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Mitchell Goldfarb

Mitchell Goldfarb

D-Index & Metrics

Molecular Biology

D-Index
64
Citations
22104
World Ranking
1707
National Ranking
862

Overview

Mitchell Goldfarb is affiliated with Hunter College in the United States and specializes in research within the broad field of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology.

Their work encompasses a range of interconnected topics including:

  • Cardiac electrophysiology and arrhythmias
  • Ion channel regulation and function
  • Fibroblast Growth Factor Research
  • Epigenetics and DNA Methylation
  • Genetics and Neurodevelopmental Disorders
  • Ion Channels and Receptors
  • Neuroscience of respiration and sleep

Goldfarb has published in a variety of scientific journals, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The American Journal of Human Genetics
  • Epilepsia
  • Circulation Research
  • The Journal of Physiology

Notable recent papers include:

  • "Fibroblast growth factor homologous factors: canonical and non-canonical mechanisms of action" (2024, The Journal of Physiology)
  • "Missense variants in the N-terminal domain of the A isoform of FHF2/FGF13 cause an X-linked developmental and epileptic encephalopathy" (2020, The American Journal of Human Genetics)
  • "Early onset epilepsy and sudden unexpected death in epilepsy with cardiac arrhythmia in mice carrying the early infantile epileptic encephalopathy 47 gain-of-function FHF1(FGF12) missense mutation" (2021, Epilepsia)
  • "Ionic Mechanisms of Impulse Propagation Failure in the FHF2-Deficient Heart" (2020, Circulation Research)
  • "Enhanced sodium channel inactivation by temperature and FHF2 deficiency blocks heat nociception" (2022, Pain)

Goldfarb collaborates frequently with other researchers in related fields. Notable coauthors include:

  • Christopher Marra
  • Akshay Shekhar
  • David Park
  • Glenn I. Fishman
  • Vasilisa Iatckova

Best Publications

  • Receptor specificity of the fibroblast growth factor family.

    David M. Ornitz;Jingsong Xu;Jennifer S. Colvin;Donald G. McEwen

  • Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity.

    Samuel Davis;Nicholas W. Gale;Thomas H. Aldrich;Peter C. Maisonpierre

  • Requirement of FGF-4 for postimplantation mouse development

    Benjamin Feldman;William Poueymirou;Virginia E. Papaioannou;Thomas M. DeChiara

  • Initiation of Mammalian Liver Development from Endoderm by Fibroblast Growth Factors

    Joonil Jung;Minghua Zheng;Mitchell Goldfarb;Kenneth S. Zaret

  • The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

    Trevor N Stitt;Greg Conn;Martin Goret;Martin Goret;Cary Lai

  • Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change

    Elizabeth Taparowsky;Yolande Suard;Ottavio Fasano;Kenji Shimizu

  • Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin.

    Chiaho Shih;Ben-Zion Shilo;Mitchell P. Goldfarb;Ann Dannenberg

  • Isolation and Preliminary Characterization of a Human Transforming Gene from T24 Bladder-Carcinoma Cells

    Mitchell Goldfarb;Kenji Shimizu;Manuel Perucho;Michael Wigler

  • Structure and activation of the human N-ras gene

    Elizabeth Taparowsky;Kenji Shimizu;Mitchell Goldfarb;Michael Wigler

  • An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors

    Ajay Shrivastava;Czeslaw Radziejewski;Ernest Campbell;Lubomir Kovac

  • Human-tumor-derived cell lines contain common and different transforming genes.

    Manuel Perucho;Mitchell Goldfarb;Kenji Shimizu;Concepcion Lama

  • The Human FGF-5 Oncogene Encodes a Novel Protein Related to Fibroblast Growth Factors

    Xi Zhan;B. Bates;Xiaogao Hu;M. Goldfarb

  • Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins.

    S. Powers;T. Kataoka;O. Fasano;M. Goldfarb

  • Three human transforming genes are related to the viral ras oncogenes

    Kenji Shimizu;Mitchell Goldfarb;Yolande Suard;Manuel Perucho

  • Structure of the Ki- ras gene of the human lung carcinoma cell line Calu-1

    Kenji Shimizu;Kenji Shimizu;Daniel Birnbaum;Mary Ann Ruley;Ottavio Fasano

  • Functional homology of mammalian and yeast RAS genes

    Tohru Kataoka;Scott Powers;Scott Cameron;Ottavio Fasano

  • Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line

    Kenji Shimizu;Mitchell Goldfarb;Manuel Perucho;Michael Wigler

  • Fibroblast Growth Factor (FGF) Homologous Factors Share Structural but Not Functional Homology with FGFs

    Shaun K. Olsen;Meirav Garbi;Niccolo Zampieri;Anna V. Eliseenkova

  • The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins.

    Petros A. Hantzopoulos;Chitra Suri;David J. Glass;Mitchell P. Goldfarb

  • Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis.

    Jean M. Hébert;Claudio Basilico;Mitchell Goldfarb;Olivia Haub

Frequent Co-Authors

George D. Yancopoulos
George D. Yancopoulos Regeneron (United States)
Michael Wigler
Michael Wigler Cold Spring Harbor Laboratory
Elizabeth J. Taparowsky
Elizabeth J. Taparowsky Purdue University West Lafayette
Egidio D'Angelo
Egidio D'Angelo University of Pavia
Manuel Perucho
Manuel Perucho Discovery Institute
David M. Ornitz
David M. Ornitz Washington University in St. Louis
David J. Glass
David J. Glass Regeneron (United States)
Ming-Ming Zhou
Ming-Ming Zhou Icahn School of Medicine at Mount Sinai

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