What is she best known for?
The fields of study she is best known for:
- Gene
- Internal medicine
- DNA
Katherine A. High mainly investigates Genetic enhancement, Immunology, Transgene, Factor IX and Virus.
Her work on Genetic transfer as part of general Genetic enhancement study is frequently linked to Cis-trans-Isomerases, therefore connecting diverse disciplines of science.
Immune system is the focus of her Immunology research.
The Transgene study combines topics in areas such as Genome editing and Intramuscular injection.
Her Factor IX research includes elements of Gene expression, Viral vector, Partial thromboplastin time and Skeletal muscle.
Katherine A. High combines subjects such as Cell and Recombinant DNA with her study of Virus.
Her most cited work include:
- Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis (1779 citations)
- Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis (1779 citations)
- Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response (1606 citations)
What are the main themes of her work throughout her whole career to date?
Her primary scientific interests are in Genetic enhancement, Factor IX, Immunology, Molecular biology and Virology.
Her research integrates issues of Transgene, Bioinformatics, Vector, Viral vector and Disease in her study of Genetic enhancement.
As a part of the same scientific study, Katherine A. High usually deals with the Factor IX, concentrating on Genetic transfer and frequently concerns with Coagulopathy.
Immunology is frequently linked to In vivo in her study.
Her study looks at the relationship between Molecular biology and topics such as Transduction, which overlap with Cell biology.
Katherine A. High has researched Virology in several fields, including Epitope, Cytotoxic T cell and CD8.
She most often published in these fields:
- Genetic enhancement (50.10%)
- Factor IX (46.86%)
- Immunology (48.00%)
What were the highlights of her more recent work (between 2012-2021)?
- Genetic enhancement (50.10%)
- Immunology (48.00%)
- Transgene (32.57%)
In recent papers she was focusing on the following fields of study:
Genetic enhancement, Immunology, Transgene, Virology and Molecular biology are her primary areas of study.
Her Genetic enhancement research is multidisciplinary, incorporating elements of Clinical trial, Bioinformatics, Vector, Factor IX and Disease.
Katherine A. High works mostly in the field of Factor IX, limiting it down to topics relating to Expression cassette and, in certain cases, Viral vector, as a part of the same area of interest.
As part of the same scientific family, Katherine A. High usually focuses on Immunology, concentrating on Adeno-associated virus and intersecting with Immunosuppression.
Her Transgene research integrates issues from Computational biology and Cell biology.
The concepts of her Virology study are interwoven with issues in Cytotoxic T cell, Antibody and Antigen.
Between 2012 and 2021, her most popular works were:
- Long-term safety and efficacy of factor IX gene therapy in hemophilia B (772 citations)
- Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial (660 citations)
- Gene therapy comes of age. (506 citations)
In her most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- DNA
Her primary areas of investigation include Genetic enhancement, Transgene, Immunology, Virus and Clinical trial.
Her Genetic enhancement study integrates concerns from other disciplines, such as Vector, Disease and Bioinformatics.
Katherine A. High studied Transgene and Internal medicine that intersect with Endocrinology and Diabetes mellitus.
All of her Immunology and Immune system and T cell investigations are sub-components of the entire Immunology study.
The various areas that she examines in her Virus study include Antibody and Adeno-associated virus.
She interconnects Factor IX and Immune tolerance in the investigation of issues within Adeno-associated virus.
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