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Nobuyuki Itoh

Nobuyuki Itoh

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
35946
World Ranking
2654
National Ranking
163

Overview

Nobuyuki Itoh is affiliated with Kyoto University in Japan and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans multiple subfields including molecular biology, surgery, immunology, pulmonary and respiratory medicine, and physiology.

Their work notably focuses on several main topics, including:

  • Fibroblast Growth Factor Research
  • Kruppel-like Factors Research
  • Epigenetics and DNA Methylation
  • Pancreatic Function and Diabetes
  • Genetic Syndromes and Imprinting
  • Ferroptosis and Cancer Prognosis
  • RNA Modifications and Cancer

They have coauthored numerous papers with frequent collaborators such as Morichika Konishi, Yoshimi Nakagawa, Song-iee Han, Kae Kumagai, and Hiroshi Ohno.

Nobuyuki Itoh's recent publications include:

  • "New developments in the biology of fibroblast growth factors" (2022) published in WIREs Mechanisms of Disease
  • "Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition" (2020) published in Cellular and Molecular Gastroenterology and Hepatology
  • "CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms" (2020) published in iScience
  • "BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion" (2024) published in Cell Reports
  • "A secretory protein neudesin regulates splenic red pulp macrophages in erythrophagocytosis and iron recycling" (2024) published in Communications Biology

These articles collectively address topics ranging from fibroblast growth factors and metabolic disease mechanisms to ferroptosis and immune regulation.

Publishing in venues such as WIREs Mechanisms of Disease, Cellular and Molecular Gastroenterology and Hepatology, Cell Reports, iScience, and Communications Biology, their research integrates molecular biology with clinical and physiological insights.

Best Publications

  • Fibroblast growth factors

    David M Ornitz;Nobuyuki Itoh

  • The Fibroblast Growth Factor signaling pathway

    David M. Ornitz;Nobuyuki Itoh

  • Fgf10 is essential for limb and lung formation

    Keisuke Sekine;Hideyo Ohuchi;Masanori Fujiwara;Masahiro Yamasaki

  • Evolution of the Fgf and Fgfr gene families

    Nobuyuki Itoh;David M. Ornitz

  • Identification of a novel FGF, FGF-21, preferentially expressed in the liver.

    Tetsuya Nishimura;Yuhki Nakatake;Morichika Konishi;Nobuyuki Itoh

  • Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

    Savério Bellusci;Justin Grindley;Hisayo Emoto;Nobuyuki Itoh

  • Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27.

    Nobuyuki Itoh;Ken ichi Obata;Noboru Yanaihara;Hiroshi Okamoto

  • Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

    Nobuyuki Itoh;David M. Ornitz

  • Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain.

    Tetsuo Yamashita;Masazumi Yoshioka;Nobuyuki Itoh

  • Adiponectin Mediates the Metabolic Effects of FGF21 on Glucose Homeostasis and Insulin Sensitivity in Mice

    Zhuofeng Lin;Haishan Tian;Karen S.L. Lam;Shaoqiang Lin

  • FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development.

    Hideyo Ohuchi;Yukiko Hori;Masahiro Yamasaki;Hidemitsu Harada

  • Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model

    Yasushi Takagi;Jun Takahashi;Hidemoto Saiki;Asuka Morizane

  • FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis

    Norihiko Ohbayashi;Masaki Shibayama;Yoko Kurotaki;Mayumi Imanishi

  • Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis

    Anil Bhushan;Nobuyuki Itoh;Shigeaki Kato;Jean P. Thiery

  • Functional evolutionary history of the mouse Fgf gene family.

    Nobuyuki Itoh;David M. Ornitz

  • Specific Molecular Interactions of Oversulfated Chondroitin Sulfate E with Various Heparin-binding Growth Factors IMPLICATIONS AS A PHYSIOLOGICAL BINDING PARTNER IN THE BRAIN AND OTHER TISSUES

    Sarama Sathyaseelan Deepa;Yuko Umehara;Shigeki Higashiyama;Nobuyuki Itoh

  • Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver.

    Yuhei Hotta;Hirotoshi Nakamura;Morichika Konishi;Yusuke Murata

  • Structure and Expression of the Rat mRNA Encoding a Novel Member of the Fibroblast Growth Factor Family

    Masahiro Yamasaki;Ayumi Miyake;Shuzou Tagashira;Nobuyuki Itoh

  • Sclerostin Is a Novel Secreted Osteoclast-derived Bone Morphogenetic Protein Antagonist with Unique Ligand Specificity

    Naoki Kusu;Johanna Laurikkala;Mayumi Imanishi;Hiroko Usui

  • Characterization of growth factor-binding structures in heparin/heparan sulfate using an octasaccharide library.

    Satoko Ashikari-Hada;Hiroko Habuchi;Yutaka Kariya;Nobuyuki Itoh

Frequent Co-Authors

Toshisuke Kawasaki
Toshisuke Kawasaki Ritsumeikan University
Hideyo Ohuchi
Hideyo Ohuchi Okayama University
Shigeaki Kato
Shigeaki Kato University of Tokyo
Saverio Bellusci
Saverio Bellusci University of Giessen
David M. Ornitz
David M. Ornitz Washington University in St. Louis
Irma Thesleff
Irma Thesleff University of Helsinki
Kazuyuki Sugahara
Kazuyuki Sugahara Hokkaido University
Jean Paul Thiery
Jean Paul Thiery National University of Singapore
Kazuwa Nakao
Kazuwa Nakao Kyoto University
Hiroshi Okamoto
Hiroshi Okamoto University of Tokyo

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