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Molecular Biology

D-Index
64
Citations
27216
World Ranking
1699
National Ranking
857

Overview

Manuel Perucho is affiliated with the Discovery Institute in the United States. Their research focuses primarily on the fields of Biochemistry, Genetics, and Molecular Biology, with specific attention to Genetics, Molecular Biology, Cancer Research, and Cell Biology. The scientist's work covers topics such as Genomics and Rare Diseases, Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Cancer Genomics and Diagnostics, RNA Research and Splicing, Cancer-related Molecular Mechanisms Research, and Molecular Biology Techniques and Applications.

The scientist has contributed to several recent publications. These include the following papers:

  • Stimulated emission depletion (STED) super resolution imaging of RNA- and protein-containing domains in fixed cells, 2020, published in Methods
  • GCAT|Panel, a comprehensive structural variant haplotype map of the Iberian population from high-coverage whole-genome sequencing, 2022, published in Nucleic Acids Research
  • Somatic Hypomethylation of Pericentromeric SST1 Repeats and Tetraploidization in Human Colorectal Cancer Cells, 2021, published in Cancers
  • Somatic hypomethylation of pericentromeric SST1 repeats and tetraploidization in human colorectal cancer cells, 2021, published in bioRxiv (Cold Spring Harbor Laboratory)
  • GCAT|Panel, a comprehensive structural variant haplotype map of the Iberian population from high-coverage whole-genome sequencing, 2021, published in bioRxiv (Cold Spring Harbor Laboratory)

Manuel Perucho frequently collaborates with a group of co-authors, including:

  • Jordi Valls-Margarit
  • Iván Galván-Femenía
  • Daniel Matías-Sánchez
  • Natàlia Blay
  • Montserrat Puiggròs

Their work is often published in several notable venues, such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Methods
  • Nucleic Acids Research
  • Cancers

Best Publications

  • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

    Yurij Ionov;Miguel A. Peinado;Sergei Malkhosyan;Darryl Shibata

  • Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes.

    Concepcion Almoguera;Darryl Shibata;Kathleen Forrester;John Martin

  • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

    Nicholas Rampino;Hiroyuki Yamamoto;Yurij Ionov;Yan Li

  • A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting Highlights and Bethesda Guidelines

    Miguel A Rodriguez-Bigas;C. R. Boland;Stanley R Hamilton;D. E. Henson

  • Detection of high incidence of K- ras oncogenes during human colon tumorigenesis

    Kathleen Forrester;Concepcion Almoguera;Kyuhyung Han;Kyuhyung Han;William E. Grizzle

  • Isolation and Preliminary Characterization of a Human Transforming Gene from T24 Bladder-Carcinoma Cells

    Mitchell Goldfarb;Kenji Shimizu;Manuel Perucho;Michael Wigler

  • Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation.

    Shibata D;Peinado Ma;Ionov Y;Malkhosyan S

  • Human-tumor-derived cell lines contain common and different transforming genes.

    Manuel Perucho;Mitchell Goldfarb;Kenji Shimizu;Concepcion Lama

  • Transformation of mammalian cells with an amplifiable dominant-acting gene

    M. H. Wigler;M. Perucho;D. Kurtz;S. Dana

  • Three human transforming genes are related to the viral ras oncogenes

    Kenji Shimizu;Mitchell Goldfarb;Yolande Suard;Manuel Perucho

  • Genetic and Physical Linkage of Exogenous Sequences in Transformed-Cells

    Manuel Perucho;Douglas Hanahan;Michael Wigler

  • The somatic replication of DNA methylation.

    Michael Wigler;Daniel Levy;Manuel Perucho

  • A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells

    Edward Winter;Fumichiro Yamamoto;Concepcion Almoguera;Manuel Perucho

  • International conference on the healthy effect of virgin olive oil.

    Francisco Perez-Jimenez;G. Alvarez De Cienfuegos;Lina Badimon;G. Barja

  • Frameshift mutator mutations

    Sergei Malkhosyan;Nicholas Rampino;Hiroyuki Yamamoto;Manuel Perucho

  • Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction.

    Miguel A. Peinado;Sergei Malkhosyan;Antonia Velazquez;Manuel Perucho

  • Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.

    Asad Umar;J. C. Boyer;D. C. Thomas;D. C. Nguyen

  • Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line

    Kenji Shimizu;Mitchell Goldfarb;Manuel Perucho;Michael Wigler

  • Cancer of the microsatellite mutator phenotype

    Perucho M

  • Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype

    Hiroyuki Yamamoto;Hisako Sawai;Manuel Perucho

Frequent Co-Authors

Hiroyuki Yamamoto
Hiroyuki Yamamoto St. Marianna University School of Medicine
Michael Wigler
Michael Wigler Cold Spring Harbor Laboratory
Miguel A. Peinado
Miguel A. Peinado Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
Gabriel Capellá
Gabriel Capellá Institut d'Investigació Biomédica de Bellvitge
Mitchell Goldfarb
Mitchell Goldfarb Hunter College
Takao Sekiya
Takao Sekiya National Cancer Research Institute, UK
Jun Yokota
Jun Yokota National Cancer Centre
John C. Reed
John C. Reed Johnson & Johnson (United States)
Michael McClelland
Michael McClelland University of California, Irvine
Alex Y. Strongin
Alex Y. Strongin Sanford Burnham Prebys Medical Discovery Institute

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