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Michael Koomey

Michael Koomey

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
7469
World Ranking
18744
National Ranking
102

Overview

Michael Koomey is affiliated with the University of Oslo in Norway. Their research work spans several fields, primarily focusing on biochemistry, genetics, and molecular biology, with significant contributions to immunology and microbiology.

Their scholarly output includes publications across various topics such as bacterial infections and vaccines, glycosylation and glycoproteins research, genomics and phylogenetics, reproductive tract infections, bacterial biofilms and quorum sensing, antibiotic resistance in bacteria, and studies related to Vibrio bacteria.

Frequent publication venues for their work include mBio, UNC Libraries, Glycobiology, PROTEOMICS, and Frontiers in Cellular and Infection Microbiology.

Their recent papers encompass the following:

  • Allelic polymorphisms in a glycosyltransferase gene shape glycan repertoire in the O-linked protein glycosylation system of Neisseria (2020, Glycobiology)
  • Global Regulatory Pathways Converge To Control Expression of Pseudomonas aeruginosa Type IV Pili (2022, mBio)
  • Sculpting the Bacterial O-Glycoproteome: Functional Analyses of Orthologous Oligosaccharyltransferases with Diverse Targeting Specificities (2022, mBio)
  • Combining FAIMS based glycoproteomics and DIA proteomics reveals widespread proteome alterations in response to glycosylation occupancy changes in Neisseria gonorrhoeae (2024, PROTEOMICS)
  • Sweet complexity: O-linked protein glycosylation in pathogenic Neisseria (2024, Frontiers in Cellular and Infection Microbiology)

Throughout their career, Michael Koomey has frequently collaborated with several researchers, including Chris Hadjineophytou, Jan Haug Anonsen, Bente Børud, Hanne C. Winther-Larsen, and Matthew C. Wolfgang.

Their work covers various subfields such as microbiology, molecular biology, molecular medicine, endocrinology, and spectroscopy. This range reflects a multidisciplinary approach to understanding bacterial systems and molecular mechanisms related to infectious diseases and cellular processes.

Best Publications

  • PilT mutations lead to simultaneous defects in competence for natural transformation and twitching motility in piliated Neisseria gonorrhoeae

    Matthew Wolfgang;Peter Lauer;Hae Sun Park;Laurent Brossay

  • Components and dynamics of fiber formation define a ubiquitous biogenesis pathway for bacterial pili

    Matthew Wolfgang;Matthew Wolfgang;Jos P.M. van Putten;Stanley F. Hayes;David Dorward

  • Effects of recA Mutations on Pilus Antigenic Variation and Phase Transitions in Neisseria gonorrhoeae

    Michael Koomey;Emil C. Gotschlich;Ken Robbins;Sven Bergström

  • General secretion pathway (eps) genes required for toxin secretion and outer membrane biogenesis in Vibrio cholerae.

    M Sandkvist;L O Michel;L P Hough;V M Morales

  • Phase variation of gonococcal protein II: regulation of gene expression by slipped-strand mispairing of a repetitive DNA sequence.

    George L. Murphy;Terry D. Connell;Diana S. Barritt;Michael Koomey

  • Characterization of the pilF-pilD pilus-assembly locus of Neisseria gonorrhoeae

    Nancy E. Freitag;H. Steven Seifert;Michael Koomey

  • Competence for natural transformation in Neisseria gonorrhoeae: components of DNA binding and uptake linked to type IV pilus expression.

    Finn Erik Aas;Matthew C Wolfgang;Stephan Frye;Steven Dunham

  • The product of the pilQ gene is essential for the biogenesis of type IV pili in Neisseria gonorrhoeae.

    Sandra L. Drake;Michael Koomey

  • Identification and characterization of pilG, a highly conserved pilus‐assembly gene in pathogenic Neisseria

    Tone Tønjum;Nancy E. Freitag;Ellen Namork;Michael Koomey

  • PilP, a pilus biogenesis lipoprotein in Neisseria gonorrhoeae, affects expression of PilQ as a high‐molecular‐mass multimer

    Sandra L. Drake;Sara A. Sandstedt;Michael Koomey

  • Suppression of an absolute defect in Type IV pilus biogenesis by loss-of-function mutations in pilT, a twitching motility gene in Neisseria gonorrhoeae

    Matthew Wolfgang;Hae Sun Park;Stanley F. Hayes;Jos P.M. Van Putten

  • Neisseria gonorrhoeae PilV, a type IV pilus-associated protein essential to human epithelial cell adherence

    Hanne C. Winther-Larsen;Finn Terje Hegge;Matthew C Wolfgang;Stanley F. Hayes

  • Broad spectrum O-linked protein glycosylation in the human pathogen Neisseria gonorrhoeae

    Åshild Vik;Finn Erik Aas;Jan Haug Anonsen;Shaun Bilsborough

  • Type IV pilus retraction in pathogenic Neisseria is regulated by the PilC proteins.

    Philippe C Morand;Emmanuelle Bille;Sandrine Morelle;Emmanuel Eugène

  • Porin protein of Neisseria gonorrhoeae: cloning and gene structure

    Emil C. Gotschlich;Michael E. Seiff;Milan S. Blake;Michael Koomey

  • Charged tmRNA but not tmRNA‐mediated proteolysis is essential for Neisseria gonorrhoeae viability

    Canhui Huang;Matthew C. Wolfgang;Matthew C. Wolfgang;Jeffrey Withey;Michael Koomey

  • A force-dependent switch reverses type IV pilus retraction

    Berenike Maier;Michael Koomey;Michael P. Sheetz

  • Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili

    Finn Terje Hegge;Paul G. Hitchen;Finn Erik Aas;Heidi Kristiansen

  • Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance

    Su L. Chiang;Ronald K. Taylor;Michael Koomey;John J. Mekalanos

  • The comP locus of Neisseria gonorrhoeae encodes a type IV prepilin that is dispensable for pilus biogenesis but essential for natural transformation.

    Matthew Wolfgang;Jos P. M. Van Putten;Stanley F. Hayes;Michael Koomey;Michael Koomey

Frequent Co-Authors

Matthew C. Wolfgang
Matthew C. Wolfgang University of North Carolina at Chapel Hill
Jos P. M. van Putten
Jos P. M. van Putten Utrecht University
Stanley F. Hayes
Stanley F. Hayes National Institutes of Health
David W. Dorward
David W. Dorward National Institutes of Health
Åke Forsberg
Åke Forsberg Umeå University
Dominique A. Caugant
Dominique A. Caugant Norwegian Institute of Public Health
Emil C. Gotschlich
Emil C. Gotschlich Rockefeller University
Yonatan H. Grad
Yonatan H. Grad Harvard University
Anne Dell
Anne Dell Imperial College London

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