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Biology and Biochemistry

D-Index
69
Citations
17201
World Ranking
7381
National Ranking
3375

Overview

John D. Aitchison is affiliated with the University of Minnesota in the United States. Their research spans numerous areas within medicine and biochemistry, genetics, and molecular biology, with a significant volume of work focused on molecular biology and infectious diseases.

The scientist's recent research contributions include the following papers:

  • Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis, 2020, Cell Host & Microbe
  • Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape, 2021, eLife
  • Dissecting the Structural Dynamics of the Nuclear Pore Complex, 2020, Molecular Cell
  • Determinants of brain swelling in pediatric and adult cerebral malaria, 2021, JCI Insight
  • Defining the proteolytic landscape during enterovirus infection, 2020, PLoS Pathogens

Their work appears frequently in several publication venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Cell Biology
  • Journal of Biological Chemistry
  • eLife
  • Molecular Biology of the Cell

John D. Aitchison has collaborated repeatedly with several coauthors, such as:

  • Fred D. Mast
  • Maxwell L. Neal (28 joint publications)
  • Fergal J. Duffy (18 joint publications)
  • Michael P. Rout (15 joint publications)
  • Alexis Kaushansky (15 joint publications)

The scientist's main fields of study cover medicine and biochemistry, genetics and molecular biology, with a strong emphasis on subfields like molecular biology, infectious diseases, public health, environmental and occupational health, immunology, and epidemiology.

Their principal research topics include:

  • SARS-CoV-2 and COVID-19 Research
  • Mosquito-borne diseases and control
  • Tuberculosis Research and Epidemiology
  • Malaria Research and Control
  • Vaccines and immunoinformatics approaches
  • Nuclear Structure and Function
  • RNA Research and Splicing

Best Publications

  • The Yeast Nuclear Pore Complex: Composition, Architecture, and Transport Mechanism

    Michael P. Rout;John D. Aitchison;Adisetyantari Suprapto;Kelly Hjertaas

  • Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

    John W. Schoggins;Donna A. MacDuff;Naoko Imanaka;Maria D. Gainey

  • Integrative structure and functional anatomy of a nuclear pore complex

    Seung Joong Kim;Javier Fernandez-Martinez;Ilona Nudelman;Yi Shi

  • Peroxisomes take shape

    Jennifer J. Smith;John D. Aitchison;John D. Aitchison

  • Virtual gating and nuclear transport: the hole picture.

    Michael P. Rout;John D. Aitchison;Marcelo O. Magnasco;Brian T. Chait

  • A Distinct Nuclear Import Pathway Used by Ribosomal Proteins

    Michael P Rout;Günter Blobel;John D Aitchison

  • Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins

    John D. Aitchison;Günter Blobel;Michael P. Rout

  • Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs

    Sean D. Taverna;Serge Ilin;Richard S. Rogers;Jason C. Tanny

  • A data integration methodology for systems biology.

    Daehee Hwang;Alistair G. Rust;Stephen Ramsey;Jennifer J. Smith

  • The nuclear pore complex as a transport machine.

    Michael P. Rout;John D. Aitchison

  • Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome

    Ulrike Kusebauch;David S. Campbell;Eric W. Deutsch;Caroline S. Chu

  • Comprehensive analysis of diverse ribonucleoprotein complexes

    Marlene Oeffinger;Karen E Wei;Richard Rogers;Jeffrey A DeGrasse

  • Karyopherins and kissing cousins.

    Richard W Wozniak;Michael P Rout;John D Aitchison

  • Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p.

    J D Aitchison;M P Rout;M Marelli;G Blobel

  • Transcriptome profiling to identify genes involved in peroxisome assembly and function

    Jennifer J. Smith;Marcello Marelli;Rowan H. Christmas;Franco J. Vizeacoumar

  • Approaching complete peroxisome characterization by gas-phase fractionation.

    Eugene C. Yi;Marcello Marelli;Hookeun Lee;Samuel O. Purvine

  • The Yeast Nuclear Pore Complex and Transport Through It

    John D. Aitchison;Michael P. Rout

  • Nup120p: a yeast nucleoporin required for NPC distribution and mRNA transport.

    J D Aitchison;G Blobel;M P Rout

  • Nup2p Dynamically Associates with the Distal Regions of the Yeast Nuclear Pore Complex

    David J. Dilworth;David J. Dilworth;Adisetyantari Suprapto;Julio C. Padovan;Brian T. Chait

  • Approaching complete peroxisome characterization by gas phase fractionation

    David R. Goodlett;Eugene C. Yi;Marcello Marelli;Samuel C. Purvine

Frequent Co-Authors

Michael P. Rout
Michael P. Rout Rockefeller University
Richard A. Rachubinski
Richard A. Rachubinski University of Alberta
Brian T. Chait
Brian T. Chait Rockefeller University
Nitin S. Baliga
Nitin S. Baliga University of Washington
Ilya Shmulevich
Ilya Shmulevich Institute for Systems Biology
Eugene C. Yi
Eugene C. Yi Seoul National University
David R. Goodlett
David R. Goodlett University of Victoria
Alan J. Tackett
Alan J. Tackett University of Arkansas for Medical Sciences
Leroy Hood
Leroy Hood University of Washington

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