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Medicine

D-Index
120
Citations
49124
World Ranking
3779
National Ranking
34

Overview

Aimin Xu is affiliated with the University of Hong Kong in China and has an extensive research portfolio focusing primarily on medicine and biochemistry, genetics, and molecular biology. Their scholarly activities span multiple interconnected subfields, including molecular biology, physiology, epidemiology, cardiology and cardiovascular medicine, and immunology.

The research conducted by Aimin Xu addresses a range of topics, notably adipose tissue and metabolism, liver disease diagnosis and treatment, adipokines, inflammation, and metabolic diseases. Their work also encompasses fibroblast growth factor research, diet and metabolism studies, Kruppel-like factors research, and the relationship between gut microbiota and health.

Aimin Xu has contributed to a variety of academic venues with repeated publications in prestigious journals. These frequent publication venues include Nature Communications, The Journal of Clinical Endocrinology & Metabolism, Circulation, Advanced Science, and arXiv (Cornell University).

The scientist has collaborated regularly with coauthors such as Karen S.L. Lam, Chi-Ho Lee, Leigang Jin, Erfei Song, and Dewei Ye, with collaboration counts ranging from 13 to 25 joint works.

Significant recent papers authored or coauthored by Aimin Xu include:

  • The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic (2020, Nature Reviews Endocrinology)
  • Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool? (2022, Cell Death and Disease)
  • FGF21-Sirtuin 3 Axis Confers the Protective Effects of Exercise Against Diabetic Cardiomyopathy by Governing Mitochondrial Integrity (2022, Circulation)
  • Predictable modulation of cancer treatment outcomes by the gut microbiota (2020, Microbiome)
  • Decreased Abundance of Akkermansia muciniphila Leads to the Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes (2021, Advanced Science)

Best Publications

  • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

    Aimin Xu;Yu Wang;Hussila Keshaw;Lance Yi Xu

  • Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

    Xinmei Zhang;Dennis C.Y. Yeung;Michal Karpisek;David Stejskal

  • Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome.

    Aimin Xu;Yu Wang;Jian Yu Xu;David Stejskal

  • Lipocalin-2 Is an Inflammatory Marker Closely Associated with Obesity, Insulin Resistance, and Hyperglycemia in Humans

    Yu Wang;Karen S. L. Lam;Edward W. Kraegen;Gary Sweeney

  • Adiponectin Mediates the Metabolic Effects of FGF21 on Glucose Homeostasis and Insulin Sensitivity in Mice

    Zhuofeng Lin;Haishan Tian;Karen S.L. Lam;Shaoqiang Lin

  • Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe−/− Mice

    Jin Li;Shaoqiang Lin;Paul M. Vanhoutte;Connie W. Woo

  • Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes

    Aimin Xu;Aimin Xu;Kok Weng Chan;Ruby L.C. Hoo;Yu Wang;Yu Wang

  • Hydroxylation and Glycosylation of the Four Conserved Lysine Residues in the Collagenous Domain of Adiponectin: POTENTIAL ROLE IN THE MODULATION OF ITS INSULIN-SENSITIZING ACTIVITY

    Yu Wang;Aimin Xu;Catriona Knight;Lance Yi Xu

  • Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilation.

    K. C. B. Tan;A. Xu;W. S. Chow;M. C. W. Lam

  • Adiponectin Inhibits Cell Proliferation by Interacting with Several Growth Factors in an Oligomerization-dependent Manner

    Yu Wang;Karen S L Lam;Jian Yu Xu;Gang Lu

  • Post-translational modifications of adiponectin: mechanisms and functional implications

    Yu Wang;Karen S. L. Lam;Ming-hon Yau;Aimin Xu

  • Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters

    J Graessler;Y Qin;H Zhong;J Zhang

  • Circulating adipocyte-fatty acid binding protein levels predict the development of the metabolic syndrome: a 5-year prospective study.

    Aimin Xu;Annette W.K. Tso;Bernard M.Y. Cheung;Yu Wang

  • Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride.

    Huating Li;Qichen Fang;Fei Gao;Jia Fan

  • Thirty Years of Saying NO: Sources, Fate, Actions, and Misfortunes of the Endothelium-Derived Vasodilator Mediator.

    Paul M. Vanhoutte;Yingzi Zhao;Aimin Xu;Susan W.S. Leung

  • The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic

    Leiluo Geng;Karen S L Lam;Aimin Xu

  • Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice.

    Stephanie A. Shore;Raya D. Terry;Lesley Flynt;Aimin Xu

  • Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice.

    Aimin Xu;Michael C. Lam;Kok Weng Chan;Yu Wang

  • Serum adipocyte fatty acid binding protein as a new biomarker predicting the development of type 2 diabetes: a 10-year prospective study in a Chinese cohort.

    Annette W.K. Tso;Aimin Xu;Pak C. Sham;Nelson M.S. Wat

  • Hypoadiponectinemia as a Predictor for the Development of Hypertension. A 5-Year Prospective Study

    Wing-Sun Chow;Bernard M.Y. Cheung;Annette W.K. Tso;Aimin Xu

Frequent Co-Authors

Karen S.L. Lam
Karen S.L. Lam University of Hong Kong
Yu Wang
Yu Wang University of Hong Kong
Paul M. Vanhoutte
Paul M. Vanhoutte University of Hong Kong
Donghai Wu
Donghai Wu Cornell University
Gary Sweeney
Gary Sweeney York University
Hung-Fat Tse
Hung-Fat Tse University of Hong Kong
Yu Huang
Yu Huang University of California, Los Angeles
Pak C. Sham
Pak C. Sham University of Hong Kong
Garth J. S. Cooper
Garth J. S. Cooper University of Auckland
Weiping Jia
Weiping Jia Shanghai Jiao Tong University

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