World's Best Scientists 2026 revealed!
Paul M. Vanhoutte

Paul M. Vanhoutte

Award Badge
Medicine
China
2023

D-Index & Metrics

Medicine

D-Index
155
Citations
91240
World Ranking
968
National Ranking
5

Research.com Recognitions

  • 2023 - Research.com Medicine in China Leader Award
  • 2022 - Research.com Medicine in China Leader Award
  • 1995 - Member of Academia Europaea

Overview

Paul M. Vanhoutte was affiliated with the University of Hong Kong in China and contributed to several fields within biomedical research. Their work spanned medicine, immunology and microbiology, as well as biochemistry, genetics and molecular biology.

The subfields explored in their research included immunology, molecular biology, pharmacology, cardiology and cardiovascular medicine, and epidemiology. The topics addressed across their publications involved acute ischemic stroke management, neurological disease mechanisms and treatments, metabolomics and mass spectrometry studies, atherosclerosis and cardiovascular diseases, pharmacological effects of natural compounds, receptor mechanisms and signaling, and heart failure treatment and management.

Paul M. Vanhoutte was involved in publications across a number of well-regarded scientific journals. These venues included:

  • European Heart Journal
  • Cardiovascular Research
  • Acta Physiologica
  • Atherosclerosis
  • British Journal of Pharmacology

Their most recent papers comprised the following works:

  • Adipocyte fatty acid-binding protein exacerbates cerebral ischaemia injury by disrupting the blood-brain barrier, 2020, European Heart Journal
  • TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies, 2021, Cardiovascular Research
  • Natriuretic peptides relax human intrarenal arteries through natriuretic peptide receptor type-A recapitulated by soluble guanylyl cyclase agonists, 2020, Acta Physiologica
  • The NO-donor MPC-1011 stimulates angiogenesis and arteriogenesis and improves hindlimb ischemia via a cGMP-dependent pathway involving VEGF and SDF-1α, 2020, Atherosclerosis
  • Major histocompatibility complexes are up-regulated in glomerular endothelial cells via activation of c-Jun N-terminal kinase in 5/6 nephrectomy mice, 2020, British Journal of Pharmacology

The scientist collaborated frequently with several co-authors, including:

  • Margot Crucet
  • Branko Simic
  • Giovanni G. Camici
  • Thomas F. Lüscher
  • Boya Liao

Recognition of Paul M. Vanhoutte's contributions includes election as a Member of Academia Europaea in 1995.

Best Publications

  • Endothelium-derived relaxing and contracting factors.

    Robert F. Furchgott;Paul M. Vanhoutte

  • Flow-induced release of endothelium-derived relaxing factor

    G. M. Rubanyi;J. C. Romero;P. M. Vanhoutte

  • Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor.

    G. M. Rubanyi;P. M. Vanhoutte

  • Endothelial dysfunction in diabetes

    An S De Vriese;Tony J Verbeuren;Johan Van de Voorde;Norbert H Lameire

  • Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture).

    Michel Félétou;Paul M. Vanhoutte

  • Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat.

    T F Lüscher;P M Vanhoutte

  • Endothelium-dependent hyperpolarization of canine coronary smooth muscle.

    Michel Feletou;Paul M. Vanhoutte

  • Endothelial dysfunction and vascular disease

    P. M. Vanhoutte;H. Shimokawa;E. H. C. Tang;M. Feletou

  • Anti-inflammatory actions of steroids: molecular mechanisms

    Peter J. Barnes;Ian Adcock

  • EDHF: bringing the concepts together.

    Rudi Busse;Gillian Edwards;Michel Félétou;Ingrid Fleming

  • Endothelium and control of vascular function. State of the Art lecture.

    P M Vanhoutte

  • Endothelial dysfunction and vascular disease – a 30th anniversary update

    P. M. Vanhoutte;H. Shimokawa;M. Feletou;E. H. C. Tang

  • Modulation of vascular smooth muscle contraction by the endothelium.

    P M Vanhoutte;G M Rubanyi;V M Miller;D S Houston

  • Endothelial dysfunction: from physiology to therapy.

    Jean-Vivien Mombouli;Paul M. Vanhoutte

  • Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium.

    J G De Mey;P M Vanhoutte

  • Vascular nitric oxide: Beyond eNOS

    Yingzi Zhao;Paul M. Vanhoutte;Susan W.S. Leung

  • The Endothelium: Modulator of Cardiovascular Function

    Thomas F. Lüscher;Paul M. Vanhoutte

  • Endothelial dysfunction: the first step toward coronary arteriosclerosis.

    Paul M. Vanhoutte

  • Endothelium-Dependent Hyperpolarization Beyond Nitric Oxide and Cyclic GMP

    Richard A. Cohen;Paul M. Vanhoutte

  • Endothelium-Derived Hyperpolarizing Factor Where Are We Now?

    Michel Félétou;Paul M. Vanhoutte

Frequent Co-Authors

Aimin Xu
Aimin Xu University of Hong Kong
Yu Wang
Yu Wang University of Hong Kong
Hiroaki Shimokawa
Hiroaki Shimokawa Tohoku University
Yu Huang
Yu Huang University of California, Los Angeles
Thomas F. Lüscher
Thomas F. Lüscher University of Zurich
Karen S.L. Lam
Karen S.L. Lam University of Hong Kong
Richard A. Cohen
Richard A. Cohen Boston University

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