World's Best Scientists 2026 revealed!

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Best Female Scientists

D-Index
107
Citations
40504
World Ranking
1022
National Ranking
16

Medicine

D-Index
109
Citations
42175
World Ranking
5803
National Ranking
59

Overview

Karen S.L. Lam is affiliated with the University of Hong Kong in China. Their research activity is primarily situated within the field of medicine, with a strong focus on epidemiology, endocrinology, diabetes and metabolism, molecular biology, surgery, and oncology.

Their work has frequently appeared in several key publication venues, including:

  • Journal of the Endocrine Society
  • The Journal of Clinical Endocrinology & Metabolism
  • Frontiers in Endocrinology
  • Hepatology
  • Cell Reports Medicine

Karen S.L. Lam's recent publications cover topics related to metabolic diseases, inflammation, liver fibrosis, and neurodegenerative conditions. Notable papers include:

  • "The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic" (2020) published in Nature Reviews Endocrinology
  • "Adipocyte fatty acid-binding protein exacerbates cerebral ischaemia injury by disrupting the blood-brain barrier" (2020) published in European Heart Journal
  • "Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer's disease mouse model" (2020) published in Molecular Psychiatry
  • "Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells" (2021) published in Advanced Science
  • "Circulating Thrombospondin-2 as a Novel Fibrosis Biomarker of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes" (2021) published in Diabetes Care

The main topics addressed in their research include:

  • Liver Disease Diagnosis and Treatment
  • Adipokines, Inflammation, and Metabolic Diseases
  • Liver Disease and Transplantation
  • Thyroid Disorders and Treatments
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Metabolism, Diabetes, and Cancer
  • Fibroblast Growth Factor Research

Karen S.L. Lam collaborates frequently with several researchers, reflecting substantial joint contributions in their field. Their frequent coauthors include:

  • Chi-Ho Lee
  • David Tak Wai Lui
  • Aimin Xu
  • Yu Cho Woo
  • Carol Ho-Yan Fong

Best Publications

  • Prevalence, Awareness, Treatment, and Control of Hypertension Among United States Adults 1999–2004

    Kwok Leung Ong;Bernard M.Y. Cheung;Yu Bun Man;Chu Pak Lau

  • Obstructive sleep apnea is independently associated with insulin resistance.

    Mary S. M. Ip;Bing Lam;Matthew M. T. Ng;Wah Kit Lam

  • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

    Aimin Xu;Yu Wang;Hussila Keshaw;Lance Yi Xu

  • Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

    Xinmei Zhang;Dennis C.Y. Yeung;Michal Karpisek;David Stejskal

  • Contribution of Polyol Pathway to Diabetes-Induced Oxidative Stress

    Stephen S.M. Chung;Eric C.M. Ho;Karen S.L. Lam;Sookja K. Chung

  • Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome.

    Aimin Xu;Yu Wang;Jian Yu Xu;David Stejskal

  • Lipocalin-2 Is an Inflammatory Marker Closely Associated with Obesity, Insulin Resistance, and Hyperglycemia in Humans

    Yu Wang;Karen S. L. Lam;Edward W. Kraegen;Gary Sweeney

  • Adiponectin Mediates the Metabolic Effects of FGF21 on Glucose Homeostasis and Insulin Sensitivity in Mice

    Zhuofeng Lin;Haishan Tian;Karen S.L. Lam;Shaoqiang Lin

  • Serum leptin and vascular risk factors in obstructive sleep apnea.

    Mary S.M. Ip;Karen S.L. Lam;Chung-man Ho;Kenneth W.T. Tsang

  • Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes

    Aimin Xu;Aimin Xu;Kok Weng Chan;Ruby L.C. Hoo;Yu Wang;Yu Wang

  • Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilation.

    K. C. B. Tan;A. Xu;W. S. Chow;M. C. W. Lam

  • Adiponectin Inhibits Cell Proliferation by Interacting with Several Growth Factors in an Oligomerization-dependent Manner

    Yu Wang;Karen S L Lam;Jian Yu Xu;Gang Lu

  • Post-translational modifications of adiponectin: mechanisms and functional implications

    Yu Wang;Karen S. L. Lam;Ming-hon Yau;Aimin Xu

  • Advanced Glycation End Products and Endothelial Dysfunction in Type 2 Diabetes

    Kathryn C.B. Tan;Wing-Sun Chow;Victor H.G. Ai;Christine Metz

  • Diabetes Prevalence and Therapeutic Target Achievement in the United States, 1999 to 2006

    Bernard M.Y. Cheung;Kwok Leung Ong;Stacey S. Cherny;Pak-Chung Sham

  • Circulating adipocyte-fatty acid binding protein levels predict the development of the metabolic syndrome: a 5-year prospective study.

    Aimin Xu;Annette W.K. Tso;Bernard M.Y. Cheung;Yu Wang

  • The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic

    Leiluo Geng;Karen S L Lam;Aimin Xu

  • Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice.

    Aimin Xu;Michael C. Lam;Kok Weng Chan;Yu Wang

  • Serum adipocyte fatty acid binding protein as a new biomarker predicting the development of type 2 diabetes: a 10-year prospective study in a Chinese cohort.

    Annette W.K. Tso;Aimin Xu;Pak C. Sham;Nelson M.S. Wat

  • Hypoadiponectinemia as a Predictor for the Development of Hypertension. A 5-Year Prospective Study

    Wing-Sun Chow;Bernard M.Y. Cheung;Annette W.K. Tso;Aimin Xu

Frequent Co-Authors

Aimin Xu
Aimin Xu University of Hong Kong
Yu Wang
Yu Wang University of Hong Kong
Pak C. Sham
Pak C. Sham University of Hong Kong
Tai Hing Lam
Tai Hing Lam University of Hong Kong
Hung-Fat Tse
Hung-Fat Tse University of Hong Kong
Christina Wang
Christina Wang Lundquist Institute
Paul M. Vanhoutte
Paul M. Vanhoutte University of Hong Kong
Donghai Wu
Donghai Wu Cornell University
Stacey S. Cherny
Stacey S. Cherny Tel Aviv University
Garth J. S. Cooper
Garth J. S. Cooper University of Auckland

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