D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 86 Citations 24,981 459 World Ranking 9238 National Ranking 260

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

Cancer research, Pathology, Colorectal cancer, Cancer and Genetics are his primary areas of study. Hiroyuki Yamamoto has researched Cancer research in several fields, including Methylation, DNA methylation, Carcinogenesis, Microsatellite instability and DNA mismatch repair. His work deals with themes such as Epigenetics and Immunology, which intersect with DNA methylation.

His study in DNA mismatch repair is interdisciplinary in nature, drawing from both Gastrointestinal cancer and Frameshift mutation. He interconnects Esophagus, Esophageal disease, Metastasis and Pancreas in the investigation of issues within Pathology. His Colorectal cancer research includes elements of Tumor progression, Malignancy and Disease.

His most cited work include:

  • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. (1241 citations)
  • Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis. (352 citations)
  • Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics. (310 citations)

What are the main themes of his work throughout his whole career to date?

Hiroyuki Yamamoto mainly focuses on Cancer research, Internal medicine, Cancer, Pathology and Colorectal cancer. Hiroyuki Yamamoto combines subjects such as Genetics, DNA methylation, Carcinogenesis, Microsatellite instability and Epigenetics with his study of Cancer research. His Microsatellite instability study incorporates themes from MLH1, DNA mismatch repair and Frameshift mutation.

In his study, microRNA is inextricably linked to Oncology, which falls within the broad field of Internal medicine. His studies in Cancer integrate themes in fields like Mutation and Molecular biology. His research integrates issues of Stomach and Adenocarcinoma in his study of Pathology.

He most often published in these fields:

  • Cancer research (30.63%)
  • Internal medicine (26.08%)
  • Cancer (22.53%)

What were the highlights of his more recent work (between 2014-2021)?

  • Internal medicine (26.08%)
  • Cancer research (30.63%)
  • Cancer (22.53%)

In recent papers he was focusing on the following fields of study:

Hiroyuki Yamamoto mainly investigates Internal medicine, Cancer research, Cancer, Oncology and Pathology. His Internal medicine research incorporates themes from Gastroenterology and Cardiology. His Cancer research research focuses on subjects like Microsatellite instability, which are linked to Predictive marker, DNA mismatch repair and Lynch syndrome.

His work carried out in the field of Cancer brings together such families of science as Helicobacter pylori, DNA methylation, Early detection, Microarray and Stage. His study looks at the relationship between Oncology and topics such as Colorectal cancer, which overlap with EZH2, Surgical oncology, Pancreas and Metastasis. His study in Pathology is interdisciplinary in nature, drawing from both Hepatocellular carcinoma and Adenocarcinoma.

Between 2014 and 2021, his most popular works were:

  • Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer (141 citations)
  • Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway (133 citations)
  • Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis (132 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

Hiroyuki Yamamoto spends much of his time researching Internal medicine, Oncology, Colorectal cancer, KRAS and Gastroenterology. His Internal medicine research focuses on Methylation and how it relates to Early detection, Illumina Methylation Assay, Virus Integration and RNA-Directed DNA Methylation. His biological study spans a wide range of topics, including Rectum, Hepatocellular carcinoma, microRNA, Hepatology and Biomarker.

The concepts of his Colorectal cancer study are interwoven with issues in Acquired immune system, Pancreas, Metastasis, Surgical oncology and FOXP3. While the research belongs to areas of Metastasis, Hiroyuki Yamamoto spends his time largely on the problem of Gene silencing, intersecting his research to questions surrounding Cancer research. Many of his studies involve connections with topics such as Pathology and KRAS.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

Nicholas Rampino;Hiroyuki Yamamoto;Yurij Ionov;Yan Li.
Science (1997)

1747 Citations

Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis.

Masanori;Hiroyuki Yamamoto;Yasushi Adachi;Yumiko Maruyama.
Experimental Biology and Medicine (2006)

568 Citations

Predisposing Factors to Enlargement of Spontaneous Intracerebral Hematoma

S. Kazui;K. Minematsu;H. Yamamoto;T. Sawada.
Stroke (1997)

553 Citations

Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics.

Kohzoh Imai;Hiroyuki Yamamoto.
Carcinogenesis (2008)

476 Citations

Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors

Takeshi Niinuma;Hiromu Suzuki;Masanori Nojima;Katsuhiko Nosho.
Cancer Research (2012)

436 Citations

Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells

H Komano;Y Fujiura;M Kawaguchi;S Matsumoto.
Proceedings of the National Academy of Sciences of the United States of America (1995)

433 Citations

A new conceptualization for Mikulicz's disease as an IgG4-related plasmacytic disease

Motohisa Yamamoto;Hiroki Takahashi;Mikiko Ohara;Chisako Suzuki.
Modern Rheumatology (2006)

428 Citations

Exosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer

T Matsumura;K Sugimachi;H Iinuma;Y Takahashi.
British Journal of Cancer (2015)

409 Citations

Frameshift mutator mutations

Sergei Malkhosyan;Nicholas Rampino;Hiroyuki Yamamoto;Manuel Perucho.
Nature (1996)

407 Citations

BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing

E Domingo;P Laiho;M Ollikainen;M Pinto.
Journal of Medical Genetics (2004)

399 Citations

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