World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
112
Citations
62836
World Ranking
879
National Ranking
549

Research.com Recognitions

  • 1995 - Fellow of the Royal Society of Canada Academy of Science

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Stephen K. Burley focuses on Stereochemistry, Protein structure, Genetics, Biochemistry and Molecular biology. He combines subjects such as Antiparallel, Crystallography, DNA, DNA-binding protein and van der Waals force with his study of Stereochemistry. He interconnects Type VI secretion system, Biophysics, Computational biology and Gene in the investigation of issues within Protein structure.

His study in Genetics is interdisciplinary in nature, drawing from both Structural genomics and Data science. Many of his studies involve connections with topics such as Antidote and Biochemistry. His Molecular biology study integrates concerns from other disciplines, such as RNA, TATA box, Cell biology, EIF4E and Transcription.

His most cited work include:

  • Weight-reducing effects of the plasma protein encoded by the obese gene. (4141 citations)
  • Aromatic-aromatic interaction: a mechanism of protein structure stabilization (1902 citations)
  • Co-crystal structure of the HNF-3/ fork head DNA-recognition motif resembles histone H5 (1062 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Stereochemistry, Protein structure, Protein Data Bank and Crystallography. His studies deal with areas such as Antiparallel, Crystal structure and Amidohydrolase, Enzyme, Active site as well as Stereochemistry. A large part of his Protein structure studies is devoted to Structural genomics.

The Protein Data Bank study combines topics in areas such as World Wide Web, Computational biology, Protein Data Bank and Data science. As a member of one scientific family, Stephen K. Burley mostly works in the field of Computational biology, focusing on Genetics and, on occasion, Cell biology. His research in Protein Data Bank intersects with topics in Bioinformatics and Structural bioinformatics.

He most often published in these fields:

  • Biochemistry (35.95%)
  • Stereochemistry (28.68%)
  • Protein structure (22.00%)

What were the highlights of his more recent work (between 2017-2021)?

  • Protein Data Bank (20.24%)
  • Protein Data Bank (20.04%)
  • Computational biology (14.54%)

In recent papers he was focusing on the following fields of study:

His main research concerns Protein Data Bank, Protein Data Bank, Computational biology, World Wide Web and Severe acute respiratory syndrome coronavirus 2. The concepts of his Protein Data Bank study are interwoven with issues in Metadata, External Data Representation, Structural biology, Biomedicine and Data science. His research integrates issues of Macromolecular crystallography and Structural bioinformatics in his study of Protein Data Bank.

In Macromolecular crystallography, Stephen K. Burley works on issues like Crystallography, which are connected to Data dictionary. Stephen K. Burley has included themes like Protein structure, Drug discovery and Molecular targets in his Computational biology study. In his work, he performs multidisciplinary research in Protein structure and Human metabolism.

Between 2017 and 2021, his most popular works were:

  • RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy. (409 citations)
  • Recon3D enables a three-dimensional view of gene variation in human metabolism. (229 citations)
  • Recon3D enables a three-dimensional view of gene variation in human metabolism. (229 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Stephen K. Burley mainly investigates Protein Data Bank, Protein Data Bank, Computational biology, Data science and Pose prediction. His research ties Structural biology and Protein Data Bank together. His Protein Data Bank study combines topics in areas such as Metadata, Macromolecular crystallography and Structural bioinformatics.

While the research belongs to areas of Metadata, Stephen K. Burley spends his time largely on the problem of Bioinformatics, intersecting his research to questions surrounding World Wide Web. His studies in Macromolecular crystallography integrate themes in fields like Crystallography and Data dictionary. He has researched Computational biology in several fields, including Metabolite, Variation, Human genome and Gene.

Best Publications

  • Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

    Jeffrey L. Halaas;Ketan S. Gajiwala;Margherita Maffei;Steven L. Cohen

  • Aromatic-aromatic interaction: a mechanism of protein structure stabilization

    S. K. Burley;S. K. Burley;G. A. Petsko

  • Co-crystal structure of the HNF-3/ fork head DNA-recognition motif resembles histone H5

    Kirk L. Clark;Elaine D Halay;Elaine D Halay;Eseng Lai;Stephen K Burley;Stephen K Burley

  • RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences.

    Stephen K. Burley;Charmi Bhikadiya;Chunxiao Bi;Sebastian Bittrich

  • Co-crystal structure of TBP recognizing the minor groove of a TATA element

    Joseph L. Kim;Dimitar B. Nikolov;Stephen K. Burley

  • Protein Data Bank: the single global archive for 3D macromolecular structure data

    Stephen K Burley;Helen M Berman;Charmi Bhikadiya

  • RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy.

    Stephen K. Burley;Helen M. Berman;Charmi Bhikadiya;Chunxiao Bi

  • Protein Data Bank (PDB): The Single Global Macromolecular Structure Archive.

    Stephen K. Burley;Stephen K. Burley;Helen M. Berman;Gerard J. Kleywegt;John L. Markley

  • Hierarchical phosphorylation of the translation inhibitor 4E-BP1

    Anne-Claude Gingras;Brian Raught;Steven P. Gygi;Steven P. Gygi;Anna Niedzwiecka

  • Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures.

    David Sehnal;David Sehnal;David Sehnal;Sebastian Bittrich;Mandar S Deshpande;Radka Svobodová;Radka Svobodová

  • Weakly Polar Interactions In Proteins

    S K Burley;G A Petsko

  • BIOCHEMISTRY AND STRUCTURAL BIOLOGY OF TRANSCRIPTION FACTOR IID (TFIID)

    S. K. Burley;R. G. Roeder

  • Protein production and purification.

    S Gräslund

  • The RCSB protein data bank: integrative view of protein, gene and 3D structural information

    Peter W. Rose;Andreas Prlić;Ali Altunkaya;Chunxiao Bi

  • Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain.

    Adrian R. Ferré-D'Amaré;George C. Prendergast;George C. Prendergast;Edward B. Ziff;Stephen K. Burley;Stephen K. Burley

  • Amino-aromatic interactions in proteins

    Stephen Burley;Stephen Burley;G. A. Petsko

  • Cocrystal Structure of the Messenger RNA 5′ Cap-Binding Protein (eIF4E) Bound to 7-methyl-GDP

    Joseph Marcotrigiano;Anne-Claude Gingras;Nahum Sonenberg;Stephen K. Burley;Stephen K. Burley;Stephen K. Burley

  • Crystal structure of a TFIIB-TBP-TATA-element ternary complex.

    Dimitar B. Nikolov;Hua Chen;Hua Chen;Elaine D. Halay;Elaine D. Halay;Anny A. Usheva

  • Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin

    Petr G. Leiman;Petr G. Leiman;Marek Basler;Udupi A. Ramagopal;Jeffrey B. Bonanno

  • Winged helix proteins.

    Ketan S Gajiwala;Stephen K Burley;Stephen K Burley

Frequent Co-Authors

John D. Westbrook
John D. Westbrook Rutgers, The State University of New Jersey
Helen M. Berman
Helen M. Berman Rutgers, The State University of New Jersey
Andrej Sali
Andrej Sali University of California, San Francisco
Sameer Velankar
Sameer Velankar European Bioinformatics Institute
David S. Goodsell
David S. Goodsell Rutgers, The State University of New Jersey
John L. Markley
John L. Markley University of Wisconsin–Madison
Steven C. Almo
Steven C. Almo Albert Einstein College of Medicine
Haruki Nakamura
Haruki Nakamura Osaka University
Frank M. Raushel
Frank M. Raushel Texas A&M University
Andreas Prlić
Andreas Prlić Invitae (United States)

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