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Biology and Biochemistry

D-Index
72
Citations
20695
World Ranking
6233
National Ranking
2932

Overview

William M. Grady is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research focuses primarily on fields related to medicine, with significant contributions to biochemistry, genetics, and molecular biology. Within these domains, their work spans oncology, molecular biology, surgery, pathology and forensic medicine, and pulmonary and respiratory medicine.

The main topics addressed in their research include:

  • Genetic factors in colorectal cancer
  • Colorectal cancer screening and detection
  • Gastric cancer management and outcomes
  • Epigenetics and DNA methylation
  • Esophageal cancer research and treatment
  • Cancer genomics and diagnostics
  • Colorectal cancer treatments and studies

William M. Grady has published extensively in a variety of venues. Notable publication venues include:

  • Gastroenterology
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The American Journal of Gastroenterology
  • Cancer Epidemiology Biomarkers & Prevention

Their recent papers include:

  • "Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps," 2021, Cell
  • "A Cell-free DNA Blood-Based Test for Colorectal Cancer Screening," 2024, New England Journal of Medicine
  • "Epigenetic Alterations in the Gastrointestinal Tract: Current and Emerging Use for Biomarkers of Cancer," 2020, Gastroenterology
  • "NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 1.2021," 2021, PubMed
  • "Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer," 2021, Cell Host & Microbe

Frequent co-authors who have collaborated with William M. Grady include:

  • Christopher I. Li
  • Ming Yu
  • Cornelia M. Ulrich
  • Biljana Gigic
  • David Shibata

Best Publications

  • Genomic and Epigenetic Instability in Colorectal Cancer Pathogenesis

    William M. Grady;William M. Grady;John M. Carethers;John M. Carethers

  • A randomized trial of rectal indomethacin to prevent post-ERCP pancreatitis

    B. Joseph Elmunzer;James M. Scheiman;Glen A. Lehman;Amitabh Chak

  • Epigenetics and colorectal cancer

    Victoria Valinluck Lao;William M. Grady

  • Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers

    Yoshinaga Okugawa;William M. Grady;William M. Grady;Ajay Goel

  • Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer.

    William M. Grady;Joseph Willis;Parry J. Guilford;Anita K. Dunbier

  • Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci.

    Mandana Veiseh;Patrik Gabikian;S-Bahram Bahrami;Omid Veiseh

  • Discovery of common and rare genetic risk variants for colorectal cancer

    Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

  • Genetic Mechanisms of Immune Evasion in Colorectal Cancer

    Catherine S. Grasso;Marios Giannakis;Marios Giannakis;Daniel K. Wells;Tsuyoshi Hamada

  • KrasG12D and Smad4/Dpc4 Haploinsufficiency Cooperate to Induce Mucinous Cystic Neoplasms and Invasive Adenocarcinoma of the Pancreas

    Kamel Izeradjene;Chelsea Combs;Melissa Best;Aarthi Gopinathan

  • Colorectal cancer molecular biology moves into clinical practice

    Colin C Pritchard;William M Grady

  • Actionable exomic incidental findings in 6503 participants: challenges of variant classification

    Laura M. Amendola;Michael O. Dorschner;Peggy D. Robertson;Joseph S. Salama

  • Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer.

    W. M. Grady;R. K. Parkin;P. S. Mitchell;J. H. Lee

  • E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer

    Parry J. Guilford;Justin B W Hopkins;William M. Grady;Sanford D. Markowitz

  • Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

    Samir Gupta;Dawn Provenzale;Xavier Llor;Amy L. Halverson

  • Gastric cancer: New genetic developments

    Henry T. Lynch;William Grady;Gianpaolo Suriano;Gianpaolo Suriano;David Huntsman

  • Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer

    Colin C. Pritchard;Colm Morrissey;Akash Kumar;Xiaotun Zhang

  • Genetic/familial high-risk assessment: Colorectal version 1.2016: Clinical practice guidelines in oncology

    Dawn Provenzale;Samir Gupta;Dennis J. Ahnen;Travis Bray

  • Detection of aberrantly methylated hMLH1 promoter DNA in the serum of patients with microsatellite unstable colon cancer

    William M. Grady;Ashwani Raiput;James D. Lutterbaugh;Sanford D. Markowitz

  • Abstract PR03: Genetic mechanisms of immune evasion in colorectal cancer

    Marios Giannakis;Catherine Grasso;Daniel Wells;Tsuyoshi Hamada

  • Discovery of common and rare genetic risk variants for colorectal cancer

    Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

Frequent Co-Authors

Amitabh Chak
Amitabh Chak Case Western Reserve University
Cornelia M. Ulrich
Cornelia M. Ulrich University of Utah
Sanford D. Markowitz
Sanford D. Markowitz Case Western Reserve University
Gary W. Falk
Gary W. Falk University of Pennsylvania
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
John D. Potter
John D. Potter Massey University
Daniel D. Buchanan
Daniel D. Buchanan University of Melbourne
Christopher I. Li
Christopher I. Li Fred Hutchinson Cancer Research Center
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Ulrike Peters
Ulrike Peters University of Washington

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