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Medicine

D-Index
163
Citations
152967
World Ranking
669
National Ranking
385

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

George A. Calin is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans key areas within biochemistry, genetics, molecular biology, and medicine, reflecting a broad focus on cancer biology and molecular mechanisms.

The main fields of study for George A. Calin include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, the scientist's work covers several subfields, prominently:

  • Molecular Biology
  • Cancer Research
  • Oncology
  • Epidemiology
  • Genetics

Their research topics concentrate on cancer-related molecular mechanisms and disease regulation, with a particular emphasis on non-coding RNAs and cancer biology. The main topics of their work involve:

  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Breast Cancer Treatment Studies
  • Breast Lesions and Carcinomas
  • Extracellular vesicles in disease
  • Cancer Genomics and Diagnostics

George A. Calin has contributed to multiple recent publications reflecting their areas of expertise:

  • Loss of p53 drives neuron reprogramming in head and neck cancer (2020, Nature)
  • GATA3 as a master regulator for interactions of tumor-associated macrophages with high-grade serous ovarian carcinoma (2020, Cellular Signalling)
  • Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer (2020, Gut)
  • The Long Non-Coding RNA Prader Willi/Angelman Region RNA5 (PAR5) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity (2020, Cancers)
  • Long non-coding RNA uc.291 controls epithelial differentiation by interfering with the ACTL6A/BAF complex (2020, EMBO Reports)

Frequently published venues for George A. Calin's work include:

  • Cancer Research
  • Cancers
  • Research Square (Research Square)
  • Nature
  • Cellular Signalling

The scientist has collaborated often with several co-authors, notably:

  • Mihnea P. Dragomir
  • Cristina Ivan
  • Recep Bayraktar
  • Bülent Özpolat
  • Xinna Zhang

George A. Calin was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2020.

Best Publications

  • MicroRNA signatures in human cancers

    George A. Calin;Carlo M. Croce

  • A microRNA expression signature of human solid tumors defines cancer gene targets

    Stefano Volinia;George A. Calin;Chang Gong Liu;Stefan Ambs

  • Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

    George Adrian Calin;Calin Dan Dumitru;Masayoshi Shimizu;Roberta Bichi

  • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

    George Adrian Calin;Cinzia Sevignani;Calin Dan Dumitru;Terry Hyslop

  • MicroRNA gene expression deregulation in human breast cancer.

    Marilena V. Iorio;Manuela Ferracin;Chang Gong Liu;Angelo Veronese

  • miR-15 and miR-16 induce apoptosis by targeting BCL2.

    Amelia Cimmino;George Adrian Calin;Muller Fabbri;Marilena V. Iorio

  • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

    Nozomu Yanaihara;Natasha Caplen;Elise Bowman;Masahiro Seike

  • A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia

    George Adrian Calin;Manuela Ferracin;Manuela Ferracin;Amelia Cimmino;Gianpiero Di Leva

  • MicroRNAs in Cancer.

    Ramiro Garzon;George A. Calin;Carlo M. Croce

  • MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma

    Aaron J. Schetter;Suet Yi Leung;Jane J. Sohn;Krista A. Zanetti

  • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B.

    Muller Fabbri;Ramiro Garzon;Amelia Cimmino;Amelia Cimmino;Zhongfa Liu

  • MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

    George Adrian Calin;Chang Gong Liu;Cinzia Sevignani;Manuela Ferracin

  • miRNAs, cancer, and stem cell division.

    Carlo M. Croce;George A. Calin

  • MicroRNAs in body fluids—the mix of hormones and biomarkers

    Maria Angelica Cortez;Carlos E. Bueso-Ramos;Jana Ferdin;Gabriel Lopez-Berestein

  • Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-α Stimulation and Their Possible Roles in Regulating the Response to Endotoxin Shock

    Esmerina Tili;Jean-Jacques Michaille;Jean-Jacques Michaille;Amelia Cimino;Stefan Costinean

  • Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis.

    Sonia A. Melo;Hikaru Sugimoto;Hikaru Sugimoto;Joyce T. O’Connell;Noritoshi Kato

  • The role of microRNA genes in papillary thyroid carcinoma

    Hulling He;Krystian Jazdzewski;Wei Li;Sandya Liyanarachchi

  • MicroRNA-Cancer Connection: The Beginning of a New Tale

    G. A. Calin;C. M. Croce

  • MicroRNAs and other non-coding RNAs as targets for anticancer drug development

    Hui Ling;Muller Fabbri;George A. Calin

  • A microRNA DNA methylation signature for human cancer metastasis

    Amaia Lujambio;George A. Calin;Alberto Villanueva;Santiago Ropero

Frequent Co-Authors

Carlo M. Croce
Carlo M. Croce The Ohio State University
Stefano Volinia
Stefano Volinia University of Ferrara
Massimo Negrini
Massimo Negrini University of Ferrara
Ioana Berindan-Neagoe
Ioana Berindan-Neagoe Iuliu Hațieganu University of Medicine and Pharmacy
Anil K. Sood
Anil K. Sood The University of Texas MD Anderson Cancer Center
Gabriel Lopez-Berestein
Gabriel Lopez-Berestein The University of Texas MD Anderson Cancer Center
Cristian Rodriguez-Aguayo
Cristian Rodriguez-Aguayo The University of Texas MD Anderson Cancer Center
Michael J. Keating
Michael J. Keating The University of Texas MD Anderson Cancer Center
Hansjuerg Alder
Hansjuerg Alder The Ohio State University
Thomas J. Kipps
Thomas J. Kipps University of California, San Diego

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