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Biology and Biochemistry

D-Index
82
Citations
25594
World Ranking
3668
National Ranking
1826

Overview

Michael P. Rout is affiliated with Rockefeller University in the United States. Their research focuses predominantly on biochemistry, genetics, and molecular biology, with a significant number of publications in molecular biology and related subfields. They have also contributed to research in medicine, particularly infectious diseases, radiology, nuclear medicine and imaging, cardiology and cardiovascular medicine, as well as agronomy and crop science.

Their main topics of work include nuclear structure and function, RNA research and splicing, mechanisms of RNA and protein synthesis, SARS-CoV-2 and COVID-19 research, RNA modifications and cancer, monoclonal and polyclonal antibodies research, and genomics and chromatin dynamics.

Michael P. Rout has co-authored with several frequent collaborators, including:

  • Brian T. Chait
  • Andrej Šali
  • Javier Fernández-Martínez
  • Peter C. Fridy
  • Kelly R. Molloy

Their publications appear regularly in several journals and venues, with the highest number of works published in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Journal of Biological Chemistry
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • eLife

Recent notable papers by Michael P. Rout include:

  • "Comprehensive structure and functional adaptations of the yeast nuclear pore complex," 2022, Cell
  • "One Ring to Rule them All? Structural and Functional Diversity in the Nuclear Pore Complex," 2021, Trends in Biochemical Sciences
  • "Structures, functions and adaptations of the human LINE-1 ORF2 protein," 2023, Nature
  • "Replication and single-cycle delivery of SARS-CoV-2 replicons," 2021, Science
  • "Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape," 2021, eLife

Best Publications

  • The Yeast Nuclear Pore Complex: Composition, Architecture, and Transport Mechanism

    Michael P. Rout;John D. Aitchison;Adisetyantari Suprapto;Kelly Hjertaas

  • The molecular architecture of the nuclear pore complex

    Frank Alber;Svetlana Dokudovskaya;Liesbeth M. Veenhoff;Wenzhu Zhang

  • The Nuclear Pore Complex and Nuclear Transport

    Susan R. Wente;Michael P. Rout

  • Determining the architectures of macromolecular assemblies

    Frank Alber;Svetlana Dokudovskaya;Liesbeth M. Veenhoff;Wenzhu Zhang

  • The nuclear pore complex: bridging nuclear transport and gene regulation

    Caterina Strambio-De-Castillia;Mario Niepel;Michael P. Rout

  • Integrative structure and functional anatomy of a nuclear pore complex

    Seung Joong Kim;Javier Fernandez-Martinez;Ilona Nudelman;Yi Shi

  • A robust pipeline for rapid production of versatile nanobody repertoires

    Peter C Fridy;Yinyin Li;Sarah Keegan;Mary K Thompson

  • Three-Dimensional Architecture of the Isolated Yeast Nuclear Pore Complex: Functional and Evolutionary Implications

    Qing Yang;Michael P Rout;Christopher W Akey

  • Virtual gating and nuclear transport: the hole picture.

    Michael P. Rout;John D. Aitchison;Marcelo O. Magnasco;Brian T. Chait

  • Components of coated vesicles and nuclear pore complexes share a common molecular architecture.

    Damien P. Devos;Svetlana Dokudovskaya;Frank Alber;Rosemary Williams

  • A Distinct Nuclear Import Pathway Used by Ribosomal Proteins

    Michael P Rout;Günter Blobel;John D Aitchison

  • Simple rules for passive diffusion through the nuclear pore complex.

    Benjamin L. Timney;Barak Raveh;Roxana Mironska;Jill M. Trivedi

  • Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins

    John D. Aitchison;Günter Blobel;Michael P. Rout

  • Artificial nanopores that mimic the transport selectivity of the nuclear pore complex

    Tijana Jovanovic-Talisman;Jaclyn Tetenbaum-Novatt;Anna Sophia McKenney;Anton Zilman

  • Composition and Functional Characterization of Yeast 66S Ribosome Assembly Intermediates

    Piyanun Harnpicharnchai;Jelena Jakovljevic;Edward Horsey;Tiffany Miles

  • Induction of autophagy in axonal dystrophy and degeneration.

    Qing Jun Wang;Yaomei Ding;D Stave Kohtz;Noboru Mizushima

  • Isolation of the yeast nuclear pore complex.

    Michael P. Rout;Gfinter Blobel

  • Pores for thought: nuclear pore complex proteins

    Michael P. Rout;Susan R. Wente

  • Components of the yeast spindle and spindle pole body.

    M P Rout;J V Kilmartin

  • The nuclear pore complex as a transport machine.

    Michael P. Rout;John D. Aitchison

Frequent Co-Authors

Brian T. Chait
Brian T. Chait Rockefeller University
Andrej Sali
Andrej Sali University of California, San Francisco
John D. Aitchison
John D. Aitchison University of Minnesota
Mark C. Field
Mark C. Field University of Dundee
David Cowburn
David Cowburn Albert Einstein College of Medicine
Damien P. Devos
Damien P. Devos Pasteur Institute of Lille
Ileana M. Cristea
Ileana M. Cristea Princeton University
David Fenyö
David Fenyö New York University
Stephen K. Burley
Stephen K. Burley Rutgers, The State University of New Jersey
Martin S. Taylor
Martin S. Taylor Harvard University

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