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Medicine

D-Index
116
Citations
45539
World Ranking
4385
National Ranking
2397

Overview

Ajay Goel is affiliated with City Of Hope National Medical Center in the United States, focusing on research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their published work spans molecular biology, oncology, cancer research, surgery, and pulmonary and respiratory medicine.

The scientist's main research topics include:

  • Cancer-related molecular mechanisms research
  • Genetic factors in colorectal cancer
  • RNA modifications and cancer
  • Pancreatic and Hepatic Oncology Research
  • Colorectal Cancer Treatments and Studies
  • MicroRNA in disease regulation
  • Cancer Genomics and Diagnostics

Ajay Goel's research has been featured frequently in several scientific journals, with notable publications appearing in:

  • Gastroenterology (49 publications)
  • Cancer Research (35 publications)
  • British Journal of Cancer (10 publications)
  • Molecular Cancer (9 publications)
  • Carcinogenesis (7 publications)

Recent notable papers include:

  • "Epigenetics of colorectal cancer: biomarker and therapeutic potential," published in 2020 in Nature Reviews Gastroenterology & Hepatology
  • "Non-coding RNAs and potential therapeutic targeting in cancer," published in 2020 in Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • "Curcumin and colorectal cancer: An update and current perspective on this natural medicine," published in 2020 in Seminars in Cancer Biology
  • "A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation," published in 2020 in Nature Communications
  • "Gut Microbiome Components Predict Response to Neoadjuvant Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer: A Prospective, Longitudinal Study," published in 2020 in Clinical Cancer Research

Frequent coauthors who have collaborated extensively with Ajay Goel include:

  • Caiming Xu (38 co-authored works)
  • Yasuhiro Kodera (25 co-authored works)
  • Mitsuo Shimada (20 co-authored works)
  • Yusuke Kinugasa (19 co-authored works)
  • Yuma Wada (17 co-authored works)

Best Publications

  • Curcumin as “Curecumin”: From kitchen to clinic

    Ajay Goel;Ajaikumar B. Kunnumakkara;Bharat B. Aggarwal

  • Microsatellite Instability in Colorectal Cancer

    C. Richard Boland;Ajay Goel

  • Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21

    Yongzhi Yang;Yongzhi Yang;Wenhao Weng;Wenhao Weng;Junjie Peng;Leiming Hong

  • Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers

    Yoshinaga Okugawa;William M. Grady;William M. Grady;Ajay Goel

  • A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis.

    Binu Chandran;Ajay Goel

  • Epigenetics of colorectal cancer: biomarker and therapeutic potential.

    Gerhard Jung;Eva Hernández-Illán;Leticia Moreira;Francesc Balaguer

  • MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis

    Keun Hur;Yuji Toiyama;Masanobu Takahashi;Francesc Balaguer

  • Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.

    Ajay Goel;Bharat B. Aggarwal

  • Molecular classification and correlates in colorectal cancer.

    Shuji Ogino;Shuji Ogino;Ajay Goel

  • Cancer chemoprevention by dietary polyphenols: promising role for epigenetics.

    Alexander Link;Francesc Balaguer;Francesc Balaguer;Ajay Goel

  • Serum miR-21 as a Diagnostic and Prognostic Biomarker in Colorectal Cancer

    Yuji Toiyama;Masanobu Takahashi;Keun Hur;Takeshi Nagasaka

  • Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer.

    John M. Carethers;E.Julieta Smith;Cynthia A. Behling;Lanchinh Nguyen

  • Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells.

    Ajay Goel;C.Richard Boland;Dharam P Chauhan

  • Protective effects of zinc on lipid peroxidation, antioxidant enzymes and hepatic histoarchitecture in chlorpyrifos-induced toxicity

    Ajay Goel;Vijayta Dani;D.K. Dhawan

  • BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells

    P Tassone;P Tassone;P Tagliaferri;A Perricelli;S Blotta

  • Fecal MicroRNAs as Novel Biomarkers for Colon Cancer Screening

    Alexander Link;Francesc Balaguer;Francesc Balaguer;Yan Shen;Takeshi Nagasaka

  • Circular RNA ciRS-7—A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer

    Wenhao Weng;Wenhao Weng;Qing Wei;Shusuke Toden;Kazuhiro Yoshida

  • Frequent Inactivation of PTEN by Promoter Hypermethylation in Microsatellite Instability-High Sporadic Colorectal Cancers

    Ajay Goel;Christian N. Arnold;Christian N. Arnold;Donna Niedzwiecki;John M. Carethers;John M. Carethers

  • The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer

    Ajay Goel;Takeshi Nagasaka;Christian N. Arnold;Toru Inoue

  • Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis

    Francesc Balaguer;Alexander Link;Alexander Link;Juan Jose Lozano;Miriam Cuatrecasas

Frequent Co-Authors

C. Richard Boland
C. Richard Boland University of California, San Diego
Toshiyoshi Fujiwara
Toshiyoshi Fujiwara Okayama University
Hideo Baba
Hideo Baba Kumamoto University
Antoni Castells
Antoni Castells University of Barcelona
Yasuhiro Kodera
Yasuhiro Kodera Nagoya University
Luis Bujanda
Luis Bujanda University of the Basque Country
Mehdi Shakibaei
Mehdi Shakibaei Ludwig-Maximilians-Universität München
Robert J. Mayer
Robert J. Mayer Dana-Farber Cancer Institute
Monica M. Bertagnolli
Monica M. Bertagnolli Brigham and Women's Hospital
Donna Niedzwiecki
Donna Niedzwiecki Duke University

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