Saira Ahmed

  • Integrative Molecular Characterization of Malignant Pleural Mesothelioma

    Julija Hmeljak;Francisco Sanchez-Vega;Katherine A. Hoadley;Juliann Shih

  • Molecular Genetics of Lung Cancer

    Yoshitaka Sekido;Kwun M. Fong;John D. Minna

  • Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers.

    Ryoichi Onozato;Takayuki Kosaka;Hiroyuki Kuwano;Yoshitaka Sekido

  • Progress in understanding the molecular pathogenesis of human lung cancer

    Yoshitaka Sekido;Kwun M. Fong;John D. Minna

  • YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes

    T Mizuno;H Murakami;M Fujii;F Ishiguro

  • Epithelial to mesenchymal transition in an epidermal growth factor receptor-mutant lung cancer cell line with acquired resistance to erlotinib.

    Kenichi Suda;Kenji Tomizawa;Makiko Fujii;Hideki Murakami

  • LATS2 is a tumor suppressor gene of malignant mesothelioma.

    Hideki Murakami;Tetsuya Mizuno;Tetsuo Taniguchi;Makiko Fujii

  • Molecular pathogenesis of malignant mesothelioma.

    Yoshitaka Sekido

  • Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B

    Yoshio Tomizawa;Yoshitaka Sekido;Yoshitaka Sekido;Masashi Kondo;Boning Gao

  • Reciprocal and Complementary Role of MET Amplification and EGFR T790M Mutation in Acquired Resistance to Kinase Inhibitors in Lung Cancer

    Kenichi Suda;Isao Murakami;Tatsuya Katayama;Kenji Tomizawa

  • Lineage-Specific Dependency of Lung Adenocarcinomas on the Lung Development Regulator TTF-1

    Hisaaki Tanaka;Hisaaki Tanaka;Kiyoshi Yanagisawa;Keiko Shinjo;Ayumu Taguchi

  • Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells.

    Yutaka Kondo;Lanlan Shen;Saira Ahmed;Yanis Boumber

  • Mutation analysis of the PTEN/MMAC1 gene in lung cancer

    Eva Forgacs;Eric J. Biesterveld;Yoshitaka Sekido;Yoshitaka Sekido;Kwun Fong

  • Preferential Expression of c-kit Protooncogene Transcripts in Small Cell Lung Cancer

    Yoshitaka Sekido;Yuichi Obata;Ryuzo Ueda;Toyoaki Hida

  • Functional Properties of a New Voltage-dependent Calcium Channel α2δ Auxiliary Subunit Gene (CACNA2D2)

    Boning Gao;Yoshitaka Sekido;Anton Maximov;Mohamad Saad

  • EGFR-TKI resistance due to BIM polymorphism can be circumvented in combination with HDAC inhibition.

    Takayuki Nakagawa;Shinji Takeuchi;Tadaaki Yamada;Hiromichi Ebi

Frequent Co-Authors

Yoshinori Hasegawa
Yoshinori Hasegawa Nagoya University
Kaoru Shimokata
Kaoru Shimokata Nagoya University
John D. Minna
John D. Minna The University of Texas Southwestern Medical Center
Yasushi Yatabe
Yasushi Yatabe Nagoya University
Shinya Toyokuni
Shinya Toyokuni Nagoya University
Tetsuya Mitsudomi
Tetsuya Mitsudomi Kindai University
Takashi Takahashi
Takashi Takahashi Nagoya University
Adi F. Gazdar
Adi F. Gazdar The University of Texas Southwestern Medical Center
Masahide Takahashi
Masahide Takahashi Nagoya University
Saburo Sone
Saburo Sone University of Tokushima

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