World's Best Scientists 2026 revealed!

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Medicine

D-Index
81
Citations
22504
World Ranking
16719
National Ranking
527

Overview

Hiromu Suzuki is affiliated with Sapporo Medical University in Japan and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields, including molecular biology, cancer research, pathology and forensic medicine, oncology, and pulmonary and respiratory medicine.

Their research focuses on various topics, notably genetic factors in colorectal cancer, cancer-related molecular mechanisms, colorectal cancer treatments and studies, epigenetics and DNA methylation, gastric cancer management and outcomes, cancer genomics and diagnostics, and colorectal cancer screening and detection.

Hiromu Suzuki has published in several frequent venues, with notable contributions to Cancer Science, Scientific Reports, Cancer Medicine, Genes Chromosomes and Cancer, and Pathology International.

Recent publications include:

  • "Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis" (2021) in Cell Death Discovery
  • "Upregulation of adipocyte enhancer-binding protein 1 in endothelial cells promotes tumor angiogenesis in colorectal cancer" (2020) in Cancer Science
  • "Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer" (2022) in The Journal of Pathology
  • "A novel risk stratification model based on the Children's Hepatic Tumours International Collaboration-Hepatoblastoma Stratification and deoxyribonucleic acid methylation analysis for hepatoblastoma" (2022) in European Journal of Cancer
  • "TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells" (2023) in Cell Death and Disease

Frequent co-authors with whom Suzuki has collaborated include:

  • Takeshi Niinuma
  • Tamotsu Sugai
  • Hiroshi Kitajima
  • Eiichiro Yamamoto
  • Masahiro Kai

The breadth of Hiromu Suzuki's research demonstrates a strong engagement with molecular biology and cancer research, particularly in understanding genetic and molecular mechanisms underlying colorectal and other cancers. Their work intersects clinical oncology and molecular pathology, emphasizing areas such as DNA methylation and cancer genomics for diagnostic and therapeutic insights.

Best Publications

  • Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

    Hiromu Suzuki;Hiromu Suzuki;D. Neil Watkins;Kam Wing Jair;Kornel E. Schuebel

  • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

    Hiromu Suzuki;Edward Gabrielson;Edward Gabrielson;Wei Chen;Wei Chen;Ramaswamy Anbazhagan;Ramaswamy Anbazhagan

  • Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.

    Minoru Toyota;Hiromu Suzuki;Yasushi Sasaki;Reo Maruyama

  • Aberrant Methylation in Gastric Cancer Associated with the CpG Island Methylator Phenotype

    Minoru Toyota;Nita Ahuja;Hiromu Suzuki;Fumio Itoh

  • Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors

    Takeshi Niinuma;Hiromu Suzuki;Masanori Nojima;Katsuhiko Nosho

  • Fusobacterium in colonic flora and molecular features of colorectal carcinoma

    Tomomitsu Tahara;Tomomitsu Tahara;Eiichiro Yamamoto;Hiromu Suzuki;Reo Maruyama

  • Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.

    Kornel E. Schuebel;Wei Chen;Leslie Cope;Sabine C. Glöckner

  • Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis

    Kei Mitsuhashi;Katsuhiko Nosho;Yasutaka Sukawa;Yasutaka Matsunaga

  • GATA-4 and GATA-5 Transcription Factor Genes and Potential Downstream Antitumor Target Genes Are Epigenetically Silenced in Colorectal and Gastric Cancer

    Yoshimitsu Akiyama;Neil Watkins;Hiromu Suzuki;Kam Wing Jair

  • Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer

    H Suzuki;M Toyota;M Toyota;H Caraway;E Gabrielson

  • Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma.

    Norikazu Iwata;Hiroyuki Yamamoto;Shigeru Sasaki;Fumio Itoh

  • DNA methylation and microRNA dysregulation in cancer.

    Hiromu Suzuki;Reo Maruyama;Eiichiro Yamamoto;Masahiro Kai

  • Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway

    Miki Ito;Shinichi Kanno;Katsuhiko Nosho;Yasutaka Sukawa

  • Array-based genomic resequencing of human leukemia

    Y Yamashita;J Yuan;I Suetake;H Suzuki

  • Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.

    M Nojima;H Suzuki;M Toyota;M Toyota;Y Watanabe

  • De novo CpG Island Methylation in Human Cancer Cells

    Kam Wing Jair;Kurtis E. Bachman;Hiromu Suzuki;Angela H. Ting

  • Inactivation of the 14-3-3 σ Gene Is Associated with 5′ CpG Island Hypermethylation in Human Cancers

    Hiromu Suzuki;Fumio Itoh;Minoru Toyota;Takefumi Kikuchi

  • Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.

    Hironobu Sato;Hiromu Suzuki;Minoru Toyota;Masanori Nojima

  • The p53 gene is very frequently mutated in small-cell lung cancer with a distinct nucleotide substitution pattern.

    Takahashi T;Suzuki H;Hida T;Sekido Y

  • Epigenetic inactivation of CHFR in human tumors

    Minoru Toyota;Yasushi Sasaki;Ayumi Satoh;Kazuhiro Ogi

Frequent Co-Authors

Minoru Toyota
Minoru Toyota Sapporo Medical University
Kohzoh Imai
Kohzoh Imai University of Tokyo
Yasuhisa Shinomura
Yasuhisa Shinomura Sapporo Medical University
Takashi Tokino
Takashi Tokino Sapporo Medical University
Hiroyuki Yamamoto
Hiroyuki Yamamoto St. Marianna University School of Medicine
Katsuhiko Nosho
Katsuhiko Nosho Sapporo Medical University
Koichi Hirata
Koichi Hirata Sapporo Medical University
Stephen B. Baylin
Stephen B. Baylin Johns Hopkins University
Jean Pierre J. Issa
Jean Pierre J. Issa Temple University
Yuji Hinoda
Yuji Hinoda Yamaguchi University

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